Development Level

Tdark 55 | 6,569
Tbio 48 | 11,178
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
abnormal bone structure 2 | 187
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
decreased circulating glucose ... 1 | 126
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 63 | 8,297
osteosarcoma 35 | 7,766
lung cancer 31 | 4,607
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,911
Carcinoma 23 | 11,192
Multiple myeloma 19 | 1,296
psoriasis 18 | 6,514
non primary Sjogren syndrome sicca 15 | 861
Breast cancer 13 | 3,469
medulloblastoma, large-cell 13 | 6,086
glioblastoma 11 | 5,635
group 3 medulloblastoma 11 | 4,002
non-small cell lung cancer 11 | 2,799
acute myeloid leukemia 9 | 760
atypical teratoid / rhabdoid tumor 9 | 4,971
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,204
diabetes mellitus 8 | 1,683
malignant mesothelioma 8 | 3,135
Breast Neoplasms 7 | 423
Mammary Neoplasms 7 | 403
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,902
astrocytic glioma 6 | 2,530
lung adenocarcinoma 6 | 2,627
colon cancer 5 | 1,428
ependymoma 5 | 4,559
invasive ductal carcinoma 5 | 2,867
pediatric high grade glioma 5 | 1,035
Brain glioma 4 | 7
Disease Progression 4 | 133
Stomach Neoplasms 4 | 287
Waldenstrons macroglobulinemia 4 | 742
adult high grade glioma 4 | 3,701
breast carcinoma 4 | 1,589
group 4 medulloblastoma 4 | 1,806
Combined oxidative phosphorylation deficiency 3 | 14
Diamond-Blackfan anemia 3 | 31
Leigh disease 3 | 100
Ophthalmoplegia 3 | 105
Optic Atrophy 3 | 239
Pick disease 3 | 1,856
Retinitis pigmentosa 4 3 | 38
active Crohn's disease 3 | 882
cystic fibrosis 3 | 1,629
dermatomyositis 3 | 941
lung carcinoma 3 | 2,755
nasopharyngeal carcinoma 3 | 1,024
subependymal giant cell astrocytoma 3 | 2,230
tuberculosis and treatment for 6 months 3 | 399
Acidosis, Lactic 2 | 97
Acquired metabolic disease 2 | 329
Adenocarcinoma of lung 2 | 140
Autosomal recessive predisposition 2 | 1,407
Cancer 2 | 2,388
Disease Models, Animal 2 | 148
Elevated hepatic transaminases 2 | 79
Hepatic enzyme increased 2 | 79
Increased serum lactate 2 | 60
Kidney cancer 2 | 2,548
Lactic acidemia 2 | 95
Leber hereditary optic neuropathy 2 | 14
Liver Dysfunction 2 | 97
Liver enzymes abnormal 2 | 79
Liver function test increased 2 | 79
Liver function tests abnormal finding 2 | 79
MELAS syndrome 2 | 18
Melanoma 2 | 689
Obesity 2 | 655
Osteoporosis 2 | 348
Pseudoxanthoma elasticum 2 | 17
Subclinical abnormal liver function tests 2 | 79
Transaminases increased 2 | 79
hepatocellular carcinoma 2 | 536
hereditary spastic paraplegia 2 | 313
primitive neuroectodermal tumor 2 | 2,957
sonic hedgehog group medulloblastoma 2 | 459
ulcerative colitis 2 | 1,765
Abnormal vision 1 | 51
Age related macular degeneration 1 | 71
Amyotrophic lateral sclerosis type 5 1 | 13
Blindness, Cortical 1 | 24
Cervical cancer 1 | 24
Dyslexia 1 | 42
Edema 1 | 80
Episodic vomiting 1 | 10
Frequent vomiting 1 | 10
Gastroenteritis 1 | 40
Gastroparesis 1 | 22
Hemianopsia 1 | 15
Hemiparesis 1 | 32
Hereditary spherocytosis type 1 1 | 23
Hypotrichosis of the scalp 1 | 6
Neuronal ceroid lipofuscinosis 1 1 | 15
Pneumocystosis 1 | 17
Polyneuropathy 1 | 63
Sparse body hair 1 | 31
Sparse eyebrow 1 | 40
Sparse eyelashes 1 | 29
Specific language impairment 1 | 33
Static Tremor 1 | 21

Tissue

Blood and immune system 102 | 16,909
Cardiovascular System 102 | 15,192
Digestive Tract 102 | 17,369
Endocrine System 102 | 18,159
Female tissues 102 | 17,400
Liver and Pancreas 102 | 16,750
Male tissues 102 | 17,142
Nervous System 102 | 16,725
Respiratory system 102 | 16,393
Skin and soft tissues 102 | 17,230
Urinary Tract 102 | 16,678

Target Family

Non-IDG 93 | 12,091
Enzyme 11 | 4,145

Compartment GO Term

Organellar ribosome 104 | 104
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
39S ribosomal protein L27, mitochondrial MRPL27 Tdark Non-IDG 0.60 0.05 48
39S ribosomal protein L36, mitochondrial MRPL36 Tdark Non-IDG -1.19524 14.7 33
28S ribosomal protein S22, mitochondrial MRPS22 Tbio Non-IDG -2.42971 211.9 107
28S ribosomal protein S35, mitochondrial MRPS35 Tdark Non-IDG 0.00000 84
39S ribosomal protein L48, mitochondrial MRPL48 Tdark Non-IDG -0.13072 1.06 149
28S ribosomal protein S10, mitochondrial MRPS10 Tdark Non-IDG -0.42752 2.60 107
39S ribosomal protein L2, mitochondrial MRPL2 Tdark Non-IDG 0.30 0.34 104
28S ribosomal protein S21, mitochondrial MRPS21 Tdark Non-IDG 0.60 0.25 0
60S ribosomal protein L12 RPL12 Tbio Non-IDG -1.85470 69.6 143
28S ribosomal protein S6, mitochondrial MRPS6 Tdark Non-IDG 0.02 1.21 37