Development Level

Tbio 24 | 11,445
Tdark 11 | 6,588
Tchem 5 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

decreased bone mineral content 3 | 151
abnormal behavior 2 | 298
abnormal cranium morphology 2 | 36
abnormal head morphology 2 | 10
decreased body length 2 | 101
decreased body weight 2 | 161
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal lung morphology 1 | 26
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 38 | 11,493
osteosarcoma 24 | 7,950
ovarian cancer 24 | 8,520
group 3 medulloblastoma 17 | 4,104
ependymoma 16 | 4,679
glioblastoma 16 | 5,792
medulloblastoma, large-cell 16 | 6,241
Kidney cancer 14 | 2,613
atypical teratoid / rhabdoid tumor 12 | 5,112
Autosomal recessive predisposition 11 | 1,442
Breast cancer 11 | 3,578
Intellectual disability 11 | 1,016
Microcephaly 11 | 166
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
psoriasis 11 | 6,694
malignant mesothelioma 10 | 3,232
Short stature 8 | 531
nasopharyngeal carcinoma 8 | 1,058
primitive neuroectodermal tumor 8 | 3,035
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 7 | 16
Seckel syndrome 7 | 34
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Astrocytoma, Pilocytic 6 | 3,081
Cancer 6 | 2,499
Cognitive delay 6 | 608
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Microcephalic osteodysplastic primordial dwarfism type II 6 | 13
Pick disease 6 | 1,894
Poor school performance 6 | 645
Small head 6 | 374
astrocytic glioma 6 | 2,597
chronic rhinosinusitis 6 | 512
lung cancer 6 | 4,740
Rheumatoid arthritis 5 | 1,191
Sloping forehead 5 | 46
adrenocortical carcinoma 5 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
non primary Sjogren syndrome sicca 5 | 891
oligodendroglioma 5 | 2,850
progressive supranuclear palsy 5 | 676
tuberculosis 5 | 2,010
Ciliopathy 4 | 71
Cone-shaped epiphyses 4 | 24
Craniosynostosis 4 | 74
Delayed bone age 4 | 136
Fetal Growth Retardation 4 | 189
Hip Dislocation, Congenital 4 | 48
Hypoplastic mandible condyle 4 | 275
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Polydactyly 4 | 107
Severe mental retardation (I.Q. 20-34) 4 | 99
Ulnar polydactyly of fingers 4 | 47
Upward slant of palpebral fissure 4 | 75
colon cancer 4 | 1,478
group 4 medulloblastoma 4 | 1,855
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
Abnormal cortical bone morphology 3 | 22
Bilateral fifth finger clinodactyly 3 | 110
Brachydactyly 3 | 156
Cachexia 3 | 50
Curvature of little finger 3 | 110
Dilated ventricles (finding) 3 | 121
Downward slant of palpebral fissure 3 | 158
Ectopic Tissue 3 | 14
Frontal lobe hypoplasia 3 | 9
Glaucoma 3 | 239
Hyperreflexia 3 | 209
Impaired cognition 3 | 96
Joint hyperflexibility 3 | 78
Mental impairment 3 | 95
Pachygyria 3 | 41
Retrognathia 3 | 54
Schizophrenia 3 | 1,160
Skull malformation 3 | 38
Thin upper lip vermilion 3 | 67
Unilateral agenesis of kidney 3 | 20
Vesico-Ureteral Reflux 3 | 33
active ulcerative colitis 3 | 764
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
posterior fossa group A ependymoma 3 | 468
posterior fossa group B ependymoma 3 | 416
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819

Tissue

Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Cardiovascular System 40 | 15,192
Urinary Tract 40 | 16,678

Target Family

Non-IDG 34 | 12,091
Kinase 4 | 634
Enzyme 3 | 4,145

Compartment GO Term

Pericentriolar material 41 | 41
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Centlein CNTLN Tbio Non-IDG -2.28518 122.3 76
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23
Coiled-coil domain-containing protein 38 CCDC38 Tdark Non-IDG -0.33995 2.17 125
Centromere protein J CENPJ Tbio Non-IDG -1.79588 59.0 102
Centrosomal protein of 128 kDa CEP128 Tdark Non-IDG 0.18 0.11 79
Centrosomal protein of 152 kDa CEP152 Tbio Non-IDG -1.23896 18.1 117
CDK5 regulatory subunit-associated protein 2 CDK5RAP2 Tbio Non-IDG -1.70804 54.4 81
Coiled-coil domain-containing protein 81 CCDC81 Tdark Non-IDG -0.05115 1.11 85
Serine/threonine-protein kinase Nek1 NEK1 Tchem Kinase -1.62443 47.0 85