Development Level

Tbio 28 | 11,445
Tchem 7 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
cataract 3 | 92
abnormal heart morphology 2 | 162
decreased circulating insulin ... 2 | 76
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart looping 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small spleen 1 | 19
small testis 1 | 58
vertebral transformation 1 | 12

Disease

ovarian cancer 26 | 8,520
Carcinoma 25 | 11,493
group 3 medulloblastoma 20 | 4,104
Breast cancer 18 | 3,578
atypical teratoid / rhabdoid tumor 18 | 5,112
glioblastoma 18 | 5,792
medulloblastoma, large-cell 18 | 6,241
psoriasis 18 | 6,694
lung cancer 16 | 4,740
ependymoma 15 | 4,679
osteosarcoma 15 | 7,950
primitive neuroectodermal tumor 15 | 3,035
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 13 | 2,951
Cancer 12 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
non-small cell lung cancer 12 | 2,890
ductal carcinoma in situ 11 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
pancreatic cancer 11 | 2,398
Astrocytoma, Pilocytic 10 | 3,081
adrenocortical carcinoma 10 | 1,428
oligodendroglioma 10 | 2,850
breast carcinoma 9 | 1,638
lung adenocarcinoma 9 | 2,716
malignant mesothelioma 9 | 3,232
nasopharyngeal carcinoma 7 | 1,058
Atopic dermatitis 6 | 952
Endometriosis 6 | 540
Kidney cancer 6 | 2,613
astrocytic glioma 6 | 2,597
colon cancer 5 | 1,478
dermatomyositis 5 | 966
interstitial cystitis 5 | 2,312
tuberculosis 5 | 2,010
Dull intelligence 4 | 645
Epilepsy 4 | 792
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Poor school performance 4 | 645
Rheumatoid arthritis 4 | 1,191
Small head 4 | 374
astrocytoma 4 | 1,146
juvenile dermatomyositis 4 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Adenoma 3 | 167
Breast Neoplasms 3 | 445
Diffuse large B-cell lymphoma 3 | 39
Glaucoma 3 | 239
Glioma 3 | 74
Immune system cancer 3 | 140
Lymphoid leukemia 3 | 160
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Pick disease 3 | 1,894
Seizures 3 | 596
Short stature 3 | 531
Waldenstrons macroglobulinemia 3 | 765
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
Acquired metabolic disease 2 | 336
Acquired scoliosis 2 | 281
Arthrogryposis 2 | 54
Barrett's esophagus 2 | 182
Blepharoptosis 2 | 231
Contracture of joint of hand 2 | 30
Curvature of spine 2 | 282
DOID:2627 2 | 94
Dysplastic nevus syndrome 2 | 7
ENSP00000256078 2 | 30
Endometrial Neoplasms 2 | 55
Esophageal carcinoma 2 | 16
Flexion contracture of proximal interphalangeal joint 2 | 75
Head and neck squamous cell carcinoma 2 | 11
Kidney Failure 2 | 111
Liver cancer 2 | 604
Long philtrum 2 | 137
Lupus erythematosus 2 | 57
Lymphoma 2 | 81
MYELODYSPLASTIC SYNDROME 2 | 53
Melanocytic nevus 2 | 43
Mouth Neoplasms 2 | 55
Primary cutaneous T-cell lymphoma 2 | 29
Skin cancer 2 | 469
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
cystic fibrosis 2 | 1,696
cystic fibrosis and chronic rhinosinusitis 2 | 214
medulloblastoma 2 | 720
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 24 | 12,091
Epigenetic 9 | 242
Enzyme 3 | 4,145
Transcription Factor 1 | 1,400

Compartment GO Term

PRC1 complex 37 | 37
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polycomb group RING finger protein 3 PCGF3 Tdark Non-IDG -0.48328 1.97 115
Polycomb group RING finger protein 1 PCGF1 Tbio Non-IDG -0.99091 11.4 101
Chromobox protein homolog 8 CBX8 Tchem Epigenetic -2.27537 183.4 505
Chromobox protein homolog 2 CBX2 Tchem Epigenetic -1.37369 24.3 223
Autism susceptibility gene 2 protein AUTS2 Tbio Non-IDG -1.62719 42.8 79
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Chromosome-associated kinesin KIF4A KIF4A Tbio Non-IDG -1.91717 78.0 157
BCL-6 corepressor BCOR Tbio Non-IDG -2.04681 115.7 157
E3 SUMO-protein ligase CBX4 CBX4 Tchem Epigenetic -1.32793 21.9 353
Polyhomeotic-like protein 2 PHC2 Tbio Non-IDG -2.22805 167.4 82