Development Level
Tbio | 8,397 | 11,445 | |
Tdark | 2,282 | 6,588 | |
Tchem | 1,164 | 1,598 | |
Tclin | 395 | 613 |
Collection
RFA-RM-18-021 | 132 | 328 | |
Kinase: IDG Consortium (Target... | 87 | 125 | |
Kinase: IDG Consortium (Comple... | 32 | 37 | |
Ion Channel: IDG Consortium (T... | 27 | 99 | |
GPCR: IDG Consortium (Targets) | 22 | 126 | |
GPCR: IDG Consortium (Complete... | 8 | 25 |
IMPC Phenotype
preweaning lethality, complete... | 863 | 979 | |
preweaning lethality, incomple... | 371 | 499 | |
embryonic lethality prior to t... | 253 | 278 | |
embryonic lethality prior to o... | 217 | 239 | |
abnormal behavior | 209 | 298 | |
abnormal embryo size | 186 | 220 | |
decreased total body fat amoun... | 154 | 207 | |
abnormal bone structure | 139 | 187 | |
decreased vertical activity | 135 | 208 | |
enlarged heart | 133 | 210 | |
decreased body weight | 131 | 161 | |
increased lean body mass | 121 | 172 | |
decreased bone mineral content | 113 | 151 | |
hypoactivity | 109 | 132 | |
decreased lean body mass | 108 | 135 | |
abnormal heart morphology | 106 | 162 | |
increased total body fat amoun... | 106 | 134 | |
hyperactivity | 99 | 148 | |
embryonic growth retardation | 96 | 106 | |
decreased bone mineral density | 93 | 126 | |
decreased circulating glucose ... | 93 | 126 | |
decreased grip strength | 93 | 116 | |
increased circulating alkaline... | 91 | 122 | |
increased startle reflex | 91 | 112 | |
male infertility | 91 | 123 | |
abnormal seminal vesicle morph... | 81 | 114 | |
decreased circulating choleste... | 79 | 93 | |
increased bone mineral content | 75 | 108 | |
decreased body length | 73 | 101 | |
prenatal lethality prior to he... | 72 | 87 | |
increased mean corpuscular vol... | 71 | 92 | |
cataract | 70 | 92 | |
short tibia | 69 | 97 | |
increased or absent threshold ... | 68 | 101 | |
increased mean corpuscular hem... | 67 | 96 | |
decreased circulating serum al... | 65 | 82 | |
decreased mean corpuscular vol... | 64 | 79 | |
decreased lymphocyte cell numb... | 62 | 83 | |
abnormal lens morphology | 61 | 81 | |
decreased prepulse inhibition | 61 | 82 | |
increased fasted circulating g... | 60 | 76 | |
impaired glucose tolerance | 59 | 75 | |
decreased circulating HDL chol... | 58 | 68 | |
decreased circulating triglyce... | 58 | 79 | |
decreased hemoglobin content | 57 | 68 | |
decreased leukocyte cell numbe... | 55 | 73 | |
improved glucose tolerance | 55 | 79 | |
increased bone mineral density | 55 | 72 | |
increased circulating HDL chol... | 54 | 80 | |
edema | 52 | 59 | |
increased circulating sodium l... | 52 | 71 | |
small superior vagus ganglion | 52 | 74 | |
abnormal gait | 51 | 69 | |
abnormal retina morphology | 51 | 71 | |
decreased circulating insulin ... | 51 | 76 | |
decreased startle reflex | 51 | 75 | |
increased heart weight | 51 | 62 | |
abnormal kidney morphology | 50 | 65 | |
abnormal behavioral response t... | 49 | 66 | |
abnormal coat-hair pigmentatio... | 48 | 64 | |
increased circulating choleste... | 48 | 66 | |
decreased fasted circulating g... | 47 | 65 | |
decreased erythrocyte cell num... | 46 | 62 | |
abnormal eye morphology | 45 | 68 | |
increased monocyte cell number | 45 | 63 | |
abnormal sleep behavior | 44 | 70 | |
female infertility | 43 | 60 | |
decreased mean corpuscular hem... | 42 | 50 | |
thrombocytopenia | 42 | 56 | |
abnormal neural tube closure | 41 | 46 | |
decreased circulating total pr... | 41 | 49 | |
small testis | 41 | 58 | |
decreased caudal vertebrae num... | 40 | 53 | |
decreased circulating alanine ... | 39 | 47 | |
decreased circulating alkaline... | 39 | 46 | |
abnormal spleen morphology | 38 | 55 | |
decreased blood urea nitrogen ... | 37 | 51 | |
increased circulating chloride... | 36 | 41 | |
decreased hematocrit | 35 | 46 | |
increased blood urea nitrogen ... | 35 | 48 | |
decreased circulating LDL chol... | 34 | 38 | |
hydrometra | 34 | 53 | |
increased hemoglobin content | 34 | 45 | |
increased leukocyte cell numbe... | 34 | 47 | |
increased neutrophil cell numb... | 34 | 46 | |
abnormal skin morphology | 33 | 50 | |
tremors | 33 | 39 | |
abnormal testis morphology | 32 | 43 | |
increased circulating triglyce... | 32 | 42 | |
increased mean platelet volume | 31 | 45 | |
decreased circulating creatini... | 30 | 39 | |
enlarged spleen | 30 | 41 | |
increased circulating creatini... | 30 | 38 | |
increased grip strength | 30 | 41 | |
increased hematocrit | 30 | 46 | |
decreased circulating calcium ... | 29 | 36 | |
abnormal bone mineralization | 28 | 38 | |
abnormal cornea morphology | 28 | 31 | |
abnormal craniofacial morpholo... | 28 | 33 | |
pallor | 28 | 34 |
Disease
Tissue
Endocrine System | 11,827 | 18,159 | |
Digestive Tract | 11,557 | 17,369 | |
Female tissues | 11,533 | 17,400 | |
Skin and soft tissues | 11,521 | 17,230 | |
Male tissues | 11,426 | 17,142 | |
Blood and immune system | 11,334 | 16,909 | |
Liver and Pancreas | 11,294 | 16,750 | |
Nervous System | 11,275 | 16,725 | |
Urinary Tract | 11,266 | 16,678 | |
Respiratory system | 11,112 | 16,393 | |
Cardiovascular System | 10,572 | 15,192 |
Target Family
Non-IDG | 6,585 | 12,091 | |
Enzyme | 2,978 | 4,145 | |
Transcription Factor | 1,382 | 1,400 | |
Kinase | 465 | 634 | |
Transporter | 253 | 473 | |
Epigenetic | 223 | 242 | |
GPCR | 132 | 408 | |
Ion Channel | 131 | 344 | |
Nuclear Receptor | 47 | 48 | |
TF/Epigenetic | 37 | 38 | |
oGPCR | 5 | 421 |
Compartment GO Term
Organelle | 12,238 | 12,238 | |
cellular_component | 18,320 | 18,320 | |
Cell | 16,178 | 16,178 | |
Cell part | 16,177 | 16,177 | |
Intracellular | 14,109 | 14,109 | |
Intracellular part | 13,972 | 13,972 | |
Intracellular organelle | 12,025 | 12,025 | |
membrane-bounded organelle | 11,132 | 11,132 | |
Cytoplasm | 10,983 | 10,983 | |
Intracellular membrane-bounded... | 10,341 | 10,341 | |
Cytoplasmic part | 9,247 | 9,247 | |
Organelle part | 8,975 | 8,975 | |
Intracellular organelle part | 8,783 | 8,783 | |
Membrane | 8,531 | 8,531 | |
Nucleus | 7,562 | 7,562 | |
Cytosol | 6,686 | 6,686 | |
Membrane part | 6,554 | 6,554 | |
Plasma membrane | 5,830 | 5,830 | |
Macromolecular complex | 5,475 | 5,475 | |
Intrinsic component of membran... | 5,458 | 5,458 | |
Cell periphery | 5,382 | 5,382 | |
Integral component of membrane | 5,331 | 5,331 | |
Intracellular organelle lumen | 5,090 | 5,090 | |
Organelle lumen | 5,090 | 5,090 | |
membrane-enclosed lumen | 5,090 | 5,090 | |
Nucleoplasm | 5,077 | 5,077 | |
Nuclear part | 4,290 | 4,290 | |
Endomembrane system | 4,237 | 4,237 | |
Intracellular non-membrane-bou... | 3,975 | 3,975 | |
non-membrane-bounded organelle | 3,974 | 3,974 | |
Nuclear lumen | 3,968 | 3,968 | |
Protein complex | 3,674 | 3,674 | |
Organelle membrane | 2,846 | 2,846 | |
Extracellular region | 2,732 | 2,732 | |
Plasma membrane part | 2,594 | 2,594 | |
Vesicle | 2,342 | 2,342 | |
Cytoplasmic vesicle | 2,218 | 2,218 | |
Intracellular vesicle | 2,217 | 2,217 | |
Cytoskeleton | 2,108 | 2,108 | |
Endoplasmic reticulum | 2,001 | 2,001 | |
Bounding membrane of organelle | 1,956 | 1,956 | |
Golgi apparatus | 1,933 | 1,933 | |
Intrinsic component of plasma ... | 1,749 | 1,749 | |
Integral component of plasma m... | 1,693 | 1,693 | |
Catalytic complex | 1,642 | 1,642 | |
Cytoskeletal part | 1,637 | 1,637 | |
Extracellular region part | 1,628 | 1,628 | |
Vesicles | 1,613 | 1,613 | |
Mitochondrion | 1,576 | 1,576 | |
Whole membrane | 1,548 | 1,548 | |
Cell projection | 1,541 | 1,541 | |
Cytoplasmic vesicle part | 1,513 | 1,513 | |
Endoplasmic reticulum part | 1,359 | 1,359 | |
GO:0031975 | 1,150 | 1,150 | |
Organelle envelope | 1,142 | 1,142 | |
Microtubule cytoskeleton | 1,137 | 1,137 | |
Extracellular space | 1,124 | 1,124 | |
Nucleoplasm part | 1,122 | 1,122 | |
Nuclear outer membrane-endopla... | 1,121 | 1,121 | |
Endoplasmic reticulum membrane | 1,103 | 1,103 | |
Chromosome | 1,039 | 1,039 | |
Mitochondrial part | 1,036 | 1,036 | |
Mitochondria | 998 | 998 | |
Secretory vesicle | 971 | 971 | |
Neuron part | 970 | 970 | |
Supramolecular polymer | 967 | 967 | |
Supramolecular complex | 966 | 966 | |
Cell junction | 960 | 960 | |
Supramolecular fiber | 959 | 959 | |
Golgi apparatus part | 951 | 951 | |
Nucleoli | 942 | 942 | |
Endosome | 930 | 930 | |
Nucleolus | 926 | 926 | |
Chromosomal part | 889 | 889 | |
GO:0098796 | 884 | 884 | |
Ribonucleoprotein complex | 865 | 865 | |
Secretory granule | 852 | 852 | |
Cell projection part | 850 | 850 | |
Intracellular ribonucleoprotei... | 850 | 850 | |
Transferase complex | 849 | 849 | |
Cell surface | 842 | 842 | |
Plasma membrane region | 841 | 841 | |
Vesicle membrane | 801 | 801 | |
Cytoplasmic vesicle membrane | 795 | 795 | |
Polymeric cytoskeletal fiber | 764 | 764 | |
Mitochondrial envelope | 746 | 746 | |
Vacuole | 732 | 732 | |
Nuclear body | 725 | 725 | |
Golgi membrane | 724 | 724 | |
Microtubule organizing center | 721 | 721 | |
Extracellular matrix | 714 | 714 | |
Neuron projection | 712 | 712 | |
Centrosome | 696 | 696 | |
Mitochondrial membrane | 696 | 696 | |
Receptor complex | 686 | 686 | |
Synapse | 663 | 663 | |
Lysosome | 624 | 624 | |
Lytic vacuole | 624 | 624 | |
Chromatin | 565 | 565 | |
Endosomal part | 565 | 565 |
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