Development Level

Tbio 166 | 11,445
Tchem 41 | 1,598
Tclin 15 | 613
Tdark 15 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 14 | 979
decreased vertical activity 9 | 208
hyperactivity 8 | 148
abnormal behavior 7 | 298
decreased body weight 6 | 161
abnormal bone structure 5 | 187
decreased bone mineral content 5 | 151
decreased bone mineral density 5 | 126
decreased lean body mass 5 | 135
hypoactivity 5 | 132
preweaning lethality, incomple... 5 | 499
abnormal lens morphology 4 | 81
abnormal sleep behavior 4 | 70
cataract 4 | 92
decreased body length 4 | 101
decreased heart weight 4 | 27
increased mean corpuscular hem... 4 | 96
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
increased circulating bilirubi... 3 | 16
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
small superior vagus ganglion 3 | 74
thrombocytopenia 3 | 56
abnormal cranium morphology 2 | 36
abnormal epididymis morphology 2 | 42
abnormal skin morphology 2 | 50
abnormal tibia morphology 2 | 14
abnormal vibrissa morphology 2 | 25
decreased circulating aspartat... 2 | 34
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased startle reflex 2 | 75
edema 2 | 59
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
increased bone mineral content 2 | 108
increased heart rate 2 | 23
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 36
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vitreous body morphol... 1 | 10
brachydactyly 1 | 19
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased total retina thickne... 1 | 17
enlarged uterus 1 | 11
female infertility 1 | 60
hemorrhage 1 | 23
hydrometra 1 | 53
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating lipase l... 1 | 3
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
shortened RR interval 1 | 17
small adrenal glands 1 | 16
small kidney 1 | 16
small spleen 1 | 19
small thymus 1 | 16
syndactyly 1 | 23

Disease

ovarian cancer 129 | 8,520
Carcinoma 127 | 11,493
osteosarcoma 106 | 7,950
psoriasis 94 | 6,694
medulloblastoma, large-cell 93 | 6,241
lung cancer 92 | 4,740
glioblastoma 81 | 5,792
atypical teratoid / rhabdoid tumor 74 | 5,112
ependymoma 69 | 4,679
malignant mesothelioma 59 | 3,232
Cancer 57 | 2,499
adult high grade glioma 51 | 3,801
invasive ductal carcinoma 51 | 2,951
Astrocytoma, Pilocytic 49 | 3,081
tuberculosis 48 | 2,010
Breast cancer 47 | 3,578
group 3 medulloblastoma 47 | 4,104
non-small cell lung cancer 45 | 2,890
diabetes mellitus 43 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,291
lung adenocarcinoma 43 | 2,716
pancreatic cancer 41 | 2,398
oligodendroglioma 40 | 2,850
astrocytic glioma 38 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,962
ulcerative colitis 38 | 1,819
ductal carcinoma in situ 35 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,955
lung carcinoma 35 | 2,843
primitive neuroectodermal tumor 35 | 3,035
cystic fibrosis 34 | 1,696
Autosomal recessive predisposition 33 | 1,442
Pick disease 31 | 1,894
Multiple myeloma 30 | 1,332
interstitial cystitis 30 | 2,312
breast carcinoma 29 | 1,638
group 4 medulloblastoma 29 | 1,855
Alzheimer's disease 28 | 658
Obesity 27 | 678
pituitary cancer 26 | 1,972
subependymal giant cell astrocytoma 26 | 2,287
Kidney cancer 25 | 2,613
Neurodegenerative disease 25 | 414
Schizophrenia 24 | 1,160
dermatomyositis 24 | 966
Rheumatoid arthritis 23 | 1,191
colon cancer 23 | 1,478
cutaneous lupus erythematosus 19 | 1,057
pediatric high grade glioma 19 | 1,064
Cerebrovascular disease 18 | 238
Multiple Sclerosis 18 | 540
Waldenstrons macroglobulinemia 18 | 765
juvenile dermatomyositis 18 | 1,187
Muscle hypotonia 17 | 571
Toxic encephalopathy 17 | 141
Atopic dermatitis 16 | 952
Bipolar Disorder 16 | 666
Diarrhea 16 | 253
Kidney disease 16 | 430
acute quadriplegic myopathy 16 | 1,158
non primary Sjogren syndrome sicca 16 | 891
Breast Neoplasms 15 | 445
Coronary artery disease 15 | 268
Epilepsy 15 | 792
Liver Cirrhosis, Experimental 15 | 769
Mammary Neoplasms 15 | 425
Neuropathy 15 | 261
Parkinson's disease 15 | 392
acute myeloid leukemia 15 | 783
adrenocortical carcinoma 15 | 1,428
aldosterone-producing adenoma 15 | 665
esophageal adenocarcinoma 15 | 737
Anemia 14 | 365
Asthma 14 | 385
Atherosclerosis 14 | 291
Hypertension 14 | 396
Melanoma 14 | 711
astrocytoma 14 | 1,146
primary pancreatic ductal adenocarcinoma 14 | 1,109
progressive supranuclear palsy 14 | 676
Brain disease 13 | 96
Down syndrome 13 | 499
Endometriosis 13 | 540
Influenza 13 | 142
Intellectual disability 13 | 1,016
active Crohn's disease 13 | 922
active ulcerative colitis 13 | 764
gastric carcinoma 13 | 807
primary Sjogren syndrome 13 | 735
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Heart disease 12 | 306
Mental and motor retardation 12 | 608
Optic Atrophy 12 | 242
Polycystic ovary syndrome 12 | 360
Seizures 12 | 596
Vascular disease 12 | 319
hereditary spastic paraplegia 12 | 318
medulloblastoma 12 | 720

Tissue

Endocrine System 233 | 18,159
Female tissues 230 | 17,400
Digestive Tract 229 | 17,369
Blood and immune system 228 | 16,909
Liver and Pancreas 228 | 16,750
Male tissues 228 | 17,142
Skin and soft tissues 228 | 17,230
Urinary Tract 227 | 16,678
Respiratory system 224 | 16,393
Nervous System 223 | 16,725
Cardiovascular System 218 | 15,192

Target Family

Non-IDG 138 | 12,091
Enzyme 65 | 4,145
Kinase 17 | 634
Transporter 7 | 473
GPCR 3 | 408
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

Compartment GO Term

Outer membrane 237 | 237
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hexokinase-2 HK2 Tchem Kinase -2.64934 432.5 446
Rab11 family-interacting protein 5 RAB11FIP5 Tbio Non-IDG -1.52843 34.5 62
Nesprin-3 SYNE3 Tbio Non-IDG -0.90535 8.77 107
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
UDP-glucuronosyltransferase 2B28 UGT2B28 Tbio Enzyme -0.88835 8.45 45
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
Sorting and assembly machinery component 50 homolog SAMM50 Tbio Non-IDG -2.09079 120.9 124
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80