Development Level

Tbio 49 | 11,445
Tchem 10 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

decreased circulating choleste... 3 | 93
decreased vertical activity 3 | 208
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
abnormal tail morphology 2 | 25
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal radius morphology 1 | 8
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating fructosa... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased heart rate variabili... 1 | 13
decreased large unstained cell... 1 | 11
enlarged spleen 1 | 41
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
long tail 1 | 1
male infertility 1 | 123
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
shortened RR interval 1 | 17
thick tail 1 | 1

Disease

Carcinoma 43 | 11,493
ovarian cancer 35 | 8,520
psoriasis 31 | 6,694
Zellweger syndrome 27 | 37
osteosarcoma 25 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
Autosomal recessive predisposition 24 | 1,442
Infantile Refsum disease 20 | 23
medulloblastoma, large-cell 20 | 6,241
Epilepsy 19 | 792
Seizures 19 | 596
glioblastoma 19 | 5,792
Cataract 18 | 297
Chondrodysplasia punctata 18 | 41
Failure to gain weight 18 | 365
Pediatric failure to thrive 18 | 365
Muscle hypotonia 17 | 571
Peroxisomal disease 17 | 22
Sensorineural Hearing Loss (disorder) 17 | 284
Short stature 17 | 531
ependymoma 17 | 4,679
lung cancer 17 | 4,740
Concave bridge of nose 16 | 195
Depressed nasal bridge 16 | 195
Depressed nasal root/bridge 16 | 195
Hepatomegaly 16 | 285
Low Vision 16 | 174
Nystagmus 16 | 317
Retinitis Pigmentosa 16 | 226
Visual Impairment 16 | 174
Abnormality of metabolism/homeostasis 15 | 134
Adrenoleukodystrophy 15 | 29
Cerebellar Ataxia 15 | 304
Cognitive delay 15 | 608
Developmental regression 15 | 95
Global developmental delay 15 | 608
Hypoplastic mandible condyle 15 | 275
Lens Opacities 15 | 231
Loss of developmental milestones 15 | 95
Mandibular hypoplasia 15 | 275
Mental and motor retardation 15 | 608
Mental deterioration in childhood 15 | 95
Micrognathism 15 | 275
Muscle Spasticity 15 | 195
Neurodevelopmental regression 15 | 95
Psychomotor regression 15 | 95
Psychomotor regression beginning in infancy 15 | 95
Psychomotor regression in infants 15 | 95
Psychomotor regression, progressive 15 | 95
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
malignant mesothelioma 15 | 3,232
Abnormal skeletal development 14 | 60
Abnormality of retinal pigmentation 14 | 111
Addison Disease 14 | 18
Adrenal cortical hypofunction 14 | 23
Blepharoptosis 14 | 231
Broad flat nasal bridge 14 | 236
Byzanthine arch palate 14 | 194
Congenital Epicanthus 14 | 177
Difficulties with night vision 14 | 87
Elevated levels of phytanic acid 14 | 15
High forehead 14 | 102
Liver Failure 14 | 73
Nasal bridge wide 14 | 236
Night Blindness 14 | 101
Optic Atrophy 14 | 242
Osteochondrodysplasias 14 | 72
Respiratory Insufficiency 14 | 132
Respiratory function loss 14 | 121
Retinal pigment epithelial abnormality 14 | 111
Small head 14 | 374
Stippled epiphyses 14 | 28
Strabismus 14 | 270
Tall forehead 14 | 102
Upward slant of palpebral fissure 14 | 75
atypical teratoid / rhabdoid tumor 14 | 5,112
Anteverted nostril 13 | 191
Big calvaria 13 | 147
Death in early childhood 13 | 82
Death in infancy 13 | 82
Electroencephalogram abnormal 13 | 101
Feeding difficulties in infancy 13 | 175
Flat face 13 | 52
Global developmental delay, severe 13 | 47
Hyperreflexia 13 | 209
Icterus 13 | 82
Increased head circumference 13 | 147
Increased size of cranium 13 | 147
Increased size of skull 13 | 147
Liver diseases 13 | 87
Long narrow head 13 | 75
Narrow cranium shape 13 | 75
Narrow head shape 13 | 75
Narrow skull shape 13 | 75
Neonatal adrenoleukodystrophy 13 | 14
Polymicrogyria 13 | 48
Premature Birth 13 | 77
Severe psychomotor retardation 13 | 47
Turridolichocephaly 13 | 75
interstitial cystitis 13 | 2,312

Tissue

Liver and Pancreas 63 | 16,750
Urinary Tract 63 | 16,678
Blood and immune system 62 | 16,909
Digestive Tract 62 | 17,369
Endocrine System 62 | 18,159
Skin and soft tissues 62 | 17,230
Female tissues 61 | 17,400
Nervous System 61 | 16,725
Male tissues 60 | 17,142
Respiratory system 60 | 16,393
Cardiovascular System 56 | 15,192

Target Family

Enzyme 38 | 4,145
Non-IDG 22 | 12,091
Transporter 3 | 473

Compartment GO Term

Peroxisomal matrix 63 | 63
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Lon protease homolog 2, peroxisomal LONP2 Tbio Enzyme -1.00177 8.20 100
ATP-binding cassette sub-family D member 3 ABCD3 Tbio Transporter -1.82051 64.2 166
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
Malonyl-CoA decarboxylase, mitochondrial MLYCD Tchem Enzyme -1.70434 46.1 67
Acyl-coenzyme A thioesterase 4 ACOT4 Tbio Enzyme -0.53787 2.87 58
Ketimine reductase mu-crystallin CRYM Tbio Enzyme -1.70644 52.5 199
Peroxisomal targeting signal 1 receptor PEX5 Tbio Non-IDG -2.43126 272.8 138
Peroxisome biogenesis factor 1 PEX1 Tbio Enzyme -0.77059 5.43 107
Fatty acyl-CoA reductase 1 FAR1 Tbio Enzyme -1.65427 43.8 27