Development Level

Tbio 101 | 11,445
Tclin 71 | 613
Tchem 49 | 1,598
Tdark 4 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 27 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 8 | 278
decreased vertical activity 6 | 208
cataract 5 | 92
decreased erythrocyte cell num... 5 | 62
decreased total body fat amoun... 5 | 207
increased lean body mass 5 | 172
abnormal embryo size 4 | 220
embryonic growth retardation 4 | 106
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral content 3 | 151
decreased circulating amylase ... 3 | 28
decreased heart weight 3 | 27
decreased lean body mass 3 | 135
increased bone mineral content 3 | 108
increased circulating calcium ... 3 | 34
increased total body fat amoun... 3 | 134
abnormal femur morphology 2 | 14
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased lactate dehydrogenas... 2 | 16
decreased lymphocyte cell numb... 2 | 83
decreased mean platelet volume 2 | 25
decreased total retina thickne... 2 | 17
hypoactivity 2 | 132
increased circulating LDL chol... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
increased neutrophil cell numb... 2 | 46
pallor 2 | 34
persistence of hyaloid vascula... 2 | 33
prolonged ST segment 2 | 36
thrombocytopenia 2 | 56
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal hair growth 1 | 10
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal joint morphology 1 | 23
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic disc morphology 1 | 10
abnormal retinal inner nuclear... 1 | 8
abnormal sensory capabilities-... 1 | 8
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vitelline vasculature... 1 | 6
abnormal vitreous body morphol... 1 | 10
absent pinna reflex 1 | 23
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased red blood cell distr... 1 | 41
enlarged epididymis 1 | 31
enlarged uterus 1 | 11
hemorrhage 1 | 23
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
small superior vagus ganglion 1 | 74
small testis 1 | 58
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

ovarian cancer 125 | 8,520
Carcinoma 111 | 11,493
Cancer 98 | 2,499
psoriasis 95 | 6,694
osteosarcoma 91 | 7,950
diabetes mellitus 87 | 1,728
lung cancer 85 | 4,740
glioblastoma 79 | 5,792
Autosomal recessive predisposition 68 | 1,442
medulloblastoma, large-cell 65 | 6,241
Multiple myeloma 62 | 1,332
Kidney disease 58 | 430
ependymoma 56 | 4,679
atypical teratoid / rhabdoid tumor 55 | 5,112
pancreatic ductal adenocarcinoma liver metastasis 55 | 1,962
Hypertension 54 | 396
Obesity 52 | 678
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,291
lung adenocarcinoma 50 | 2,716
non-small cell lung cancer 50 | 2,890
Atherosclerosis 49 | 291
Diabetes mellitus type 2 49 | 69
Treatment Refractory Type 2 Diabetes Mellitus 48 | 53
Schizophrenia 47 | 1,160
malignant mesothelioma 46 | 3,232
Breast cancer 45 | 3,578
tuberculosis 45 | 2,010
Heart disease 44 | 306
Seizures 44 | 596
lung carcinoma 44 | 2,843
Hypertensive disease 43 | 292
invasive ductal carcinoma 43 | 2,951
ulcerative colitis 43 | 1,819
Heart failure 42 | 162
adult high grade glioma 42 | 3,801
Epilepsy 41 | 792
Alzheimer's disease 40 | 658
Cerebellar Ataxia 40 | 304
pancreatic cancer 39 | 2,398
Asthma 38 | 385
Cerebrovascular disease 38 | 238
Toxic encephalopathy 38 | 141
interstitial cystitis 38 | 2,312
Arthritis 37 | 290
group 3 medulloblastoma 37 | 4,104
Leigh disease 36 | 100
astrocytic glioma 36 | 2,597
cystic fibrosis 36 | 1,696
Acidosis, Lactic 35 | 97
Hyperglycemia 35 | 137
Muscle hypotonia 35 | 571
Astrocytoma, Pilocytic 34 | 3,081
Brain Ischemia 34 | 110
Coronary artery disease 34 | 268
Lactic acidemia 34 | 95
Mitochondrial complex I deficiency 34 | 46
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
oligodendroglioma 34 | 2,850
Vascular disease 33 | 319
Bipolar Disorder 32 | 666
Cognitive delay 32 | 608
Diabetes Mellitus, Experimental 32 | 108
Global developmental delay 32 | 608
Liver disease 32 | 237
Mental and motor retardation 32 | 608
Prostatic Neoplasms 32 | 495
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
Anemia 31 | 365
Depressive disorder 31 | 409
Stomach Neoplasms 31 | 300
Intellectual disability 30 | 1,016
Lung disease 30 | 142
Blepharoptosis 29 | 231
Hypoglycemia 29 | 152
Parkinson's disease 29 | 392
acute quadriplegic myopathy 29 | 1,158
adrenocortical carcinoma 29 | 1,428
primitive neuroectodermal tumor 29 | 3,035
Brain disease 28 | 96
Neurodegenerative disease 28 | 414
Rheumatoid arthritis 28 | 1,191
Carcinoma, Hepatocellular 27 | 228
Dull intelligence 27 | 645
Liver carcinoma 27 | 240
Low intelligence 27 | 645
Mental Retardation 27 | 645
Mental deficiency 27 | 645
Poor school performance 27 | 645
Waldenstrons macroglobulinemia 27 | 765
breast carcinoma 27 | 1,638
Diabetes Mellitus, Non-Insulin-Dependent 26 | 145
Hyperreflexia 26 | 209
Liver Cirrhosis, Experimental 26 | 769
Reperfusion Injury 26 | 86
astrocytoma 26 | 1,146
Breast Neoplasms 25 | 445
Dystonia 25 | 164
Mammary Neoplasms 25 | 425
Inflammatory bowel disease 24 | 151
Osteoporosis 24 | 363

Tissue

Endocrine System 223 | 18,159
Digestive Tract 222 | 17,369
Urinary Tract 222 | 16,678
Blood and immune system 221 | 16,909
Female tissues 221 | 17,400
Liver and Pancreas 221 | 16,750
Skin and soft tissues 221 | 17,230
Male tissues 220 | 17,142
Nervous System 217 | 16,725
Respiratory system 216 | 16,393
Cardiovascular System 205 | 15,192

Target Family

Enzyme 136 | 4,145
Non-IDG 63 | 12,091
Kinase 10 | 634
Transcription Factor 7 | 1,400
Transporter 3 | 473
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
GPCR 1 | 408
Ion Channel 1 | 344

Compartment GO Term

Oxidoreductase complex 225 | 225
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 Tclin Enzyme -0.62794 3.79 65
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 Tclin Enzyme -2.43529 263.5 165
2-oxoglutarate dehydrogenase-like, mitochondrial OGDHL Tbio Enzyme -0.59292 3.63 46
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 Tclin Enzyme -2.97252 871.7 197
Cytochrome b-c1 complex subunit 1, mitochondrial UQCRC1 Tbio Enzyme -1.46124 30.0 217
NAD(P) transhydrogenase, mitochondrial NNT Tbio Enzyme -2.49624 309.2 112
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC Tbio Enzyme -2.73791 419.9 129
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Serum albumin ALB Tchem Non-IDG -5.01233 98804.9 2101