Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
decreased cardiac muscle contr... 1 | 11
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
dilated heart left ventricle 1 | 11
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 5 | 11,493
Cardiomyopathy 5 | 116
Dilated cardiomyopathy 4 | 56
ovarian cancer 4 | 8,520
Arrhythmogenic right ventricular cardiomyopathy 3 | 30
Cardiomyopathy, Dilated 3 | 83
Cardiomyopathy, right ventricular 3 | 7
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Familial isolated dilated cardiomyopathy 2 | 41
LEFT VENTRICULAR NONCOMPACTION 10 2 | 40
LEFT VENTRICULAR NONCOMPACTION 8 2 | 40
LEOPARD syndrome 2 | 20
Middle lobe syndrome 2 | 3
Palpitations 2 | 18
Sudden Cardiac Death 2 | 29
Syncope 2 | 22
Tachycardia, Ventricular 2 | 22
Ventricular arrhythmia 2 | 27
Wooly hair 2 | 17
acute myeloid leukemia 2 | 783
cystic fibrosis 2 | 1,696
group 3 medulloblastoma 2 | 4,104
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
urothelial carcinoma 2 | 318
ANONYCHIA 1 | 20
Acantholysis 1 | 6
Acute coronary syndrome 1 | 39
Afro-textured hair 1 | 13
Alopecia 1 | 115
Aneurysm 1 | 7
Aneurysmal disease 1 | 6
Arrhythmogenic Right Ventricular Dysplasia, Familial, 9 1 | 1
Arrhythmogenic right ventricular cardiomyopathy, type 9 1 | 1
Barrett's esophagus 1 | 182
Brugada syndrome 1 | 29
Cardiac Arrhythmia 1 | 103
Cardiofaciocutaneous syndrome 1 | 15
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Congestive heart failure 1 | 113
Curly hair (finding) 1 | 14
Dizziness 1 | 26
Dyspnea 1 | 76
Dystrophia unguium 1 | 53
Fragile skin 1 | 18
Heart failure 1 | 162
Hyperhidrosis disorder 1 | 81
Hypertrophic Cardiomyopathy 1 | 117
Hypotrichosis 1 | 47
Increased sweating 1 | 81
Keratosis 1 | 37
Kinky hair texture 1 | 13
Liver diseases 1 | 87
Lymphoid leukemia 1 | 160
Mongolian spot 1 | 4
Monilethrix 1 | 18
Myopathy 1 | 185
Nappy hair texture 1 | 13
Nikolsky sign 1 | 6
Oral mucosal blistering 1 | 10
Osteoporosis 1 | 363
Palmoplantar keratosis 1 | 74
Pemphigus 1 | 23
Photosensitive trichothiodystrophy 1 | 30
Premature ventricular contractions 1 | 6
Ritter's disease 1 | 10
Shigellosis 1 | 21
Skin Erosion 1 | 12
Sparse eyebrow 1 | 42
Sparse scalp hair 1 | 42
Sweating 1 | 81
Tooth agenesis 1 | 44
Varicocele 1 | 26
Ventricular aneurysm 1 | 2
Vertigo 1 | 29
Woolly hair, autosomal dominant 1 | 5
Woolly hair, congenital 1 | 5
atypical teratoid/rhabdoid tumor 1 | 357
axial spondyloarthropathy 1 | 28
colon cancer 1 | 1,478
facioscapulohumeral dystrophy 1 | 288
nasopharyngeal carcinoma 1 | 1,058
pediatric high grade glioma 1 | 1,064
pulmonary arterial hypertension 1 | 75
tuberculosis 1 | 2,010

Tissue

Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Male tissues 5 | 17,142
Skin and soft tissues 5 | 17,230
Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Liver and Pancreas 4 | 16,750
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Urinary Tract 4 | 16,678

Target Family

Non-IDG 5 | 12,091

Compartment GO Term

Outer dense plaque of desmosom... 5 | 5
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Keratin, type II cytoskeletal 74 KRT74 Tbio Non-IDG -2.24212 165.9 40
Desmoglein-2 DSG2 Tbio Non-IDG -2.03972 117.7 407
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Junction plakoglobin JUP Tbio Non-IDG -2.01808 101.8 719