Development Level

Tbio 868 | 11,651
Tchem 125 | 1,388
Tdark 95 | 6,593
Tclin 34 | 612

Collection

Kinase: IDG Consortium (Target... 9 | 125
Kinase: IDG Consortium (Comple... 5 | 37
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 135 | 979
preweaning lethality, incomple... 44 | 499
embryonic lethality prior to o... 36 | 239
embryonic lethality prior to t... 35 | 278
abnormal embryo size 27 | 220
abnormal behavior 21 | 298
decreased total body fat amoun... 19 | 207
increased startle reflex 15 | 112
decreased body weight 14 | 161
increased lean body mass 14 | 172
cataract 13 | 92
hypoactivity 13 | 132
abnormal lens morphology 12 | 81
enlarged heart 12 | 210
abnormal heart morphology 11 | 162
decreased bone mineral density 11 | 126
increased total body fat amoun... 11 | 134
decreased lean body mass 10 | 135
decreased leukocyte cell numbe... 10 | 73
decreased vertical activity 10 | 208
decreased body length 9 | 101
decreased bone mineral content 9 | 151
increased bone mineral content 9 | 108
increased mean corpuscular vol... 9 | 92
decreased grip strength 8 | 116
decreased hemoglobin content 8 | 68
embryonic growth retardation 8 | 106
increased bone mineral density 8 | 72
increased circulating HDL chol... 8 | 80
male infertility 8 | 123
prenatal lethality prior to he... 8 | 87
abnormal bone structure 7 | 187
abnormal gait 7 | 69
abnormal retina morphology 7 | 71
corneal opacity 7 | 32
decreased circulating choleste... 7 | 93
decreased circulating glucose ... 7 | 126
hyperactivity 7 | 148
increased body length 7 | 32
increased circulating alkaline... 7 | 122
increased mean corpuscular hem... 7 | 96
abnormal eye morphology 6 | 68
decreased erythrocyte cell num... 6 | 62
decreased prepulse inhibition 6 | 82
increased circulating sodium l... 6 | 71
increased fasted circulating g... 6 | 76
abnormal bone mineralization 5 | 38
abnormal seminal vesicle morph... 5 | 114
decreased circulating HDL chol... 5 | 68
decreased circulating iron lev... 5 | 32
decreased lymphocyte cell numb... 5 | 83
increased body weight 5 | 25
increased circulating choleste... 5 | 66
increased grip strength 5 | 41
increased mean corpuscular hem... 5 | 36
increased mean platelet volume 5 | 45
increased monocyte cell number 5 | 63
thrombocytopenia 5 | 56
tremors 5 | 39
abnormal cornea morphology 4 | 31
decreased caudal vertebrae num... 4 | 53
decreased circulating LDL chol... 4 | 38
decreased circulating alanine ... 4 | 47
decreased circulating alkaline... 4 | 46
decreased circulating aspartat... 4 | 34
decreased circulating insulin ... 4 | 76
decreased circulating serum al... 4 | 82
decreased fasted circulating g... 4 | 65
decreased hematocrit 4 | 46
decreased total retina thickne... 4 | 17
edema 4 | 59
female infertility 4 | 60
impaired glucose tolerance 4 | 75
increased circulating calcium ... 4 | 34
increased circulating serum al... 4 | 22
increased heart weight 4 | 62
increased or absent threshold ... 4 | 101
pallor 4 | 34
persistence of hyaloid vascula... 4 | 33
short tibia 4 | 97
small testis 4 | 58
vertebral transformation 4 | 12
abnormal coat-hair pigmentatio... 3 | 64
abnormal heart left ventricle ... 3 | 16
abnormal neural tube closure 3 | 46
abnormal skin morphology 3 | 50
anophthalmia 3 | 33
cardiovascular system phenotyp... 3 | 36
decreased circulating triglyce... 3 | 79
decreased eosinophil cell numb... 3 | 24
decreased lactate dehydrogenas... 3 | 16
decreased red blood cell distr... 3 | 41
enlarged spleen 3 | 41
increased circulating amylase ... 3 | 25
increased circulating chloride... 3 | 41
increased circulating potassiu... 3 | 29
increased circulating total pr... 3 | 28
increased hemoglobin content 3 | 45
microphthalmia 3 | 26
pale yolk sac 3 | 25

Disease

Carcinoma 773 | 11,493
ovarian cancer 690 | 8,520
osteosarcoma 600 | 7,950
psoriasis 429 | 6,694
medulloblastoma, large-cell 400 | 6,241
glioblastoma 381 | 5,792
lung cancer 365 | 4,740
group 3 medulloblastoma 335 | 4,104
atypical teratoid / rhabdoid tumor 325 | 5,112
Cancer 301 | 2,499
malignant mesothelioma 278 | 3,232
Breast cancer 274 | 3,578
ependymoma 265 | 4,679
Kidney cancer 226 | 2,613
adult high grade glioma 218 | 3,801
primitive neuroectodermal tumor 216 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 199 | 3,291
oligodendroglioma 196 | 2,850
non-small cell lung cancer 178 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 173 | 2,989
Multiple myeloma 168 | 1,332
invasive ductal carcinoma 166 | 2,951
astrocytic glioma 158 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 156 | 2,955
lung adenocarcinoma 145 | 2,716
pancreatic cancer 142 | 2,398
Pick disease 140 | 1,894
Astrocytoma, Pilocytic 133 | 3,081
Intellectual disability 132 | 1,016
subependymal giant cell astrocytoma 130 | 2,287
tuberculosis 128 | 2,010
astrocytoma 123 | 1,146
diabetes mellitus 118 | 1,728
acute quadriplegic myopathy 114 | 1,158
Rheumatoid arthritis 109 | 1,191
dermatomyositis 109 | 966
pituitary cancer 109 | 1,972
lung carcinoma 108 | 2,843
juvenile dermatomyositis 106 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 105 | 1,962
Waldenstrons macroglobulinemia 103 | 765
group 4 medulloblastoma 101 | 1,855
breast carcinoma 100 | 1,638
ductal carcinoma in situ 99 | 1,745
acute myeloid leukemia 97 | 783
adrenocortical carcinoma 95 | 1,428
ulcerative colitis 95 | 1,819
colon cancer 85 | 1,478
Dull intelligence 83 | 645
Low intelligence 83 | 645
Mental Retardation 83 | 645
Mental deficiency 83 | 645
Poor school performance 83 | 645
Short stature 81 | 531
interstitial cystitis 80 | 2,312
Autosomal recessive predisposition 77 | 1,442
Schizophrenia 77 | 1,160
spina bifida 73 | 1,074
Cognitive delay 72 | 608
Global developmental delay 72 | 608
Mental and motor retardation 72 | 608
pediatric high grade glioma 72 | 1,064
primary pancreatic ductal adenocarcinoma 69 | 1,109
Breast Neoplasms 68 | 445
Mammary Neoplasms 66 | 425
Small head 61 | 374
non primary Sjogren syndrome sicca 61 | 891
Prostatic Neoplasms 60 | 495
progressive supranuclear palsy 59 | 676
Liver cancer 58 | 604
Endometriosis 57 | 540
cystic fibrosis 56 | 1,696
nasopharyngeal carcinoma 56 | 1,058
hepatocellular carcinoma 55 | 547
Epilepsy 53 | 792
cutaneous lupus erythematosus 52 | 1,057
primary Sjogren syndrome 52 | 735
Obesity 51 | 678
Melanoma 50 | 711
Seizures 50 | 596
Muscle hypotonia 49 | 571
tuberculosis and treatment for 6 months 49 | 409
Alzheimer's disease 46 | 658
Amyotrophic lateral sclerosis 45 | 451
Cryptorchidism 44 | 296
aldosterone-producing adenoma 44 | 665
Anemia 43 | 365
Atopic dermatitis 43 | 952
Bipolar Disorder 43 | 666
Strabismus 42 | 270
medulloblastoma 42 | 720
Hypoplastic mandible condyle 41 | 275
Mandibular hypoplasia 41 | 275
Micrognathism 41 | 275
Acquired scoliosis 40 | 281
Curvature of spine 40 | 282
Neurodegenerative disease 40 | 414
Stomach Neoplasms 40 | 300
autosomal dominant Emery-Dreifuss muscular dystrophy 39 | 510
gastric carcinoma 39 | 807

Tissue

Endocrine System 1,101 | 18,159
Female tissues 1,097 | 17,400
Digestive Tract 1,093 | 17,369
Male tissues 1,093 | 17,142
Skin and soft tissues 1,090 | 17,230
Blood and immune system 1,086 | 16,909
Liver and Pancreas 1,086 | 16,750
Nervous System 1,086 | 16,725
Respiratory system 1,084 | 16,393
Urinary Tract 1,082 | 16,678
Cardiovascular System 1,059 | 15,192

Target Family

Non-IDG 603 | 12,091
Enzyme 234 | 4,145
Transcription Factor 113 | 1,400
Epigenetic 88 | 242
Kinase 56 | 634
Nuclear Receptor 11 | 48
TF/Epigenetic 11 | 38
GPCR 2 | 408
Ion Channel 2 | 344
Transporter 2 | 473

Compartment GO Term

Nucleoplasm part 1,122 | 1,122
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Eukaryotic translation initiation factor 4E transporter EIF4ENIF1 Tbio Non-IDG -1.60874 36.7 242
ETS-related transcription factor Elf-2 ELF2 Tbio Transcription Factor -2.04794 106.4 92
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.65323 46.0 231
Tripeptidyl-peptidase 2 TPP2 Tbio Enzyme -1.97332 108.2 72