Development Level

Tchem 6 | 1,598
Tclin 4 | 613
Tbio 3 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

increased mean corpuscular hem... 2 | 96
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
increased B cell number 1 | 9
increased circulating LDL chol... 1 | 13
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
preweaning lethality, incomple... 1 | 499

Disease

Cancer 12 | 2,499
glioblastoma 11 | 5,792
ovarian cancer 11 | 8,520
Carcinoma 10 | 11,493
atypical teratoid / rhabdoid tumor 10 | 5,112
Breast cancer 8 | 3,578
Lung Neoplasms 8 | 232
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
Adenocarcinoma 7 | 122
Adenoma 7 | 167
Breast Neoplasms 7 | 445
Kidney cancer 7 | 2,613
Mammary Neoplasms 7 | 425
Ovarian Neoplasms 7 | 102
Renal Cell Carcinoma 7 | 214
breast carcinoma 7 | 1,638
lung cancer 7 | 4,740
pancreatic cancer 7 | 2,398
psoriasis 7 | 6,694
Autosomal recessive predisposition 6 | 1,442
Carcinoma, Hepatocellular 6 | 228
Endometrial cancer 6 | 311
Epilepsy 6 | 792
Liver carcinoma 6 | 240
Neoplasm Metastasis 6 | 168
Papilloma 6 | 44
Prostatic Neoplasms 6 | 495
Schizophrenia 6 | 1,160
Squamous cell carcinoma 6 | 129
Stomach Neoplasms 6 | 300
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
ovarian neoplasm 6 | 99
Carcinoma, Renal Cell 5 | 124
Carcinoma, Squamous Cell 5 | 110
Cholangiocarcinoma 5 | 35
Colorectal Neoplasms 5 | 243
DOID:2627 5 | 94
Endometriosis 5 | 540
Familial adenomatous polyposis 5 | 32
Intellectual disability 5 | 1,016
Parkinson's disease 5 | 392
Seizures 5 | 596
Somatic mutation 5 | 61
Transitional cell carcinoma of bladder 5 | 17
Upper respiratory tract disease 5 | 15
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
nasopharyngeal carcinoma 5 | 1,058
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Abnormality of metabolism/homeostasis 4 | 134
Acquired scoliosis 4 | 281
Anemia 4 | 365
Astrocytoma, Pilocytic 4 | 3,081
Basal cell carcinoma 4 | 54
Big calvaria 4 | 147
Brain disease 4 | 96
Byzanthine arch palate 4 | 194
Carcinoma, squamous cell of head and neck 4 | 31
Cell Transformation, Neoplastic 4 | 97
Colonic Neoplasms 4 | 142
Concave bridge of nose 4 | 195
Curvature of spine 4 | 282
DOID:9917 4 | 31
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Diarrhea 4 | 253
Disease Progression 4 | 136
Downward slant of palpebral fissure 4 | 158
Esophageal carcinoma 4 | 16
Hemangioma 4 | 69
Hemangioma, Cavernous 4 | 20
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Large intestine cancer 4 | 126
Liver cancer 4 | 604
Lymphoid leukemia 4 | 160
Melanocytic nevus 4 | 43
Melanoma 4 | 711
Myopia 4 | 176
Noncancerous mole 4 | 28
Palmoplantar keratosis 4 | 74
Pancreatic Neoplasms 4 | 85
Pectus excavatum 4 | 100
Sebaceous adenoma 4 | 26
Skin cancer 4 | 469
Squamous cell carcinoma of the head and neck 4 | 29
Stomach cancer 4 | 30
Thyroid cancer 4 | 36
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Kinase 7 | 634
Non-IDG 4 | 12,091
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

Compartment GO Term

PTEN phosphatase complex 14 | 14
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
Programmed cell death protein 4 PDCD4 Tchem Non-IDG -2.50341 321.0 599
Vacuole membrane protein 1 VMP1 Tbio Non-IDG -2.49755 302.1 137
Putative microRNA 17 host gene protein MIR17HG Tdark Non-IDG 0.00000 0
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Epidermal growth factor receptor EGFR Tclin Kinase -4.02650 10013.1 6418
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.28550 20244.6 3859
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565