Development Level

Tbio 126 | 10,625
Tchem 33 | 1,890
Tdark 17 | 7,003
Tclin 9 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased body weight 6 | 174
decreased lean body mass 6 | 195
decreased heart weight 5 | 44
hypoactivity 5 | 89
increased mean corpuscular hem... 5 | 93
preweaning lethality, complete... 5 | 633
decreased body length 4 | 108
decreased bone mineral content 4 | 157
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
decreased total body fat amoun... 4 | 186
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased bone mineral density 3 | 126
decreased grip strength 3 | 123
increased heart weight 3 | 37
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
thrombocytopenia 3 | 46
abnormal lens morphology 2 | 73
abnormal tibia morphology 2 | 14
decreased circulating LDL chol... 2 | 37
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased mean corpuscular hem... 2 | 34
decreased startle reflex 2 | 48
decreased total retina thickne... 2 | 20
decreased vertical activity 2 | 22
hyperactivity 2 | 108
immune system phenotype 2 | 17
increased circulating bilirubi... 2 | 16
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased lean body mass 2 | 107
short tibia 2 | 82
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cranium morphology 1 | 32
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 5
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal tail morphology 1 | 17
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
absent vibrissae 1 | 14
cataract 1 | 26
corneal opacity 1 | 25
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
edema 1 | 11
female infertility 1 | 34
hemorrhage 1 | 12
hydrometra 1 | 13
hydrops fetalis 1 | 22
increased bone mineral content 1 | 92
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
respiratory system phenotype 1 | 2
shortened PQ interval 1 | 6
small heart 1 | 8
small kidney 1 | 10
small spleen 1 | 11

Disease

ovarian cancer 104 | 8,484
osteosarcoma 80 | 7,933
medulloblastoma, large-cell 76 | 6,234
lung cancer 69 | 4,466
psoriasis 67 | 6,685
glioblastoma 63 | 5,572
atypical teratoid / rhabdoid tumor 54 | 4,369
malignant mesothelioma 43 | 3,162
invasive ductal carcinoma 42 | 2,950
Cancer 37 | 2,346
pilocytic astrocytoma 34 | 3,086
non-small cell lung cancer 32 | 2,798
ependymoma 31 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
oligodendroglioma 31 | 2,849
Pick disease 30 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,795
ulcerative colitis 29 | 2,087
astrocytic glioma 28 | 2,241
ductal carcinoma in situ 28 | 1,745
lung adenocarcinoma 28 | 2,713
pediatric high grade glioma 28 | 2,712
Breast cancer 27 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,988
lung carcinoma 27 | 2,844
pancreatic cancer 27 | 2,300
primitive neuroectodermal tumor 27 | 3,031
Multiple myeloma 25 | 1,327
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
adult high grade glioma 24 | 2,148
Alzheimer's disease 23 | 644
group 4 medulloblastoma 23 | 1,875
pituitary cancer 22 | 1,972
Neurodegenerative disease 21 | 383
breast carcinoma 21 | 1,614
diabetes mellitus 21 | 1,663
sonic hedgehog group medulloblastoma 20 | 1,482
colon cancer 19 | 1,475
interstitial cystitis 19 | 2,299
subependymal giant cell astrocytoma 19 | 2,287
tuberculosis 18 | 1,557
Obesity 17 | 616
astrocytoma 17 | 1,493
dermatomyositis 17 | 933
medulloblastoma 17 | 1,524
group 3 medulloblastoma 16 | 2,254
aldosterone-producing adenoma 15 | 664
posterior fossa group A ependymoma 15 | 1,511
posterior fossa group B ependymoma 15 | 1,530
Carcinoma 14 | 2,147
Rheumatoid Arthritis 14 | 1,160
Parkinson's disease 13 | 364
acute quadriplegic myopathy 13 | 1,157
adrenocortical carcinoma 13 | 1,427
tuberculosis and treatment for 6 months 13 | 686
Waldenstrons macroglobulinemia 12 | 765
esophageal adenocarcinoma 12 | 737
juvenile dermatomyositis 12 | 1,189
primary pancreatic ductal adenocarcinoma 12 | 1,271
progressive supranuclear palsy 12 | 674
active Crohn's disease 11 | 918
cystic fibrosis 11 | 1,665
hereditary spastic paraplegia 11 | 313
primary Sjogren syndrome 11 | 789
Atopic dermatitis 10 | 944
Chronic Lymphocytic Leukemia 10 | 242
Toxic encephalopathy 10 | 131
cutaneous lupus erythematosus 10 | 1,056
nasopharyngeal carcinoma 10 | 1,056
non primary Sjogren syndrome sicca 10 | 840
Mammary Neoplasms 9 | 410
Optic atrophy 9 | 43
Polycystic Ovary Syndrome 9 | 332
acute myeloid leukemia 9 | 780
gastric carcinoma 9 | 832
Autistic Disorder 8 | 320
Diabetes Mellitus, Experimental 8 | 106
Multiple Sclerosis 8 | 498
Vascular disease 8 | 281
atypical teratoid/rhabdoid tumor 8 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
spina bifida 8 | 1,064
Endometriosis 7 | 535
chronic rhinosinusitis 7 | 512
gastric cancer 7 | 430
pancreatic carcinoma 7 | 567
Amyotrophic Lateral Sclerosis 6 | 431
COPD 6 | 113
Cardiomyopathy 6 | 110
Down syndrome 6 | 548
Duchenne muscular dystrophy 6 | 602
IGA Glomerulonephritis 6 | 454
Liver carcinoma 6 | 217
Myocardial Ischemia 6 | 169
Nerve Degeneration 6 | 73
Prostatic Neoplasms 6 | 471
active ulcerative colitis 6 | 477
fibroadenoma 6 | 557
mucosa-associated lymphoid tissue lymphoma 6 | 480
tuberculosis and treatment for 3 months 6 | 327

Tissue

Nervous System 184 | 18,561
Blood and immune system 183 | 17,995
Digestive Tract 183 | 18,473
Female tissues 183 | 18,647
Liver and Pancreas 183 | 18,136
Urinary Tract 183 | 18,444
Cardiovascular System 182 | 17,958
Endocrine System 182 | 18,512
Male tissues 182 | 17,969
Respiratory system 181 | 17,484
Skin and soft tissues 181 | 18,115

Target Family

Non-IDG 108 | 11,971
Enzyme 51 | 4,146
Kinase 14 | 634
Transporter 5 | 473
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 406
Ion Channel 1 | 341
Nuclear Receptor 1 | 48

Compartment GO Term

Organelle outer membrane 185 | 185
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
Cytochrome b5 CYB5A Tchem Non-IDG -3.24788 1711.2 249
Mitofusin-1 MFN1 Tbio Non-IDG -1.99234 91.2 0
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.30451 203.2 252
ATP synthase F(0) complex subunit C2, mitochondrial ATP5G2 Tbio Enzyme -1.03087 9.31 110
Protein Tob1 TOB1 Tbio Non-IDG -1.56387 42.5 170
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.80784 708.8 168
Cytochrome c CYCS Tbio Non-IDG -3.73952 4771.4 630
NADH-cytochrome b5 reductase 3 CYB5R3 Tchem Enzyme -1.93440 89.2 241