Development Level

Tbio 75 | 11,445
Tchem 18 | 1,598
Tdark 3 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 9 | 499
abnormal embryo size 3 | 220
decreased circulating glucose ... 3 | 126
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal heart morphology 2 | 162
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased body length 2 | 32
increased bone mineral content 2 | 108
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
abnormal spinal cord morpholog... 1 | 9
abnormal urinary bladder morph... 1 | 11
abnormal vitreous body morphol... 1 | 10
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
edema 1 | 59
enlarged epididymis 1 | 31
hyperactivity 1 | 148
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating sodium l... 1 | 71
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
pallor 1 | 34
shortened RR interval 1 | 17
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 79 | 11,493
ovarian cancer 59 | 8,520
osteosarcoma 55 | 7,950
Cancer 48 | 2,499
medulloblastoma, large-cell 46 | 6,241
psoriasis 45 | 6,694
glioblastoma 41 | 5,792
lung cancer 41 | 4,740
Breast cancer 33 | 3,578
atypical teratoid / rhabdoid tumor 31 | 5,112
adult high grade glioma 26 | 3,801
malignant mesothelioma 25 | 3,232
group 3 medulloblastoma 24 | 4,104
primitive neuroectodermal tumor 24 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Kidney cancer 20 | 2,613
ependymoma 20 | 4,679
pituitary cancer 18 | 1,972
Astrocytoma, Pilocytic 17 | 3,081
Waldenstrons macroglobulinemia 17 | 765
juvenile dermatomyositis 17 | 1,187
non-small cell lung cancer 17 | 2,890
pancreatic cancer 17 | 2,398
subependymal giant cell astrocytoma 17 | 2,287
tuberculosis 17 | 2,010
Intellectual disability 16 | 1,016
Pick disease 16 | 1,894
Rheumatoid arthritis 16 | 1,191
astrocytic glioma 16 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Multiple myeloma 15 | 1,332
diabetes mellitus 15 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
ulcerative colitis 15 | 1,819
oligodendroglioma 14 | 2,850
group 4 medulloblastoma 13 | 1,855
breast carcinoma 12 | 1,638
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Small head 11 | 374
acute quadriplegic myopathy 11 | 1,158
dermatomyositis 11 | 966
invasive ductal carcinoma 11 | 2,951
Autosomal recessive predisposition 10 | 1,442
Prostatic Neoplasms 10 | 495
Short stature 10 | 531
cutaneous lupus erythematosus 10 | 1,057
lung carcinoma 10 | 2,843
Schizophrenia 9 | 1,160
interstitial cystitis 9 | 2,312
lung adenocarcinoma 9 | 2,716
pediatric high grade glioma 9 | 1,064
primary Sjogren syndrome 9 | 735
Amyotrophic lateral sclerosis 8 | 451
Breast Neoplasms 8 | 445
Mammary Neoplasms 8 | 425
Parkinson's disease 8 | 392
acute myeloid leukemia 8 | 783
adrenocortical carcinoma 8 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Carcinoma, Hepatocellular 7 | 228
Cognitive delay 7 | 608
Epilepsy 7 | 792
Global developmental delay 7 | 608
Hypoplastic mandible condyle 7 | 275
Liver carcinoma 7 | 240
Lymphoma 7 | 81
Mandibular hypoplasia 7 | 275
Mental and motor retardation 7 | 608
Micrognathism 7 | 275
Multiple Sclerosis 7 | 540
Obesity 7 | 678
Pancreatic Neoplasm 7 | 85
Thrombocytopenia 7 | 197
colon cancer 7 | 1,478
medulloblastoma 7 | 720
Ataxia telangiectasia 6 | 34
Chronic Lymphocytic Leukemia 6 | 262
Cleft Palate 6 | 271
Glioma 6 | 74
Hereditary Breast and Ovarian Cancer Syndrome 6 | 14
Leukemia 6 | 104
Liver cancer 6 | 604
Muscle hypotonia 6 | 571
Nijmegen breakage syndrome 6 | 24
Pancreatic Neoplasms 6 | 85
Renal Cell Carcinoma 6 | 214
aldosterone-producing adenoma 6 | 665
astrocytoma 6 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
cystic fibrosis 6 | 1,696
ductal carcinoma in situ 6 | 1,745
non primary Sjogren syndrome sicca 6 | 891
progressive supranuclear palsy 6 | 676
gastric carcinoma 5 | 807
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074

Tissue

Endocrine System 98 | 18,159
Blood and immune system 96 | 16,909
Digestive Tract 96 | 17,369
Female tissues 96 | 17,400
Nervous System 96 | 16,725
Liver and Pancreas 95 | 16,750
Male tissues 95 | 17,142
Respiratory system 95 | 16,393
Skin and soft tissues 95 | 17,230
Urinary Tract 95 | 16,678
Cardiovascular System 94 | 15,192

Target Family

Non-IDG 51 | 12,091
Enzyme 17 | 4,145
Transcription Factor 15 | 1,400
Kinase 8 | 634
TF/Epigenetic 3 | 38
Epigenetic 2 | 242
Nuclear Receptor 2 | 48

Compartment GO Term

PML body 98 | 98
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Regulator of G-protein signaling 14 RGS14 Tbio Non-IDG -1.61170 43.9 233
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
E3 SUMO-protein ligase ZNF451 ZNF451 Tbio Transcription Factor -2.42090 254.4 71
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 ASZ1 Tbio Non-IDG -2.81661 644.9 107
PML-RARA-regulated adapter molecule 1 PRAM1 Tbio Non-IDG -2.18597 152.1 104
DNA topoisomerase 3-alpha TOP3A Tbio Enzyme -2.77897 560.7 45
Nuclear receptor subfamily 2 group C member 1 NR2C1 Tbio Nuclear Receptor -1.39182 24.4 294
Structural maintenance of chromosomes protein 6 SMC6 Tbio Non-IDG -1.42371 20.0 115
A-kinase anchor protein 8-like AKAP8L Tbio Enzyme -1.03730 13.2 140