Development Level

Tbio 741 | 11,445
Tdark 195 | 6,588
Tchem 118 | 1,598
Tclin 88 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 98 | 979
preweaning lethality, incomple... 32 | 499
embryonic lethality prior to o... 26 | 239
embryonic lethality prior to t... 26 | 278
abnormal behavior 23 | 298
abnormal embryo size 16 | 220
decreased total body fat amoun... 16 | 207
decreased vertical activity 16 | 208
increased lean body mass 16 | 172
increased total body fat amoun... 16 | 134
decreased body weight 15 | 161
enlarged heart 14 | 210
hyperactivity 14 | 148
decreased bone mineral content 13 | 151
decreased lean body mass 13 | 135
abnormal bone structure 12 | 187
hypoactivity 11 | 132
abnormal heart morphology 10 | 162
cataract 10 | 92
embryonic growth retardation 10 | 106
abnormal lens morphology 9 | 81
increased mean corpuscular hem... 9 | 96
increased startle reflex 9 | 112
abnormal sleep behavior 7 | 70
decreased circulating HDL chol... 7 | 68
decreased circulating glucose ... 7 | 126
decreased hematocrit 7 | 46
decreased mean corpuscular vol... 7 | 79
increased circulating alkaline... 7 | 122
male infertility 7 | 123
prenatal lethality prior to he... 7 | 87
abnormal gait 6 | 69
abnormal snout morphology 6 | 23
decreased body length 6 | 101
decreased circulating LDL chol... 6 | 38
decreased circulating alkaline... 6 | 46
decreased circulating choleste... 6 | 93
decreased grip strength 6 | 116
decreased hemoglobin content 6 | 68
increased circulating sodium l... 6 | 71
increased fasted circulating g... 6 | 76
pallor 6 | 34
thrombocytopenia 6 | 56
abnormal neural tube closure 5 | 46
abnormal skin morphology 5 | 50
decreased bone mineral density 5 | 126
decreased circulating serum al... 5 | 82
decreased heart weight 5 | 27
decreased lymphocyte cell numb... 5 | 83
edema 5 | 59
improved glucose tolerance 5 | 79
increased bone mineral content 5 | 108
increased circulating HDL chol... 5 | 80
increased circulating choleste... 5 | 66
increased circulating phosphat... 5 | 26
increased heart weight 5 | 62
increased mean corpuscular vol... 5 | 92
increased monocyte cell number 5 | 63
increased red blood cell distr... 5 | 34
short tibia 5 | 97
abnormal coat-hair pigmentatio... 4 | 64
abnormal placenta size 4 | 20
abnormal seminal vesicle morph... 4 | 114
decreased circulating aspartat... 4 | 34
decreased circulating insulin ... 4 | 76
decreased circulating phosphat... 4 | 27
decreased circulating total pr... 4 | 49
decreased circulating triglyce... 4 | 79
decreased erythrocyte cell num... 4 | 62
decreased leukocyte cell numbe... 4 | 73
decreased mean corpuscular hem... 4 | 50
decreased total retina thickne... 4 | 17
female infertility 4 | 60
impaired glucose tolerance 4 | 75
increased circulating calcium ... 4 | 34
increased prepulse inhibition 4 | 32
small superior vagus ganglion 4 | 74
small testis 4 | 58
small thymus 4 | 16
tremors 4 | 39
abnormal bone mineralization 3 | 38
abnormal cranium morphology 3 | 36
decreased caudal vertebrae num... 3 | 53
decreased circulating alanine ... 3 | 47
decreased circulating calcium ... 3 | 36
decreased circulating creatini... 3 | 39
decreased circulating iron lev... 3 | 32
decreased fasted circulating g... 3 | 65
decreased lactate dehydrogenas... 3 | 16
decreased prepulse inhibition 3 | 82
decreased red blood cell distr... 3 | 41
decreased startle reflex 3 | 75
increased anti-nuclear antigen... 3 | 19
increased bone mineral density 3 | 72
increased circulating bilirubi... 3 | 16
increased circulating chloride... 3 | 41
increased or absent threshold ... 3 | 101
pale yolk sac 3 | 25
persistence of hyaloid vascula... 3 | 33
prolonged QT interval 3 | 38

Disease

ovarian cancer 625 | 8,520
Carcinoma 584 | 11,493
osteosarcoma 520 | 7,950
medulloblastoma, large-cell 393 | 6,241
psoriasis 376 | 6,694
lung cancer 371 | 4,740
glioblastoma 346 | 5,792
atypical teratoid / rhabdoid tumor 305 | 5,112
ependymoma 265 | 4,679
group 3 medulloblastoma 238 | 4,104
Breast cancer 225 | 3,578
adult high grade glioma 217 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 211 | 1,962
intraductal papillary-mucinous neoplasm (IPMN) 209 | 3,291
malignant mesothelioma 205 | 3,232
Cancer 193 | 2,499
Multiple myeloma 188 | 1,332
invasive ductal carcinoma 184 | 2,951
non-small cell lung cancer 176 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 175 | 2,989
astrocytic glioma 166 | 2,597
oligodendroglioma 163 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 159 | 2,955
primitive neuroectodermal tumor 157 | 3,035
lung adenocarcinoma 152 | 2,716
Astrocytoma, Pilocytic 145 | 3,081
Autosomal recessive predisposition 142 | 1,442
pancreatic cancer 130 | 2,398
tuberculosis 129 | 2,010
lung carcinoma 127 | 2,843
Pick disease 125 | 1,894
diabetes mellitus 125 | 1,728
group 4 medulloblastoma 119 | 1,855
subependymal giant cell astrocytoma 115 | 2,287
breast carcinoma 114 | 1,638
ulcerative colitis 108 | 1,819
Schizophrenia 100 | 1,160
ductal carcinoma in situ 99 | 1,745
colon cancer 95 | 1,478
Kidney cancer 93 | 2,613
Rheumatoid arthritis 91 | 1,191
Epilepsy 90 | 792
interstitial cystitis 90 | 2,312
Waldenstrons macroglobulinemia 88 | 765
acute quadriplegic myopathy 87 | 1,158
non primary Sjogren syndrome sicca 86 | 891
pituitary cancer 86 | 1,972
Alzheimer's disease 85 | 658
dermatomyositis 85 | 966
adrenocortical carcinoma 84 | 1,428
cystic fibrosis 82 | 1,696
astrocytoma 79 | 1,146
Cognitive delay 78 | 608
Global developmental delay 78 | 608
Mental and motor retardation 78 | 608
Neurodegenerative disease 77 | 414
Seizures 77 | 596
acute myeloid leukemia 77 | 783
Obesity 75 | 678
Intellectual disability 73 | 1,016
juvenile dermatomyositis 73 | 1,187
Muscle hypotonia 71 | 571
nasopharyngeal carcinoma 69 | 1,058
pediatric high grade glioma 65 | 1,064
Cerebellar Ataxia 64 | 304
Liver Cirrhosis, Experimental 63 | 769
Parkinson's disease 63 | 392
aldosterone-producing adenoma 61 | 665
primary pancreatic ductal adenocarcinoma 61 | 1,109
Bipolar Disorder 59 | 666
Mammary Neoplasms 59 | 425
Breast Neoplasms 58 | 445
Failure to gain weight 58 | 365
Pediatric failure to thrive 58 | 365
Dull intelligence 55 | 645
Leigh disease 55 | 100
Low intelligence 55 | 645
Mental Retardation 55 | 645
Mental deficiency 55 | 645
Optic Atrophy 55 | 242
Poor school performance 55 | 645
Dystonia 53 | 164
Toxic encephalopathy 53 | 141
cutaneous lupus erythematosus 53 | 1,057
Diabetes mellitus type 2 52 | 69
Treatment Refractory Type 2 Diabetes Mellitus 51 | 53
Amyotrophic lateral sclerosis 50 | 451
Depressive disorder 50 | 409
Hyperreflexia 49 | 209
Vascular disease 49 | 319
Blepharoptosis 48 | 231
Nystagmus 48 | 317
Acidosis, Lactic 47 | 97
Lactic acidemia 47 | 95
Prostatic Neoplasms 46 | 495
Atopic dermatitis 45 | 952
hereditary spastic paraplegia 45 | 318
Neuropathy 44 | 261
Stomach Neoplasms 44 | 300
primary Sjogren syndrome 43 | 735

Tissue

Endocrine System 1,118 | 18,159
Digestive Tract 1,108 | 17,369
Female tissues 1,103 | 17,400
Male tissues 1,101 | 17,142
Liver and Pancreas 1,100 | 16,750
Skin and soft tissues 1,099 | 17,230
Blood and immune system 1,095 | 16,909
Urinary Tract 1,092 | 16,678
Nervous System 1,091 | 16,725
Respiratory system 1,082 | 16,393
Cardiovascular System 1,062 | 15,192

Target Family

Non-IDG 587 | 12,091
Enzyme 370 | 4,145
Transporter 71 | 473
Kinase 40 | 634
Transcription Factor 32 | 1,400
Ion Channel 17 | 344
Epigenetic 12 | 242
GPCR 9 | 408
Nuclear Receptor 3 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

Organelle envelope 1,142 | 1,142
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -2.00007 98.7 330
Uncharacterized protein C2orf42 C2orf42 Tdark Non-IDG 0.95 0.09 69
NTF2-related export protein 1 NXT1 Tbio Non-IDG -1.49831 29.4 91
DnaJ homolog subfamily C member 15 DNAJC15 Tbio Non-IDG -1.67016 50.2 31
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
MICOS complex subunit MIC13 C19orf70 Tbio Non-IDG -1.22343 17.5 18
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Solute carrier family 25 member 47 SLC25A47 Tbio Transporter 0.03 0.48 83
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39