Development Level

Tbio 22 | 11,445
Tdark 7 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal tail morphology 2 | 25
decreased body weight 2 | 161
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal facial morphology 1 | 17
abnormal femur morphology 1 | 14
abnormal head shape 1 | 10
abnormal joint morphology 1 | 23
abnormal limb morphology 1 | 13
abnormal outer ear morphology 1 | 3
abnormal radius morphology 1 | 8
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
long tail 1 | 1
male infertility 1 | 123
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499
thick tail 1 | 1
thrombocytosis 1 | 27

Disease

Zellweger syndrome 16 | 37
psoriasis 15 | 6,694
Epilepsy 14 | 792
Infantile Refsum disease 14 | 23
Abnormality of metabolism/homeostasis 13 | 134
Cataract 13 | 297
Concave bridge of nose 13 | 195
Depressed nasal bridge 13 | 195
Depressed nasal root/bridge 13 | 195
Developmental regression 13 | 95
Loss of developmental milestones 13 | 95
Mental deterioration in childhood 13 | 95
Muscle hypotonia 13 | 571
Neurodevelopmental regression 13 | 95
Nystagmus 13 | 317
Psychomotor regression 13 | 95
Psychomotor regression beginning in infancy 13 | 95
Psychomotor regression in infants 13 | 95
Psychomotor regression, progressive 13 | 95
Respiratory Insufficiency 13 | 132
Respiratory function loss 13 | 121
Retinitis Pigmentosa 13 | 226
Seizures 13 | 596
Sensorineural Hearing Loss (disorder) 13 | 284
Abnormal skeletal development 12 | 60
Abnormality of retinal pigmentation 12 | 111
Blepharoptosis 12 | 231
Broad flat nasal bridge 12 | 236
Carcinoma 12 | 11,493
Cerebellar Ataxia 12 | 304
Cognitive delay 12 | 608
Congenital Epicanthus 12 | 177
Death in early childhood 12 | 82
Death in infancy 12 | 82
Difficulties with night vision 12 | 87
Electroencephalogram abnormal 12 | 101
Elevated levels of phytanic acid 12 | 15
Failure to gain weight 12 | 365
Flat face 12 | 52
Global developmental delay 12 | 608
Global developmental delay, severe 12 | 47
Hepatomegaly 12 | 285
Hyperreflexia 12 | 209
Hypoplastic mandible condyle 12 | 275
Lens Opacities 12 | 231
Low Vision 12 | 174
Mandibular hypoplasia 12 | 275
Mental and motor retardation 12 | 608
Micrognathism 12 | 275
Muscle Spasticity 12 | 195
Nasal bridge wide 12 | 236
Night Blindness 12 | 101
Optic Atrophy 12 | 242
Osteochondrodysplasias 12 | 72
Pediatric failure to thrive 12 | 365
Peroxisomal disease 12 | 22
Retinal pigment epithelial abnormality 12 | 111
Severe psychomotor retardation 12 | 47
Short stature 12 | 531
Small head 12 | 374
Stippled epiphyses 12 | 28
Strabismus 12 | 270
Upward slant of palpebral fissure 12 | 75
Visual Impairment 12 | 174
ovarian cancer 12 | 8,520
Abnormal behavior 11 | 52
Addison Disease 11 | 18
Adrenal cortical hypofunction 11 | 23
Adrenoleukodystrophy, Neonatal 11 | 13
Anteverted nostril 11 | 191
Bilateral single transverse palmar creases 11 | 34
Byzanthine arch palate 11 | 194
Clouding of corneal stroma 11 | 50
Corneal Opacity 11 | 53
Decreased to absent deep tendon reflexes 11 | 42
Embryotoxon 11 | 28
Flat occiput 11 | 26
High forehead 11 | 102
Hydronephrosis 11 | 89
Hypertrophy of clitoris 11 | 40
Hypotonia, severe 11 | 33
Icterus 11 | 82
Impaired cognition 11 | 96
Infantile Refsum Disease (disorder) 11 | 13
Liver Failure 11 | 73
Liver diseases 11 | 87
Long narrow head 11 | 75
Malformations of Cortical Development, Group II 11 | 31
Malformed pinnae 11 | 37
Mental impairment 11 | 95
Movement Disorders 11 | 55
Muscle weakness, progressive 11 | 22
Penile hypospadias 11 | 106
Polymicrogyria 11 | 48
Posterior embryotoxon 11 | 28
Premature Birth 11 | 77
Premature birth of newborn 11 | 67
Psychomotor retardation, profound 11 | 17
Pyloric Stenosis 11 | 47
Visual field constriction 11 | 36

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Female tissues 28 | 17,400
Male tissues 28 | 17,142
Skin and soft tissues 28 | 17,230
Endocrine System 27 | 18,159
Liver and Pancreas 27 | 16,750
Respiratory system 27 | 16,393
Urinary Tract 27 | 16,678
Nervous System 26 | 16,725
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 4 | 4,145
GPCR 2 | 408
Transporter 2 | 473

Compartment GO Term

Peroxisomal importomer complex 29 | 29
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA fragmentation factor subunit alpha DFFA Tbio Non-IDG -2.50636 314.8 667
Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 Tbio Enzyme -2.10178 116.1 292
Peroxisomal biogenesis factor 19 PEX19 Tbio Non-IDG -2.28877 200.1 264
Peroxisomal membrane protein PEX14 PEX14 Tbio Non-IDG -1.56143 37.1 205
Protein LZIC LZIC Tdark Non-IDG -0.32003 2.44 204
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Leucine-rich repeat-containing G-protein coupled receptor 6 LGR6 Tbio GPCR -1.41906 26.5 156
Peroxisome assembly factor 2 PEX6 Tbio Enzyme -1.89379 79.8 148
Peroxisomal targeting signal 1 receptor PEX5 Tbio Non-IDG -2.43126 272.8 138
Peroxisomal membrane protein 11A PEX11A Tbio Non-IDG -1.72726 55.8 122