Development Level

Tbio 140 | 10,625
Tchem 47 | 1,890
Tdark 18 | 7,003
Tclin 13 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased body weight 6 | 174
decreased lean body mass 6 | 195
preweaning lethality, complete... 6 | 633
decreased heart weight 5 | 44
hypoactivity 5 | 89
decreased body length 4 | 108
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
increased mean corpuscular hem... 4 | 93
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
thrombocytopenia 3 | 46
abnormal lens morphology 2 | 73
abnormal sleep behavior 2 | 63
abnormal tibia morphology 2 | 14
decreased circulating LDL chol... 2 | 37
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased mean corpuscular hem... 2 | 34
decreased total retina thickne... 2 | 20
decreased vertical activity 2 | 22
embryonic lethality prior to o... 2 | 148
hyperactivity 2 | 108
immune system phenotype 2 | 17
increased circulating bilirubi... 2 | 16
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased heart weight 2 | 37
short tibia 2 | 82
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cranium morphology 1 | 32
abnormal femur morphology 1 | 14
abnormal joint morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal tail morphology 1 | 17
abnormal vertebrae morphology 1 | 14
absent vibrissae 1 | 14
cataract 1 | 26
convulsive seizures 1 | 11
corneal opacity 1 | 25
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
edema 1 | 11
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hemorrhage 1 | 12
hydrometra 1 | 13
hydrops fetalis 1 | 22
increased body length 1 | 20
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased erythrocyte cell num... 1 | 26
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased red blood cell distr... 1 | 21
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
microphthalmia 1 | 15
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
respiratory system phenotype 1 | 2
shortened PQ interval 1 | 6
small heart 1 | 8
small kidney 1 | 10
small spleen 1 | 11

Disease

ovarian cancer 121 | 8,484
osteosarcoma 100 | 7,933
medulloblastoma, large-cell 91 | 6,234
psoriasis 88 | 6,685
lung cancer 84 | 4,466
glioblastoma 79 | 5,572
atypical teratoid / rhabdoid tumor 64 | 4,369
Cancer 53 | 2,346
malignant mesothelioma 52 | 3,162
invasive ductal carcinoma 49 | 2,950
pilocytic astrocytoma 48 | 3,086
ulcerative colitis 44 | 2,087
non-small cell lung cancer 41 | 2,798
diabetes mellitus 40 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,988
lung adenocarcinoma 40 | 2,713
Breast cancer 39 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,289
pancreatic cancer 39 | 2,300
oligodendroglioma 38 | 2,849
pediatric high grade glioma 37 | 2,712
primitive neuroectodermal tumor 37 | 3,031
lung carcinoma 36 | 2,844
ependymoma 34 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,795
astrocytic glioma 33 | 2,241
ductal carcinoma in situ 32 | 1,745
Pick disease 31 | 1,893
interstitial cystitis 31 | 2,299
tuberculosis 31 | 1,557
adult high grade glioma 30 | 2,148
breast carcinoma 29 | 1,614
cystic fibrosis 29 | 1,665
Alzheimer's disease 28 | 644
Multiple myeloma 28 | 1,327
group 4 medulloblastoma 26 | 1,875
pituitary cancer 26 | 1,972
posterior fossa group A ependymoma 26 | 1,511
subependymal giant cell astrocytoma 26 | 2,287
Obesity 25 | 616
Neurodegenerative disease 24 | 383
dermatomyositis 23 | 933
medulloblastoma 23 | 1,524
sonic hedgehog group medulloblastoma 22 | 1,482
Rheumatoid Arthritis 21 | 1,160
colon cancer 21 | 1,475
group 3 medulloblastoma 21 | 2,254
cutaneous lupus erythematosus 20 | 1,056
Carcinoma 19 | 2,147
Waldenstrons macroglobulinemia 17 | 765
acute quadriplegic myopathy 17 | 1,157
non primary Sjogren syndrome sicca 17 | 840
primary pancreatic ductal adenocarcinoma 17 | 1,271
astrocytoma 16 | 1,493
esophageal adenocarcinoma 16 | 737
gastric carcinoma 16 | 832
juvenile dermatomyositis 16 | 1,189
Atherosclerosis 15 | 275
Atopic dermatitis 15 | 944
Diarrhea 15 | 155
Kidney disease 15 | 396
Multiple Sclerosis 15 | 498
Parkinson's disease 15 | 364
adrenocortical carcinoma 15 | 1,427
posterior fossa group B ependymoma 15 | 1,530
tuberculosis and treatment for 6 months 15 | 686
Coronary artery disease 14 | 240
active Crohn's disease 14 | 918
aldosterone-producing adenoma 14 | 664
Cerebrovascular disease 13 | 231
Down syndrome 13 | 548
Influenza 13 | 142
Mammary Neoplasms 13 | 410
Toxic encephalopathy 13 | 131
primary Sjogren syndrome 13 | 789
Asthma 12 | 349
Endometriosis 12 | 535
Heart disease 12 | 279
Neuropathy 12 | 210
Polycystic Ovary Syndrome 12 | 332
acute myeloid leukemia 12 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 499
hereditary spastic paraplegia 12 | 313
nasopharyngeal carcinoma 12 | 1,056
progressive supranuclear palsy 12 | 674
Chronic Lymphocytic Leukemia 11 | 242
Hypertension 11 | 287
Meningitis 11 | 46
atypical teratoid/rhabdoid tumor 11 | 1,095
mucosa-associated lymphoid tissue lymphoma 11 | 480
sarcoidosis 11 | 358
Anemia 10 | 252
Autistic Disorder 10 | 320
Diabetes Mellitus, Experimental 10 | 106
Duchenne muscular dystrophy 10 | 602
Pneumonia 10 | 133
Stomach Neoplasms 10 | 282
interstitial lung disease 10 | 291
periodontitis 10 | 269

Tissue

Nervous System 217 | 18,561
Digestive Tract 215 | 18,473
Endocrine System 215 | 18,512
Female tissues 215 | 18,647
Liver and Pancreas 215 | 18,136
Urinary Tract 215 | 18,444
Male tissues 214 | 17,969
Blood and immune system 213 | 17,995
Cardiovascular System 213 | 17,958
Skin and soft tissues 213 | 18,115
Respiratory system 211 | 17,484

Target Family

Non-IDG 126 | 11,971
Enzyme 62 | 4,146
Kinase 14 | 634
Transporter 6 | 473
GPCR 3 | 406
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Ion Channel 1 | 341
Nuclear Receptor 1 | 48

Compartment GO Term

Outer membrane 218 | 218
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
Cytochrome b5 CYB5A Tchem Non-IDG -3.24788 1711.2 249
Lipoma-preferred partner LPP Tbio Non-IDG -2.68601 520.6 153
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
Mitofusin-1 MFN1 Tbio Non-IDG -1.99234 91.2 0
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.30451 203.2 252
Alpha-fetoprotein AFP Tbio Non-IDG -4.04711 11505.1 1715