Development Level

Tbio 269 | 10,625
Tdark 35 | 7,003
Tchem 34 | 1,890
Tclin 4 | 602

Collection

Ion Channel: IDG Consortium (Targets) 2 | 102
GPCR: IDG Consortium (Targets) 1 | 127
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 17 | 633
embryonic lethality prior to t... 10 | 187
abnormal bone structure 9 | 131
decreased circulating HDL chol... 7 | 77
decreased total body fat amoun... 7 | 186
increased or absent threshold ... 7 | 128
preweaning lethality, incomple... 7 | 260
abnormal bone mineralization 6 | 55
abnormal sleep behavior 6 | 63
decreased grip strength 6 | 123
decreased lean body mass 6 | 195
increased heart weight 6 | 37
abnormal behavior 5 | 226
abnormal lens morphology 5 | 73
decreased body weight 5 | 174
decreased bone mineral content 5 | 157
increased bone mineral content 5 | 92
increased circulating alkaline... 5 | 119
increased grip strength 5 | 83
increased mean corpuscular hem... 5 | 93
increased mean corpuscular vol... 5 | 91
male infertility 5 | 62
abnormal limb bud morphology 4 | 15
decreased circulating LDL chol... 4 | 37
decreased circulating alanine ... 4 | 53
decreased circulating choleste... 4 | 85
decreased circulating insulin ... 4 | 75
increased lean body mass 4 | 107
polydactyly 4 | 22
abnormal QRS complex 3 | 25
abnormal behavioral response t... 3 | 52
abnormal body wall morphology 3 | 7
abnormal facial morphology 3 | 9
abnormal limb morphology 3 | 7
abnormal retinal pigmentation 3 | 61
anophthalmia 3 | 20
cleft palate 3 | 6
decreased CD8-positive, alpha-... 3 | 26
decreased NK T cell number 3 | 28
decreased T cell number 3 | 31
decreased body length 3 | 108
decreased circulating triglyce... 3 | 83
decreased fasted circulating g... 3 | 49
decreased hemoglobin content 3 | 53
decreased lumbar vertebrae num... 3 | 62
decreased prepulse inhibition 3 | 52
embryonic lethality prior to o... 3 | 148
impaired glucose tolerance 3 | 52
increased bone mineral density 3 | 52
increased sacral vertebrae num... 3 | 62
limb grasping 3 | 35
abnormal craniofacial morpholo... 2 | 12
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal retina morphology 2 | 100
abnormal tail movements 2 | 12
cataract 2 | 26
decreased B cell number 2 | 30
decreased NK cell number 2 | 16
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating calcium ... 2 | 33
decreased circulating potassiu... 2 | 17
decreased circulating serum al... 2 | 79
decreased erythrocyte cell num... 2 | 43
decreased gamma-delta T cell n... 2 | 18
decreased heart weight 2 | 44
decreased mean corpuscular hem... 2 | 34
decreased monocyte cell number 2 | 28
decreased respiratory quotient 2 | 12
decreased rib number 2 | 59
decreased startle reflex 2 | 48
decreased vertical activity 2 | 22
edema 2 | 11
enlarged epididymis 2 | 27
enlarged heart 2 | 111
facial cleft 2 | 3
hyperactivity 2 | 108
hypoactivity 2 | 89
immune system phenotype 2 | 17
increased blood urea nitrogen ... 2 | 44
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 26
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 25
increased prepulse inhibition 2 | 21
increased startle reflex 2 | 38
premature death 2 | 5
straub tail 2 | 26
abnormal heart morphology 1 | 51
abnormal neural tube closure 1 | 37
abnormal testis morphology 1 | 30
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
embryonic growth retardation 1 | 28
female infertility 1 | 34
increased CD5-positive Ly6C-po... 1 | 4
increased circulating magnesiu... 1 | 10

Disease

ovarian cancer 208 | 8,491
osteosarcoma 177 | 7,933
psoriasis 150 | 6,685
medulloblastoma, large-cell 142 | 6,234
glioblastoma 130 | 5,572
lung cancer 95 | 4,473
atypical teratoid / rhabdoid tumor 94 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 79 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 78 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 77 | 3,289
pilocytic astrocytoma 71 | 3,086
malignant mesothelioma 69 | 3,163
Breast cancer 66 | 3,098
pancreatic cancer 62 | 2,300
invasive ductal carcinoma 60 | 2,950
ependymoma 58 | 2,514
pediatric high grade glioma 58 | 2,712
lung carcinoma 57 | 2,844
lung adenocarcinoma 56 | 2,714
group 4 medulloblastoma 52 | 1,875
oligodendroglioma 52 | 2,849
subependymal giant cell astrocytoma 52 | 2,287
Pick disease 51 | 1,893
primitive neuroectodermal tumor 50 | 3,031
adult high grade glioma 48 | 2,148
astrocytic glioma 48 | 2,241
non-small cell lung cancer 48 | 2,798
Carcinoma 47 | 2,147
astrocytoma 46 | 1,493
Cancer 45 | 2,346
interstitial cystitis 44 | 2,299
diabetes mellitus 40 | 1,663
ductal carcinoma in situ 40 | 1,745
pituitary cancer 40 | 1,972
cystic fibrosis 39 | 1,670
breast carcinoma 38 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,795
tuberculosis 38 | 1,563
Multiple myeloma 37 | 1,327
ulcerative colitis 37 | 2,087
primary pancreatic ductal adenocarcinoma 34 | 1,271
juvenile dermatomyositis 32 | 1,189
acute quadriplegic myopathy 31 | 1,157
group 3 medulloblastoma 31 | 2,254
Alzheimer's disease 29 | 644
colon cancer 29 | 1,475
dermatomyositis 29 | 966
medulloblastoma 29 | 1,524
Rheumatoid Arthritis 28 | 1,170
atypical teratoid/rhabdoid tumor 27 | 1,095
posterior fossa group A ependymoma 27 | 1,511
Waldenstrons macroglobulinemia 26 | 764
posterior fossa group B ependymoma 26 | 1,530
tuberculosis and treatment for 6 months 26 | 686
Neurodegenerative disease 25 | 383
Duchenne muscular dystrophy 24 | 602
active Crohn's disease 23 | 918
adrenocortical carcinoma 23 | 1,427
spina bifida 23 | 1,064
aldosterone-producing adenoma 20 | 664
hereditary spastic paraplegia 20 | 313
primary Sjogren syndrome 20 | 788
Down syndrome 19 | 548
Intellectual disability 19 | 573
sonic hedgehog group medulloblastoma 19 | 1,482
acute myeloid leukemia 18 | 785
gastric carcinoma 18 | 832
non primary Sjogren syndrome sicca 18 | 840
esophageal adenocarcinoma 17 | 737
progressive supranuclear palsy 17 | 674
Atopic dermatitis 16 | 944
cutaneous lupus erythematosus 16 | 1,056
nasopharyngeal carcinoma 16 | 1,056
pancreatic carcinoma 16 | 567
active ulcerative colitis 15 | 477
Amyotrophic Lateral Sclerosis 13 | 432
IGA Glomerulonephritis 13 | 454
Kidney disease 13 | 397
Multiple Sclerosis 13 | 498
mucosa-associated lymphoid tissue lymphoma 13 | 480
Polycystic Ovary Syndrome 12 | 334
Prostatic Neoplasms 12 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 499
Obesity 11 | 616
sarcoidosis 11 | 368
Congenital disorder of glycosylation 10 | 53
Gaucher disease type 1 10 | 171
Adenoma 9 | 165
Becker muscular dystrophy 9 | 187
Microcephaly 9 | 149
Neuropathy 9 | 210
Parkinson's disease 9 | 364
chronic lymphocytic leukemia 9 | 244
gastric cancer 9 | 436
head and neck cancer and chronic obstructive pulmonary disease 9 | 237
Paraplegia 8 | 71
Schizophrenia 8 | 503
chronic rhinosinusitis 8 | 512
fibroadenoma 8 | 557
hepatocellular carcinoma 8 | 550

Tissue

Nervous System 335 | 18,560
Endocrine System 334 | 18,511
Cardiovascular System 333 | 17,957
Digestive Tract 333 | 18,472
Female tissues 333 | 18,646
Male tissues 333 | 17,968
Urinary Tract 333 | 18,443
Blood and immune system 332 | 17,994
Liver and Pancreas 332 | 18,135
Respiratory system 332 | 17,483
Skin and soft tissues 328 | 18,114

Target Family

Non-IDG 204 | 11,969
Enzyme 116 | 4,146
Transporter 9 | 473
Kinase 6 | 634
GPCR 4 | 408
Ion Channel 3 | 341

Compartment GO Term

Organelle subcompartment 342 | 342
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Trafficking protein particle complex subunit 9 TRAPPC9 Tbio Non-IDG -2.14008 133.3 71
Spexin SPX Tbio Non-IDG -2.76281 568.1 18
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 ASAP2 Tbio Non-IDG -1.14527 15.0 69
Inositol polyphosphate 5-phosphatase K INPP5K Tbio Enzyme -0.84616 8.89 74
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.70375 8561.3 896
Vacuolar protein sorting-associated protein 53 homolog VPS53 Tbio Non-IDG -0.76155 5.77 94
Conserved oligomeric Golgi complex subunit 5 COG5 Tbio Non-IDG -0.92957 8.17 15
ADP-ribosylation factor-like protein 1 ARL1 Tbio Enzyme -0.40932 3.58 187
NSFL1 cofactor p47 NSFL1C Tbio Non-IDG -0.96009 8.42 54
Carboxypeptidase E CPE Tbio Enzyme -2.99888 983.1 216