Development Level

Tbio 140 | 10,625
Tchem 47 | 1,890
Tdark 18 | 7,003
Tclin 13 | 602

IMPC Phenotype

decreased body weight 6 | 174
decreased lean body mass 6 | 195
preweaning lethality, complete... 6 | 633
decreased heart weight 5 | 44
hypoactivity 5 | 89
decreased body length 4 | 108
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
increased mean corpuscular hem... 4 | 93
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
thrombocytopenia 3 | 46
abnormal lens morphology 2 | 73
abnormal sleep behavior 2 | 63
abnormal tibia morphology 2 | 14
decreased circulating LDL chol... 2 | 37
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased mean corpuscular hem... 2 | 34
decreased total retina thickne... 2 | 20
decreased vertical activity 2 | 22
embryonic lethality prior to o... 2 | 148
hyperactivity 2 | 108
immune system phenotype 2 | 17
increased circulating bilirubi... 2 | 16
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased heart weight 2 | 37
short tibia 2 | 82
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coat- hair morphology 1 | 18
abnormal cranium morphology 1 | 32
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal tail morphology 1 | 17
abnormal vertebrae morphology 1 | 14
absent vibrissae 1 | 14
cataract 1 | 26
convulsive seizures 1 | 11
corneal opacity 1 | 25
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
edema 1 | 11
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hemorrhage 1 | 12
hydrometra 1 | 13
hydrops fetalis 1 | 22
increased body length 1 | 20
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased erythrocyte cell num... 1 | 26
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased red blood cell distr... 1 | 21
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
microphthalmia 1 | 15
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
respiratory system phenotype 1 | 2
shortened PQ interval 1 | 6
small heart 1 | 8
small kidney 1 | 10
small spleen 1 | 11

Disease

ovarian cancer 121 | 8,491
osteosarcoma 100 | 7,933
medulloblastoma, large-cell 91 | 6,234
psoriasis 88 | 6,685
lung cancer 84 | 4,473
glioblastoma 79 | 5,572
atypical teratoid / rhabdoid tumor 64 | 4,369
Cancer 53 | 2,346
malignant mesothelioma 52 | 3,163
invasive ductal carcinoma 49 | 2,950
pilocytic astrocytoma 48 | 3,086
ulcerative colitis 44 | 2,087
non-small cell lung cancer 41 | 2,798
diabetes mellitus 40 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,988
lung adenocarcinoma 40 | 2,714
Breast cancer 39 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,289
pancreatic cancer 39 | 2,300
oligodendroglioma 38 | 2,849
pediatric high grade glioma 37 | 2,712
primitive neuroectodermal tumor 37 | 3,031
lung carcinoma 36 | 2,844
ependymoma 34 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,795
astrocytic glioma 33 | 2,241
ductal carcinoma in situ 32 | 1,745
Pick disease 31 | 1,893
interstitial cystitis 31 | 2,299
tuberculosis 31 | 1,563
adult high grade glioma 30 | 2,148
cystic fibrosis 30 | 1,670
breast carcinoma 29 | 1,614
Alzheimer's disease 28 | 644
Multiple myeloma 28 | 1,327
group 4 medulloblastoma 26 | 1,875
pituitary cancer 26 | 1,972
posterior fossa group A ependymoma 26 | 1,511
subependymal giant cell astrocytoma 26 | 2,287
Obesity 25 | 616
Neurodegenerative disease 24 | 383
dermatomyositis 23 | 966
medulloblastoma 23 | 1,524
sonic hedgehog group medulloblastoma 22 | 1,482
Rheumatoid Arthritis 21 | 1,170
colon cancer 21 | 1,475
group 3 medulloblastoma 21 | 2,254
cutaneous lupus erythematosus 20 | 1,056
Carcinoma 19 | 2,147
Waldenstrons macroglobulinemia 17 | 764
acute quadriplegic myopathy 17 | 1,157
non primary Sjogren syndrome sicca 17 | 840
primary pancreatic ductal adenocarcinoma 17 | 1,271
astrocytoma 16 | 1,493
esophageal adenocarcinoma 16 | 737
gastric carcinoma 16 | 832
juvenile dermatomyositis 16 | 1,189
Atherosclerosis 15 | 275
Atopic dermatitis 15 | 944
Diarrhea 15 | 155
Kidney disease 15 | 397
Multiple Sclerosis 15 | 498
Parkinson's disease 15 | 364
adrenocortical carcinoma 15 | 1,427
posterior fossa group B ependymoma 15 | 1,530
tuberculosis and treatment for 6 months 15 | 686
Coronary artery disease 14 | 240
active Crohn's disease 14 | 918
aldosterone-producing adenoma 14 | 664
Cerebrovascular disease 13 | 231
Down syndrome 13 | 548
Influenza 13 | 142
Mammary Neoplasms 13 | 410
Toxic encephalopathy 13 | 131
primary Sjogren syndrome 13 | 788
Asthma 12 | 349
Endometriosis 12 | 535
Heart disease 12 | 279
Neuropathy 12 | 210
Polycystic Ovary Syndrome 12 | 334
acute myeloid leukemia 12 | 785
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 499
hereditary spastic paraplegia 12 | 313
nasopharyngeal carcinoma 12 | 1,056
progressive supranuclear palsy 12 | 674
Hypertension 11 | 293
Meningitis 11 | 46
atypical teratoid/rhabdoid tumor 11 | 1,095
chronic lymphocytic leukemia 11 | 244
mucosa-associated lymphoid tissue lymphoma 11 | 480
sarcoidosis 11 | 368
Anemia 10 | 252
Autistic Disorder 10 | 320
Diabetes Mellitus, Experimental 10 | 106
Duchenne muscular dystrophy 10 | 602
Pneumonia 10 | 133
Stomach Neoplasms 10 | 282
interstitial lung disease 10 | 292
periodontitis 10 | 269

Tissue

Nervous System 217 | 18,560
Digestive Tract 215 | 18,472
Endocrine System 215 | 18,511
Female tissues 215 | 18,646
Liver and Pancreas 215 | 18,135
Urinary Tract 215 | 18,443
Male tissues 214 | 17,968
Blood and immune system 213 | 17,994
Cardiovascular System 213 | 17,957
Skin and soft tissues 213 | 18,114
Respiratory system 211 | 17,483

Target Family

Non-IDG 126 | 11,969
Enzyme 62 | 4,146
Kinase 14 | 634
Transporter 6 | 473
GPCR 3 | 408
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Ion Channel 1 | 341
Nuclear Receptor 1 | 48

Compartment GO Term

Outer membrane 218 | 218
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Long-chain-fatty-acid--CoA ligase 6 ACSL6 Tbio Enzyme -1.84683 72.3 120
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095
Cytochrome b5 type B CYB5B Tbio Non-IDG -0.89834 7.51 36
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.50018 27956.4 30
LETM1 domain-containing protein 1 LETMD1 Tbio Non-IDG -0.19266 1.43 110
Bcl-2-like protein 11 BCL2L11 Tbio Non-IDG -3.14287 1340.6 903
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.73333 490.7 314
Nesprin-3 SYNE3 Tbio Non-IDG -0.90535 8.74 91
Hexokinase-2 HK2 Tchem Kinase -2.60415 391.1 373
Rab11 family-interacting protein 5 RAB11FIP5 Tbio Non-IDG -1.49558 32.9 56