Development Level

Tbio 45 | 11,178
Tchem 34 | 1,885
Tclin 16 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal heart morphology 5 | 162
preweaning lethality, incomple... 5 | 499
abnormal embryo size 4 | 220
enlarged heart 3 | 210
abnormal embryo turning 2 | 31
abnormal lens morphology 2 | 81
abnormal pharyngeal arch morph... 2 | 8
cataract 2 | 92
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased total body fat amoun... 2 | 134
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal blood vessel morpholo... 1 | 5
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal coat- hair morphology 1 | 19
abnormal embryo development 1 | 7
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hair texture 1 | 4
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
mammalian phenotype 1 | 17
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24
urinary bladder obstruction 1 | 4

Disease

Cancer 77 | 2,388
ovarian cancer 66 | 8,297
Carcinoma 62 | 11,192
lung cancer 58 | 4,607
psoriasis 56 | 6,514
glioblastoma 55 | 5,635
osteosarcoma 51 | 7,766
malignant mesothelioma 48 | 3,135
Breast cancer 45 | 3,469
medulloblastoma, large-cell 44 | 6,086
non-small cell lung cancer 40 | 2,799
atypical teratoid / rhabdoid tumor 39 | 4,971
group 3 medulloblastoma 39 | 4,002
lung adenocarcinoma 38 | 2,627
invasive ductal carcinoma 35 | 2,867
adult high grade glioma 34 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,204
diabetes mellitus 33 | 1,683
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,902
Breast Neoplasms 31 | 423
Mammary Neoplasms 31 | 403
ependymoma 31 | 4,559
primitive neuroectodermal tumor 31 | 2,957
Schizophrenia 29 | 1,136
adrenocortical carcinoma 29 | 1,385
Prostatic Neoplasms 28 | 472
Stomach Neoplasms 28 | 287
Adenoma 26 | 159
Kidney disease 25 | 411
ductal carcinoma in situ 25 | 1,686
Adenocarcinoma 24 | 116
Lung Neoplasms 24 | 217
breast carcinoma 24 | 1,589
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,872
nasopharyngeal carcinoma 24 | 1,024
pancreatic cancer 24 | 2,322
ulcerative colitis 24 | 1,765
Endometriosis 23 | 521
oligodendroglioma 23 | 2,768
Carcinoma, Hepatocellular 22 | 217
Heart disease 22 | 288
Liver carcinoma 22 | 229
Astrocytoma, Pilocytic 21 | 3,006
Colonic Neoplasms 21 | 133
Liver disease 20 | 227
Neoplasm Metastasis 20 | 160
colon cancer 20 | 1,428
interstitial cystitis 20 | 2,237
Vascular disease 19 | 294
pituitary cancer 19 | 1,915
Depressive disorder 18 | 401
Kidney cancer 18 | 2,548
Neoplasm Invasiveness 18 | 151
Obesity 18 | 655
Squamous cell carcinoma 18 | 125
Alzheimer's disease 17 | 640
Carcinoma, Squamous Cell 17 | 107
Colorectal Neoplasms 17 | 235
Liver Cirrhosis, Experimental 17 | 733
Liver Neoplasms, Experimental 17 | 58
lung carcinoma 17 | 2,755
tuberculosis 17 | 1,963
Asthma 16 | 370
Bladder Neoplasm 16 | 106
Cerebrovascular disease 16 | 223
Hypertension 16 | 372
Lung disease 16 | 135
Melanoma 16 | 689
Ovarian Neoplasms 16 | 96
Urinary Bladder Neoplasms 16 | 108
astrocytoma 16 | 1,113
ovarian neoplasm 16 | 93
subependymal giant cell astrocytoma 16 | 2,230
Atherosclerosis 15 | 276
Toxic encephalopathy 15 | 139
astrocytic glioma 15 | 2,530
cystic fibrosis 15 | 1,629
Anemia 14 | 353
Atopic dermatitis 14 | 915
Autosomal recessive predisposition 14 | 1,407
Cell Transformation, Neoplastic 14 | 90
Neoplastic Cell Transformation 14 | 83
medulloblastoma 14 | 702
Arthritis 13 | 276
Bipolar Disorder 13 | 646
Brain Ischemia 13 | 107
Coronary artery disease 13 | 253
Hyperglycemia 13 | 134
Major Depressive Disorder 13 | 293
Mammary Neoplasms, Experimental 13 | 147
Pancreatic Neoplasm 13 | 82
Pancreatic Neoplasms 13 | 82
acute quadriplegic myopathy 13 | 1,133
Inflammatory bowel disease 12 | 148
Mental Depression 12 | 325
Myocardial Ischemia 12 | 162
Parkinson's disease 12 | 378
Reperfusion Injury 12 | 84
Rheumatoid arthritis 12 | 1,156
Unipolar Depression 12 | 244

Tissue

Blood and immune system 93 | 16,909
Digestive Tract 93 | 17,369
Endocrine System 92 | 18,159
Female tissues 92 | 17,400
Male tissues 92 | 17,142
Nervous System 92 | 16,725
Respiratory system 92 | 16,393
Skin and soft tissues 92 | 17,230
Urinary Tract 92 | 16,678
Liver and Pancreas 91 | 16,750
Cardiovascular System 87 | 15,192

Target Family

Non-IDG 49 | 12,091
Enzyme 23 | 4,145
Kinase 13 | 634
Transcription Factor 4 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 3 | 48

Compartment GO Term

PCNA complex 95 | 95
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Keratin, type I cytoskeletal 19 KRT19 Tbio Non-IDG -3.23530 1627.1 1789
N-lysine methyltransferase KMT5A KMT5A Tchem Epigenetic -1.89071 71.7 420
Progesterone receptor PGR Tclin Nuclear Receptor -3.94412 7951.2 2098
DNA repair protein REV1 REV1 Tbio Non-IDG -2.43956 286.1 101
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982
DNA repair protein XRCC1 XRCC1 Tbio Non-IDG -2.99664 1034.1 418
E3 ubiquitin-protein ligase RAD18 RAD18 Tbio Enzyme -2.22905 169.1 271
Hematopoietic prostaglandin D synthase HPGDS Tchem Enzyme -3.74110 4712.9 77
DNA nucleotidylexotransferase DNTT Tchem Enzyme -3.41739 1725.2 436
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125