Development Level

Tbio 116 | 10,625
Tchem 6 | 1,890
Tdark 4 | 7,003

IMPC Term

preweaning lethality, complete... 5 | 633
embryonic lethality prior to t... 3 | 187
abnormal body wall morphology 2 | 7
abnormal craniofacial morpholo... 2 | 12
abnormal facial morphology 2 | 9
abnormal lens morphology 2 | 73
abnormal limb bud morphology 2 | 15
abnormal limb morphology 2 | 7
anophthalmia 2 | 20
cleft palate 2 | 6
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased mean corpuscular vol... 2 | 50
decreased total body fat amoun... 2 | 186
edema 2 | 11
embryonic lethality prior to o... 2 | 148
facial cleft 2 | 3
polydactyly 2 | 22
abnormal QRS complex 1 | 25
abnormal digit morphology 1 | 13
abnormal kidney morphology 1 | 30
abnormal posture 1 | 5
abnormal retinal blood vessel ... 1 | 18
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased circulating amylase ... 1 | 24
decreased circulating aspartat... 1 | 27
decreased circulating insulin ... 1 | 75
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 19
enlarged heart 1 | 111
hydrometra 1 | 13
impaired righting response 1 | 19
increased bone mineral content 1 | 92
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased neutrophil cell numb... 1 | 15
increased spleen weight 1 | 3
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

Cancer 84 | 2,346
psoriasis 74 | 6,685
Ankylosing spondylitis 71 | 138
diabetes mellitus 64 | 1,663
Hypersensitivity reaction type II disease 59 | 235
Arthritis 58 | 248
Acquired immunodeficiency syndrome 57 | 164
Juvenile rheumatoid arthritis 57 | 104
Uveitis 57 | 103
Behcet's disease 56 | 74
Psoriatic arthritis 49 | 83
Rheumatoid Arthritis 42 | 1,160
Stevens-Johnson syndrome 37 | 78
ovarian cancer 37 | 8,484
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Takayasu's arteritis 35 | 52
glioblastoma 32 | 5,572
osteosarcoma 30 | 7,933
Kidney disease 27 | 396
lung carcinoma 26 | 2,844
Leprosy 25 | 77
Multiple Sclerosis 25 | 498
lung cancer 25 | 4,466
medulloblastoma, large-cell 25 | 6,234
Anemia 24 | 252
Hemochromatosis 23 | 55
Liver disease 23 | 219
pilocytic astrocytoma 22 | 3,086
Hepatitis B 21 | 103
Primary immunodeficiency disease 21 | 52
Skin disease 21 | 65
ulcerative colitis 16 | 2,087
Human immunodeficiency virus infectious disease 15 | 92
pre-eclampsia 15 | 67
subependymal giant cell astrocytoma 15 | 2,287
atypical teratoid / rhabdoid tumor 14 | 4,369
invasive ductal carcinoma 14 | 2,950
pediatric high grade glioma 14 | 2,712
Multiple myeloma 13 | 1,327
cutaneous lupus erythematosus 12 | 1,056
malignant mesothelioma 12 | 3,162
non-small cell lung cancer 12 | 2,798
pancreatic cancer 12 | 2,300
astrocytoma 11 | 1,493
interstitial cystitis 10 | 2,299
posterior fossa group A ependymoma 10 | 1,511
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
juvenile dermatomyositis 9 | 1,189
Breast cancer 8 | 3,094
ependymoma 8 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
lung adenocarcinoma 8 | 2,713
primary Sjogren syndrome 8 | 789
primitive neuroectodermal tumor 8 | 3,031
tuberculosis 8 | 1,557
medulloblastoma 7 | 1,524
oligodendroglioma 7 | 2,849
primary pancreatic ductal adenocarcinoma 7 | 1,271
active Crohn's disease 6 | 918
breast carcinoma 6 | 1,614
dermatomyositis 6 | 933
gastric carcinoma 6 | 832
group 4 medulloblastoma 6 | 1,875
pituitary cancer 6 | 1,972
Duchenne muscular dystrophy 5 | 602
HIV Infections 5 | 100
IGA Glomerulonephritis 5 | 454
Neurodegenerative disease 5 | 383
Pick disease 5 | 1,893
adrenocortical carcinoma 5 | 1,427
adult high grade glioma 5 | 2,148
astrocytic glioma 5 | 2,241
cystic fibrosis 5 | 1,665
mucosa-associated lymphoid tissue lymphoma 5 | 480
Glioma 4 | 65
Hermansky-Pudlak syndrome 4 | 43
Osteopetrosis 4 | 40
aldosterone-producing adenoma 4 | 664
colon cancer 4 | 1,475
esophageal adenocarcinoma 4 | 737
group 3 medulloblastoma 4 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
periodontitis 4 | 269
posterior fossa group B ependymoma 4 | 1,530
Asthma 3 | 349
Atherosclerosis 3 | 275
Carcinoma 3 | 2,147
Hypertension 3 | 287
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) 3 | 12
Prostatic Neoplasms 3 | 471
active ulcerative colitis 3 | 477
acute myeloid leukemia 3 | 780
atypical teratoid/rhabdoid tumor 3 | 1,095
hepatocellular carcinoma 3 | 532
nasopharyngeal carcinoma 3 | 1,056
sonic hedgehog group medulloblastoma 3 | 1,482
spina bifida 3 | 1,064
tuberculosis and treatment for 6 months 3 | 686

Tissue

Blood and immune system 64 | 17,995
Cardiovascular System 64 | 17,958
Digestive Tract 64 | 18,473
Endocrine System 64 | 18,512
Female tissues 64 | 18,647
Liver and Pancreas 64 | 18,136
Male tissues 64 | 17,969
Nervous System 64 | 18,561
Respiratory system 64 | 17,484
Urinary Tract 64 | 18,444
Skin and soft tissues 57 | 18,115

Target Family

Non-IDG 90 | 11,971
Enzyme 32 | 4,146
Kinase 2 | 634
Ion Channel 1 | 341
Transporter 1 | 473

Compartment GO Term

Phagocytic vesicle membrane 126 | 126
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

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