Development Level

Tbio 38 | 11,445
Tchem 14 | 1,598
Tdark 3 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
cataract 3 | 92
increased lean body mass 3 | 172
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased hemoglobin content 2 | 68
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased body length 2 | 32
increased bone mineral content 2 | 108
increased circulating creatini... 2 | 38
small spleen 2 | 19
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal heart looping 1 | 5
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small testis 1 | 58
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 38 | 8,520
Carcinoma 36 | 11,493
psoriasis 28 | 6,694
glioblastoma 27 | 5,792
group 3 medulloblastoma 27 | 4,104
osteosarcoma 27 | 7,950
medulloblastoma, large-cell 26 | 6,241
Cancer 25 | 2,499
atypical teratoid / rhabdoid tumor 25 | 5,112
lung cancer 22 | 4,740
Breast cancer 19 | 3,578
primitive neuroectodermal tumor 19 | 3,035
adult high grade glioma 16 | 3,801
invasive ductal carcinoma 16 | 2,951
ependymoma 15 | 4,679
oligodendroglioma 14 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
malignant mesothelioma 13 | 3,232
non-small cell lung cancer 13 | 2,890
Kidney cancer 11 | 2,613
lung adenocarcinoma 11 | 2,716
astrocytic glioma 10 | 2,597
subependymal giant cell astrocytoma 10 | 2,287
Astrocytoma, Pilocytic 9 | 3,081
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
breast carcinoma 8 | 1,638
pancreatic cancer 8 | 2,398
Melanoma 7 | 711
Pick disease 7 | 1,894
adrenocortical carcinoma 7 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Intellectual disability 6 | 1,016
Multiple myeloma 6 | 1,332
acute quadriplegic myopathy 6 | 1,158
juvenile dermatomyositis 6 | 1,187
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
tuberculosis 6 | 2,010
Bladder Neoplasm 5 | 112
Breast Neoplasms 5 | 445
MYELODYSPLASTIC SYNDROME 5 | 53
Mammary Neoplasms 5 | 425
Muscle hypotonia 5 | 571
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
Short stature 5 | 531
Small head 5 | 374
Urinary Bladder Neoplasms 5 | 114
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
pituitary cancer 5 | 1,972
tuberculosis and treatment for 6 months 5 | 409
ulcerative colitis 5 | 1,819
Alzheimer's disease 4 | 658
Cleft Palate 4 | 271
Cognitive delay 4 | 608
Cryptorchidism 4 | 296
Dull intelligence 4 | 645
Epilepsy 4 | 792
Glaucoma 4 | 239
Glioma 4 | 74
Global developmental delay 4 | 608
Immune system cancer 4 | 140
Low intelligence 4 | 645
Lymphoid leukemia 4 | 160
Melanocytic nevus 4 | 43
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Myelodysplastic Syndromes 4 | 26
Poor school performance 4 | 645
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Sensorineural Hearing Loss (disorder) 4 | 284
Stomach Neoplasms 4 | 300
Strabismus 4 | 270
Waldenstrons macroglobulinemia 4 | 765
cystic fibrosis 4 | 1,696
hearing impairment 4 | 199
interstitial cystitis 4 | 2,312
spina bifida 4 | 1,074
Adenoid Cystic Carcinoma 3 | 99
Adenoma 3 | 167
Atopic dermatitis 3 | 952
Carcinoma, Adenoid Cystic 3 | 99
Colonic Neoplasms 3 | 142
Disease Progression 3 | 136
Endometriosis 3 | 540
Liver cancer 3 | 604
Long philtrum 3 | 137
Lung Neoplasms 3 | 232
Neoplasm Invasiveness 3 | 161
Ventricular Septal Defects 3 | 119
diabetes mellitus 3 | 1,728
medulloblastoma 3 | 720
progressive supranuclear palsy 3 | 676

Tissue

Blood and immune system 55 | 16,909
Digestive Tract 55 | 17,369
Endocrine System 55 | 18,159
Female tissues 55 | 17,400
Liver and Pancreas 55 | 16,750
Male tissues 55 | 17,142
Respiratory system 55 | 16,393
Skin and soft tissues 55 | 17,230
Urinary Tract 55 | 16,678
Nervous System 54 | 16,725
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 25 | 12,091
Epigenetic 19 | 242
Enzyme 6 | 4,145
Transcription Factor 5 | 1,400
TF/Epigenetic 2 | 38

Compartment GO Term

PcG protein complex 57 | 57
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PHD finger protein 1 PHF1 Tbio Epigenetic -2.14039 127.5 199
Polycomb group RING finger protein 1 PCGF1 Tbio Non-IDG -0.99091 11.4 101
Chromobox protein homolog 8 CBX8 Tchem Epigenetic -2.27537 183.4 505
Polycomb group RING finger protein 3 PCGF3 Tdark Non-IDG -0.48328 1.97 115
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125
Lysine-specific demethylase 6B KDM6B Tchem Epigenetic -2.22888 174.2 272
Chromobox protein homolog 2 CBX2 Tchem Epigenetic -1.37369 24.3 223
Lysine-specific demethylase 6A KDM6A Tchem Epigenetic -2.27999 176.8 119
Sex comb on midleg-like protein 2 SCML2 Tbio Epigenetic -1.20453 16.3 103
Lysine-specific demethylase 2B KDM2B Tchem Epigenetic -1.56328 41.7 248