Development Level

Tbio 102 | 11,178
Tdark 12 | 6,569
Tchem 8 | 1,885

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal behavior 4 | 298
abnormal retina morphology 4 | 71
decreased total body fat amoun... 4 | 207
decreased grip strength 3 | 116
improved glucose tolerance 3 | 79
increased or absent threshold ... 3 | 101
abnormal heart left ventricle ... 2 | 16
abnormal retinal vasculature m... 2 | 27
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating insulin ... 2 | 76
decreased startle reflex 2 | 75
enlarged heart 2 | 210
hyperactivity 2 | 148
hypoactivity 2 | 132
increased body weight 2 | 25
increased bone mineral content 2 | 108
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
cyanosis 1 | 7
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased vertical activity 1 | 24
male infertility 1 | 123
mammalian phenotype 1 | 17
shortened PR interval 1 | 6
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 87 | 11,192
ovarian cancer 76 | 8,297
osteosarcoma 58 | 7,766
psoriasis 55 | 6,514
medulloblastoma, large-cell 53 | 6,086
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,204
atypical teratoid / rhabdoid tumor 45 | 4,971
ependymoma 43 | 4,559
glioblastoma 42 | 5,635
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,872
invasive ductal carcinoma 41 | 2,867
non-small cell lung cancer 41 | 2,799
interstitial cystitis 38 | 2,237
Breast cancer 37 | 3,469
lung cancer 37 | 4,607
lung adenocarcinoma 35 | 2,627
group 3 medulloblastoma 34 | 4,002
ductal carcinoma in situ 32 | 1,686
pancreatic cancer 31 | 2,322
lung carcinoma 29 | 2,755
Cancer 28 | 2,388
adult high grade glioma 27 | 3,701
Kidney cancer 26 | 2,548
primitive neuroectodermal tumor 26 | 2,957
malignant mesothelioma 25 | 3,135
Astrocytoma, Pilocytic 24 | 3,006
oligodendroglioma 24 | 2,768
spina bifida 24 | 1,053
subependymal giant cell astrocytoma 23 | 2,230
astrocytic glioma 21 | 2,530
breast carcinoma 21 | 1,589
pituitary cancer 21 | 1,915
cystic fibrosis 17 | 1,629
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,911
ulcerative colitis 17 | 1,765
Pick disease 14 | 1,856
active Crohn's disease 14 | 882
group 4 medulloblastoma 14 | 1,806
primary pancreatic ductal adenocarcinoma 14 | 1,071
Schizophrenia 13 | 1,136
nasopharyngeal carcinoma 13 | 1,024
Prostatic Neoplasms 12 | 472
esophageal adenocarcinoma 12 | 696
Autosomal recessive predisposition 11 | 1,407
Intellectual disability 11 | 998
active ulcerative colitis 11 | 736
adrenocortical carcinoma 11 | 1,385
gastric carcinoma 11 | 781
tuberculosis 11 | 1,963
Atopic dermatitis 10 | 915
diabetes mellitus 10 | 1,683
colon cancer 9 | 1,428
juvenile dermatomyositis 9 | 1,147
Inflammatory bowel disease 8 | 148
Melanoma 8 | 689
Skin cancer 8 | 451
acute quadriplegic myopathy 8 | 1,133
astrocytoma 8 | 1,113
cutaneous lupus erythematosus 8 | 1,016
pediatric high grade glioma 8 | 1,035
urothelial carcinoma 8 | 303
Breast Neoplasms 7 | 423
Down syndrome 7 | 480
Dull intelligence 7 | 634
Kidney disease 7 | 411
Liver Cirrhosis, Experimental 7 | 733
Liver cancer 7 | 589
Low intelligence 7 | 634
Mammary Neoplasms 7 | 403
Mental Retardation 7 | 634
Mental deficiency 7 | 634
Poor school performance 7 | 634
dermatomyositis 7 | 941
medulloblastoma 7 | 702
progressive supranuclear palsy 7 | 656
Bipolar Disorder 6 | 646
Diarrhea 6 | 245
Duchenne muscular dystrophy 6 | 587
Endometriosis 6 | 521
Epilepsy 6 | 775
Hypertensive disease 6 | 278
Multiple myeloma 6 | 1,296
Polycystic ovary syndrome 6 | 348
acute myeloid leukemia 6 | 760
aldosterone-producing adenoma 6 | 646
non primary Sjogren syndrome sicca 6 | 861
primary Sjogren syndrome 6 | 710
Alzheimer's disease 5 | 640
Cataract 5 | 290
Cerebrovascular disease 5 | 223
Muscle hypotonia 5 | 562
Rheumatoid arthritis 5 | 1,156
Seizures 5 | 584
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 492
chronic rhinosinusitis 5 | 505
fibroadenoma 5 | 538
mucosa-associated lymphoid tissue lymphoma 5 | 473
nephrosclerosis 5 | 314
periodontitis 5 | 280

Tissue

Digestive Tract 116 | 17,369
Endocrine System 116 | 18,159
Female tissues 116 | 17,400
Urinary Tract 115 | 16,678
Skin and soft tissues 114 | 17,230
Male tissues 113 | 17,142
Nervous System 111 | 16,725
Respiratory system 111 | 16,393
Blood and immune system 110 | 16,909
Liver and Pancreas 110 | 16,750
Cardiovascular System 105 | 15,192

Target Family

Non-IDG 105 | 12,091
Enzyme 11 | 4,145
Kinase 4 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Occluding junction 122 | 122
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Afadin AFDN Tbio Non-IDG -2.16280 151.2 200
Tight junction protein ZO-3 TJP3 Tbio Non-IDG -1.36150 19.9 173
Putative claudin-25 CLDN25 Tdark Non-IDG 0.30 0.20 37
Claudin-5 CLDN5 Tbio Non-IDG -2.58968 349.4 300
Partitioning defective 3 homolog B PARD3B Tbio Non-IDG -0.83869 7.22 31
Cytohesin-1 CYTH1 Tbio Non-IDG -2.10475 140.2 194
FERM domain-containing protein 4A FRMD4A Tbio Non-IDG -0.91432 9.82 34
Claudin-14 CLDN14 Tbio Non-IDG -1.58115 36.2 206
Coxsackievirus and adenovirus receptor CXADR Tbio Non-IDG -2.47204 284.9 320
Nance-Horan syndrome protein NHS Tbio Non-IDG -1.85132 68.2 16