Development Level

Tbio 82 | 11,445
Tdark 9 | 6,588
Tchem 3 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased grip strength 2 | 116
embryonic lethality prior to o... 2 | 239
increased grip strength 2 | 41
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal urinary bladder morph... 1 | 11
abnormal vitreous body morphol... 1 | 10
absent spleen 1 | 3
aorta dilation 1 | 3
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hyperactivity 1 | 148
increased body length 1 | 32
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
male infertility 1 | 123
pallor 1 | 34
prenatal lethality 1 | 28
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 58 | 11,493
osteosarcoma 56 | 7,950
ovarian cancer 54 | 8,520
atypical teratoid / rhabdoid tumor 38 | 5,112
glioblastoma 34 | 5,792
medulloblastoma, large-cell 33 | 6,241
lung cancer 31 | 4,740
psoriasis 30 | 6,694
group 3 medulloblastoma 25 | 4,104
primitive neuroectodermal tumor 22 | 3,035
Breast cancer 21 | 3,578
Kidney cancer 21 | 2,613
ependymoma 21 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
malignant mesothelioma 17 | 3,232
Pick disease 16 | 1,894
adult high grade glioma 16 | 3,801
group 4 medulloblastoma 15 | 1,855
oligodendroglioma 15 | 2,850
subependymal giant cell astrocytoma 15 | 2,287
Cancer 14 | 2,499
acute quadriplegic myopathy 14 | 1,158
juvenile dermatomyositis 14 | 1,187
pancreatic cancer 14 | 2,398
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
lung adenocarcinoma 13 | 2,716
invasive ductal carcinoma 12 | 2,951
spina bifida 12 | 1,074
Amyotrophic lateral sclerosis 11 | 451
Astrocytoma, Pilocytic 11 | 3,081
Multiple myeloma 11 | 1,332
Waldenstrons macroglobulinemia 11 | 765
astrocytoma 11 | 1,146
dermatomyositis 11 | 966
tuberculosis 11 | 2,010
non-small cell lung cancer 10 | 2,890
pituitary cancer 10 | 1,972
breast carcinoma 9 | 1,638
lung carcinoma 9 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Liver cancer 8 | 604
progressive supranuclear palsy 8 | 676
Rheumatoid arthritis 7 | 1,191
adrenocortical carcinoma 7 | 1,428
medulloblastoma 7 | 720
primary Sjogren syndrome 7 | 735
primary pancreatic ductal adenocarcinoma 7 | 1,109
ulcerative colitis 7 | 1,819
aldosterone-producing adenoma 6 | 665
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
hepatocellular carcinoma 6 | 547
Alzheimer's disease 5 | 658
Atopic dermatitis 5 | 952
Neurodegenerative disease 5 | 414
Polycystic ovary syndrome 5 | 360
Primary biliary cirrhosis 5 | 51
active Crohn's disease 5 | 922
colon cancer 5 | 1,478
ductal carcinoma in situ 5 | 1,745
pediatric high grade glioma 5 | 1,064
Acquired immunodeficiency syndrome 4 | 197
Autosomal recessive predisposition 4 | 1,442
HIV Infections 4 | 102
Schizophrenia 4 | 1,160
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
relapsing-remitting multiple sclerosis 4 | 18
tuberculosis and treatment for 6 months 4 | 409
Bipolar Disorder 3 | 666
Cardiovascular system disease 3 | 246
Celiac disease 3 | 116
Depressive disorder 3 | 409
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Dysarthria 3 | 192
Infertility 3 | 188
Neoplasm Invasiveness 3 | 161
Premature ovarian failure 3 | 65
Spinocerebellar ataxia type 2 3 | 23
atypical teratoid/rhabdoid tumor 3 | 357
gastric carcinoma 3 | 807
inflammatory breast cancer 3 | 286
sarcoidosis 3 | 370
tuberculosis and treatment for 3 months 3 | 179
urothelial carcinoma 3 | 318
Endometrial cancer 2 | 311
Essential Hypertension 2 | 94
Multiple Sclerosis 2 | 540
Parkinson's disease 2 | 392
Substance-Related Disorders 2 | 115
posterior fossa group B ependymoma 2 | 416
substance-related disorder 2 | 162

Tissue

Endocrine System 94 | 18,159
Male tissues 93 | 17,142
Nervous System 93 | 16,725
Blood and immune system 92 | 16,909
Female tissues 92 | 17,400
Respiratory system 92 | 16,393
Digestive Tract 91 | 17,369
Liver and Pancreas 91 | 16,750
Skin and soft tissues 91 | 17,230
Urinary Tract 91 | 16,678
Cardiovascular System 89 | 15,192

Target Family

Non-IDG 70 | 12,091
Enzyme 22 | 4,145
Transcription Factor 2 | 1,400
Kinase 1 | 634

Compartment GO Term

P-body 95 | 95
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248
Endoribonuclease Dicer DICER1 Tbio Enzyme -3.34177 2054.3 327
E3 ubiquitin-protein ligase TRIM21 TRIM21 Tbio Enzyme -3.03008 1099.3 268
Eukaryotic translation initiation factor 4E EIF4E Tchem Non-IDG -3.01611 1064.1 712
Protein argonaute-2 AGO2 Tbio Non-IDG -2.97243 867.1 202
Nucleolysin TIA-1 isoform p40 TIA1 Tbio Non-IDG -2.86461 714.2 314
CCR4-NOT transcription complex subunit 8 CNOT8 Tbio Non-IDG -2.83783 687.5 209
DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G Tbio Non-IDG -2.78510 662.2 477
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.78728 635.1 766
CCR4-NOT transcription complex subunit 2 CNOT2 Tbio Non-IDG -2.83887 627.5 303