Development Level

Tbio 17 | 11,445
Tchem 3 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal neural tube closure 1 | 46
decreased circulating glycerol... 1 | 16
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499
small adrenal glands 1 | 16
small spleen 1 | 19

Disease

ovarian cancer 16 | 8,520
osteosarcoma 14 | 7,950
Carcinoma 11 | 11,493
glioblastoma 11 | 5,792
atypical teratoid / rhabdoid tumor 10 | 5,112
medulloblastoma, large-cell 9 | 6,241
ependymoma 8 | 4,679
Multiple myeloma 6 | 1,332
adult high grade glioma 6 | 3,801
lung cancer 6 | 4,740
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
psoriasis 4 | 6,694
subependymal giant cell astrocytoma 4 | 2,287
Cognitive delay 3 | 608
Congenital disorder of glycosylation 3 | 54
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Osteoporosis 3 | 363
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
active Crohn's disease 3 | 922
juvenile dermatomyositis 3 | 1,187
pituitary cancer 3 | 1,972
Arthritis 2 | 290
Asthma 2 | 385
Attention deficit hyperactivity disorder 2 | 278
Biliary cirrhosis 2 | 45
Cancer 2 | 2,499
Cholestasis 2 | 155
Dull intelligence 2 | 645
Failure to gain weight 2 | 365
Hereditary spherocytosis type 3 2 | 14
Hypercalcemia 2 | 59
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Liver Cirrhosis, Biliary 2 | 33
Liver disease 2 | 237
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Osteonecrosis 2 | 27
Osteopetrosis 2 | 43
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
malignant mesothelioma 2 | 3,232
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
Ankylosing spondylitis 1 | 140
Bone pain 1 | 42
Botulism 1 | 24
Compression of optic nerve 1 | 7
Conductive hearing loss 1 | 123
Craniofacial Abnormalities 1 | 151
Gout 1 | 106
Hyperparathyroidism 1 | 48
Hyperphosphatemia 1 | 32
Hypophosphatemia 1 | 40
Isoelectric focusing of serum transferrin consistent with CDG type I 1 | 10
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Lymphopenia 1 | 67
Mammary Neoplasms, Experimental 1 | 154
Metabolic syndrome X 1 | 52
Osteomalacia 1 | 35
Placental insufficiency 1 | 18
Pre-Eclampsia 1 | 68
Rickets 1 | 49
Thyrotoxicosis 1 | 38
permanent atrial fibrillation 1 | 45

Tissue

Blood and immune system 22 | 16,909
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Digestive Tract 21 | 17,369
Liver and Pancreas 21 | 16,750
Respiratory system 21 | 16,393
Cardiovascular System 20 | 15,192

Target Family

Enzyme 12 | 4,145
Non-IDG 8 | 12,091
Transporter 2 | 473

Compartment GO Term

Oligosaccharyltransferase comp... 22 | 22
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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