Development Level

Tbio 71 | 10,625
Tchem 20 | 1,890
Tdark 3 | 7,003
Tclin 2 | 602

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 6 | 260
increased or absent threshold ... 3 | 128
abnormal bone structure 2 | 131
abnormal maxilla morphology 2 | 16
abnormal retinal pigmentation 2 | 61
abnormal snout morphology 2 | 18
abnormal tooth morphology 2 | 24
decreased body length 2 | 108
decreased circulating glucose ... 2 | 121
decreased rib number 2 | 59
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
abnormal behavior 1 | 226
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal social-conspecific in... 1 | 3
abnormal vitreous body morphol... 1 | 7
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating fructosa... 1 | 31
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased respiratory quotient 1 | 12
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hyperactivity 1 | 108
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased heart weight 1 | 37
increased kidney weight 1 | 4
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
oligodactyly 1 | 14
tremors 1 | 34

Disease

ovarian cancer 56 | 8,491
osteosarcoma 53 | 7,933
Cancer 46 | 2,346
medulloblastoma, large-cell 45 | 6,234
psoriasis 44 | 6,685
glioblastoma 39 | 5,572
lung cancer 38 | 4,473
Breast cancer 27 | 3,098
atypical teratoid / rhabdoid tumor 27 | 4,369
malignant mesothelioma 25 | 3,163
primitive neuroectodermal tumor 23 | 3,031
adult high grade glioma 21 | 2,148
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
Carcinoma 18 | 2,147
pituitary cancer 17 | 1,972
Rheumatoid Arthritis 16 | 1,170
Waldenstrons macroglobulinemia 16 | 764
non-small cell lung cancer 16 | 2,798
Pick disease 15 | 1,893
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
juvenile dermatomyositis 15 | 1,189
pilocytic astrocytoma 15 | 3,086
subependymal giant cell astrocytoma 15 | 2,287
ulcerative colitis 15 | 2,087
Multiple myeloma 14 | 1,327
diabetes mellitus 14 | 1,663
pancreatic cancer 14 | 2,300
astrocytic glioma 13 | 2,241
ependymoma 13 | 2,514
oligodendroglioma 13 | 2,849
pediatric high grade glioma 13 | 2,712
group 3 medulloblastoma 12 | 2,254
medulloblastoma 12 | 1,524
tuberculosis 12 | 1,563
group 4 medulloblastoma 11 | 1,875
invasive ductal carcinoma 11 | 2,950
acute quadriplegic myopathy 10 | 1,157
dermatomyositis 10 | 966
breast carcinoma 9 | 1,614
lung carcinoma 9 | 2,844
primary Sjogren syndrome 9 | 788
Amyotrophic Lateral Sclerosis 8 | 432
Intellectual disability 8 | 573
Mammary Neoplasms 8 | 410
Prostatic Neoplasms 8 | 471
acute myeloid leukemia 8 | 785
adrenocortical carcinoma 8 | 1,427
astrocytoma 8 | 1,493
atypical teratoid/rhabdoid tumor 8 | 1,095
cutaneous lupus erythematosus 8 | 1,056
interstitial cystitis 8 | 2,299
lung adenocarcinoma 8 | 2,714
sonic hedgehog group medulloblastoma 8 | 1,482
Nijmegen breakage syndrome 7 | 23
Parkinson's disease 7 | 364
colon cancer 7 | 1,475
posterior fossa group B ependymoma 7 | 1,530
tuberculosis and treatment for 6 months 7 | 686
Ataxia telangiectasia 6 | 32
Bloom syndrome 6 | 30
Hereditary Breast and Ovarian Cancer Syndrome 6 | 14
Liver carcinoma 6 | 217
Neoplastic Syndromes, Hereditary 6 | 48
Pancreatic Neoplasm 6 | 79
Renal Cell Carcinoma 6 | 199
ductal carcinoma in situ 6 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
primary pancreatic ductal adenocarcinoma 6 | 1,271
progressive supranuclear palsy 6 | 674
Adenocarcinoma 5 | 115
Anemia 5 | 252
Atopic dermatitis 5 | 944
Diabetes Mellitus, Non-Insulin-Dependent 5 | 161
Endometriosis 5 | 535
Malignant neoplasm of breast 5 | 63
Malignant neoplasm of prostate 5 | 67
Metabolic syndrome X 5 | 155
Multiple Sclerosis 5 | 498
Neurodegenerative disease 5 | 383
Obesity 5 | 616
Prostate cancer 5 | 172
aldosterone-producing adenoma 5 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
cystic fibrosis 5 | 1,670
gastric carcinoma 5 | 832
inflammatory breast cancer 5 | 404
non primary Sjogren syndrome sicca 5 | 840
non-small cell lung carcinoma 5 | 413
posterior fossa group A ependymoma 5 | 1,511
spina bifida 5 | 1,064
Alzheimer's disease 4 | 644
Crohn's disease 4 | 304
Vascular disease 4 | 281
active Crohn's disease 4 | 918
chronic lymphocytic leukemia 4 | 244
chronic lymphosyte leukemia 4 | 232
hepatocellular carcinoma 4 | 550
nasopharyngeal carcinoma 4 | 1,056
pancreatic carcinoma 4 | 567

Tissue

Blood and immune system 96 | 17,994
Female tissues 96 | 18,646
Male tissues 96 | 17,968
Nervous System 96 | 18,560
Digestive Tract 95 | 18,472
Endocrine System 95 | 18,511
Liver and Pancreas 95 | 18,135
Cardiovascular System 94 | 17,957
Urinary Tract 94 | 18,443
Respiratory system 93 | 17,483
Skin and soft tissues 93 | 18,114

Target Family

Non-IDG 50 | 11,969
Enzyme 17 | 4,146
Transcription Factor 15 | 1,400
Kinase 8 | 634
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

Compartment GO Term

PML body 96 | 96
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein RFP TRIM27 Tbio Non-IDG -1.50884 32.8 154
DNA-binding protein SATB1 SATB1 Tbio Transcription Factor -2.24334 197.9 293
E3 ubiquitin-protein ligase Arkadia RNF111 Tbio Enzyme -1.35799 23.9 89
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.69416 474.2 685
Structural maintenance of chromosomes protein 6 SMC6 Tbio Non-IDG -1.40489 19.9 106
A-kinase anchor protein 8-like AKAP8L Tbio Enzyme -1.01650 13.0 125
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.26734 207.5 1100
Death domain-associated protein 6 DAXX Tbio Non-IDG -2.30299 222.3 672
Transcription factor Sp3 SP3 Tbio Transcription Factor -2.48548 281.9 319
Eukaryotic translation initiation factor 4E transporter EIF4ENIF1 Tbio Non-IDG -1.54411 31.2 206