Development Level

Tbio 5,108 | 11,651
Tdark 1,605 | 6,593
Tchem 666 | 1,388
Tclin 184 | 612

Collection

RFA-RM-18-021 90 | 328
Kinase: IDG Consortium (Target... 69 | 125
Kinase: IDG Consortium (Comple... 25 | 37
Ion Channel: IDG Consortium (T... 11 | 99
GPCR: IDG Consortium (Targets) 10 | 126
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 557 | 979
preweaning lethality, incomple... 217 | 499
embryonic lethality prior to t... 152 | 278
embryonic lethality prior to o... 134 | 239
abnormal behavior 122 | 298
abnormal embryo size 117 | 220
abnormal bone structure 95 | 187
decreased total body fat amoun... 89 | 207
enlarged heart 81 | 210
decreased vertical activity 80 | 208
decreased body weight 79 | 161
increased lean body mass 78 | 172
decreased lean body mass 71 | 135
hypoactivity 68 | 132
abnormal heart morphology 65 | 162
decreased bone mineral content 63 | 151
increased total body fat amoun... 63 | 134
increased startle reflex 61 | 112
male infertility 60 | 123
decreased grip strength 56 | 116
increased circulating alkaline... 56 | 122
hyperactivity 54 | 148
decreased bone mineral density 53 | 126
decreased circulating glucose ... 52 | 126
embryonic growth retardation 52 | 106
decreased body length 48 | 101
decreased circulating choleste... 48 | 93
increased mean corpuscular vol... 47 | 92
abnormal seminal vesicle morph... 45 | 114
decreased prepulse inhibition 45 | 82
increased bone mineral content 45 | 108
prenatal lethality prior to he... 43 | 87
decreased lymphocyte cell numb... 41 | 83
increased or absent threshold ... 41 | 101
increased circulating HDL chol... 40 | 80
increased mean corpuscular hem... 40 | 96
cataract 39 | 92
decreased circulating triglyce... 39 | 79
short tibia 39 | 97
decreased leukocyte cell numbe... 37 | 73
decreased mean corpuscular vol... 37 | 79
impaired glucose tolerance 37 | 75
increased circulating choleste... 36 | 66
abnormal lens morphology 35 | 81
increased bone mineral density 35 | 72
abnormal gait 34 | 69
decreased hemoglobin content 34 | 68
increased fasted circulating g... 34 | 76
abnormal coat-hair pigmentatio... 33 | 64
decreased circulating serum al... 33 | 82
edema 33 | 59
female infertility 33 | 60
abnormal kidney morphology 31 | 65
decreased caudal vertebrae num... 31 | 53
decreased circulating HDL chol... 31 | 68
decreased circulating insulin ... 31 | 76
small superior vagus ganglion 31 | 74
decreased erythrocyte cell num... 30 | 62
decreased fasted circulating g... 30 | 65
increased heart weight 30 | 62
abnormal behavioral response t... 28 | 66
improved glucose tolerance 28 | 79
abnormal eye morphology 27 | 68
abnormal retina morphology 27 | 71
decreased startle reflex 27 | 75
increased monocyte cell number 27 | 63
thrombocytopenia 27 | 56
tremors 27 | 39
abnormal spleen morphology 26 | 55
abnormal neural tube closure 25 | 46
decreased blood urea nitrogen ... 25 | 51
decreased mean corpuscular hem... 25 | 50
increased mean platelet volume 25 | 45
small testis 25 | 58
increased circulating sodium l... 24 | 71
increased neutrophil cell numb... 24 | 46
corneal opacity 23 | 32
decreased circulating alkaline... 23 | 46
decreased hematocrit 23 | 46
hydrometra 23 | 53
increased grip strength 23 | 41
abnormal skin morphology 22 | 50
decreased circulating alanine ... 22 | 47
decreased circulating total pr... 22 | 49
increased body length 22 | 32
increased circulating triglyce... 22 | 42
abnormal sleep behavior 21 | 70
decreased neutrophil cell numb... 21 | 42
increased circulating chloride... 21 | 41
increased hemoglobin content 21 | 45
abnormal craniofacial morpholo... 20 | 33
anophthalmia 20 | 33
decreased circulating LDL chol... 20 | 38
increased blood urea nitrogen ... 20 | 48
abnormal cornea morphology 18 | 31
decreased circulating iron lev... 18 | 32
increased circulating creatini... 18 | 38
abnormal bone mineralization 17 | 38
increased hematocrit 17 | 46
increased mean corpuscular hem... 17 | 36

Disease

Carcinoma 4,774 | 11,493
ovarian cancer 3,931 | 8,520
osteosarcoma 3,575 | 7,950
medulloblastoma, large-cell 2,690 | 6,241
psoriasis 2,689 | 6,694
glioblastoma 2,492 | 5,792
lung cancer 2,228 | 4,740
atypical teratoid / rhabdoid tumor 2,181 | 5,112
group 3 medulloblastoma 1,993 | 4,104
ependymoma 1,834 | 4,679
Breast cancer 1,599 | 3,578
malignant mesothelioma 1,561 | 3,232
adult high grade glioma 1,495 | 3,801
Cancer 1,418 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 1,399 | 3,291
primitive neuroectodermal tumor 1,363 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 1,263 | 2,989
oligodendroglioma 1,233 | 2,850
invasive ductal carcinoma 1,231 | 2,951
non-small cell lung cancer 1,193 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 1,154 | 2,955
Astrocytoma, Pilocytic 1,089 | 3,081
Kidney cancer 1,089 | 2,613
astrocytic glioma 1,071 | 2,597
lung adenocarcinoma 1,052 | 2,716
pancreatic cancer 961 | 2,398
subependymal giant cell astrocytoma 924 | 2,287
lung carcinoma 914 | 2,843
Pick disease 839 | 1,894
group 4 medulloblastoma 813 | 1,855
tuberculosis 787 | 2,010
pituitary cancer 773 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 763 | 1,962
interstitial cystitis 751 | 2,312
Multiple myeloma 732 | 1,332
ductal carcinoma in situ 720 | 1,745
breast carcinoma 711 | 1,638
diabetes mellitus 673 | 1,728
adrenocortical carcinoma 671 | 1,428
ulcerative colitis 663 | 1,819
colon cancer 650 | 1,478
cystic fibrosis 617 | 1,696
acute quadriplegic myopathy 597 | 1,158
Rheumatoid arthritis 589 | 1,191
juvenile dermatomyositis 573 | 1,187
astrocytoma 559 | 1,146
Intellectual disability 532 | 1,016
Autosomal recessive predisposition 523 | 1,442
dermatomyositis 510 | 966
Schizophrenia 490 | 1,160
spina bifida 479 | 1,074
pediatric high grade glioma 476 | 1,064
Waldenstrons macroglobulinemia 462 | 765
primary pancreatic ductal adenocarcinoma 456 | 1,109
nasopharyngeal carcinoma 438 | 1,058
cutaneous lupus erythematosus 423 | 1,057
acute myeloid leukemia 411 | 783
non primary Sjogren syndrome sicca 388 | 891
Atopic dermatitis 363 | 952
Dull intelligence 332 | 645
Low intelligence 332 | 645
Mental Retardation 332 | 645
Mental deficiency 332 | 645
Poor school performance 332 | 645
primary Sjogren syndrome 326 | 735
progressive supranuclear palsy 325 | 676
Epilepsy 322 | 792
active Crohn's disease 321 | 922
aldosterone-producing adenoma 313 | 665
Obesity 306 | 678
Alzheimer's disease 305 | 658
Cognitive delay 301 | 608
Global developmental delay 301 | 608
Mental and motor retardation 301 | 608
medulloblastoma 297 | 720
Liver Cirrhosis, Experimental 293 | 769
gastric carcinoma 292 | 807
Short stature 285 | 531
Breast Neoplasms 281 | 445
esophageal adenocarcinoma 281 | 737
Bipolar Disorder 278 | 666
Endometriosis 276 | 540
active ulcerative colitis 272 | 764
hepatocellular carcinoma 270 | 547
Seizures 269 | 596
Mammary Neoplasms 268 | 425
Prostatic Neoplasms 258 | 495
Amyotrophic lateral sclerosis 247 | 451
Muscle hypotonia 244 | 571
Melanoma 239 | 711
Down syndrome 236 | 499
Liver cancer 235 | 604
pancreatic carcinoma 235 | 562
tuberculosis and treatment for 6 months 223 | 409
sonic hedgehog group medulloblastoma 219 | 467
autosomal dominant Emery-Dreifuss muscular dystrophy 217 | 510
gastric cancer 216 | 459
Small head 215 | 374
Duchenne muscular dystrophy 212 | 601
Depressive disorder 206 | 409

Tissue

Endocrine System 7,372 | 18,159
Digestive Tract 7,193 | 17,369
Female tissues 7,166 | 17,400
Skin and soft tissues 7,163 | 17,230
Male tissues 7,140 | 17,142
Blood and immune system 7,060 | 16,909
Nervous System 7,049 | 16,725
Liver and Pancreas 7,030 | 16,750
Urinary Tract 7,021 | 16,678
Respiratory system 6,962 | 16,393
Cardiovascular System 6,668 | 15,192

Target Family

Non-IDG 3,903 | 12,091
Enzyme 1,485 | 4,145
Transcription Factor 1,376 | 1,400
Kinase 351 | 634
Epigenetic 216 | 242
Transporter 63 | 473
Nuclear Receptor 47 | 48
GPCR 45 | 408
Ion Channel 40 | 344
TF/Epigenetic 37 | 38

Compartment GO Term

Nucleus 7,563 | 7,563
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.51747 3.15 91
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Pyrin domain-containing protein 1 PYDC1 Tbio Non-IDG -2.88567 750.0 115
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
DNA-binding death effector domain-containing protein 2 DEDD2 Tbio Non-IDG -0.55115 3.37 164
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Serine/arginine-rich splicing factor 12 SRSF12 Tbio Non-IDG -0.09691 1.17 22