Development Level

Tbio 138 | 10,625
Tdark 79 | 7,003
Tchem 20 | 1,890
Tclin 2 | 602

Collection

Eligible Kinase Proteins 3 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal behavior 3 | 226
abnormal behavioral response t... 3 | 52
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
abnormal sleep behavior 2 | 63
decreased body weight 2 | 174
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased startle reflex 2 | 48
hyperactivity 2 | 108
increased lean body mass 2 | 107
increased or absent threshold ... 2 | 128
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal kidney morphology 1 | 30
abnormal maxilla morphology 1 | 16
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
anophthalmia 1 | 20
decreased NK cell number 1 | 16
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating sodium l... 1 | 18
decreased cornea thickness 1 | 2
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased lactate dehydrogenas... 1 | 14
decreased lumbar vertebrae num... 1 | 62
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged pancreas 1 | 1
increased B cell number 1 | 23
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
microphthalmia 1 | 15
oligodactyly 1 | 14
preweaning lethality, incomple... 1 | 260
prolonged PQ interval 1 | 3
prolonged ST segment 1 | 4
short tibia 1 | 82
small testis 1 | 37

Disease

osteosarcoma 114 | 7,933
ovarian cancer 112 | 8,492
glioblastoma 88 | 5,572
medulloblastoma, large-cell 82 | 6,234
psoriasis 73 | 6,685
lung cancer 67 | 4,473
atypical teratoid / rhabdoid tumor 63 | 4,369
malignant mesothelioma 56 | 3,163
primitive neuroectodermal tumor 52 | 3,031
invasive ductal carcinoma 42 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
pediatric high grade glioma 41 | 2,712
lung carcinoma 39 | 2,844
adult high grade glioma 38 | 2,148
Breast cancer 37 | 3,099
pilocytic astrocytoma 37 | 3,086
oligodendroglioma 36 | 2,849
non-small cell lung cancer 35 | 2,798
subependymal giant cell astrocytoma 35 | 2,287
group 3 medulloblastoma 34 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,956
lung adenocarcinoma 33 | 2,714
ependymoma 32 | 2,514
astrocytic glioma 30 | 2,241
Cancer 29 | 2,346
interstitial cystitis 27 | 2,299
group 4 medulloblastoma 26 | 1,875
medulloblastoma 25 | 1,524
Carcinoma 24 | 2,147
ductal carcinoma in situ 23 | 1,745
Multiple myeloma 21 | 1,328
cystic fibrosis 21 | 1,670
posterior fossa group B ependymoma 21 | 1,530
sonic hedgehog group medulloblastoma 21 | 1,482
pituitary cancer 20 | 1,972
pancreatic cancer 19 | 2,300
posterior fossa group A ependymoma 19 | 1,511
tuberculosis 18 | 1,563
ulcerative colitis 18 | 2,087
Pick disease 17 | 1,893
Waldenstrons macroglobulinemia 17 | 765
astrocytoma 17 | 1,493
breast carcinoma 17 | 1,614
colon cancer 17 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
spina bifida 16 | 1,064
cutaneous lupus erythematosus 15 | 1,056
primary pancreatic ductal adenocarcinoma 15 | 1,271
aldosterone-producing adenoma 14 | 664
atypical teratoid/rhabdoid tumor 14 | 1,095
diabetes mellitus 14 | 1,663
juvenile dermatomyositis 14 | 1,189
adrenocortical carcinoma 13 | 1,427
acute quadriplegic myopathy 12 | 1,157
active Crohn's disease 11 | 918
acute myeloid leukemia 11 | 785
dermatomyositis 11 | 967
non primary Sjogren syndrome sicca 11 | 840
primary Sjogren syndrome 11 | 789
Atopic dermatitis 10 | 944
nasopharyngeal carcinoma 10 | 1,056
Amyotrophic Lateral Sclerosis 9 | 432
Prostatic Neoplasms 9 | 471
Rheumatoid Arthritis 9 | 1,171
Obesity 8 | 616
chronic rhinosinusitis 8 | 512
progressive supranuclear palsy 8 | 674
Intellectual disability 7 | 573
gastric carcinoma 7 | 832
inflammatory breast cancer 7 | 404
tuberculosis and treatment for 3 months 7 | 327
Acquired metabolic disease 6 | 267
Alzheimer's disease 6 | 644
Down syndrome 6 | 548
Duchenne muscular dystrophy 6 | 602
Mammary Neoplasms 6 | 410
Stomach Neoplasms 6 | 282
active ulcerative colitis 6 | 477
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
fibroadenoma 6 | 557
gastric cancer 6 | 436
non-small cell lung carcinoma 6 | 413
tuberculosis and treatment for 6 months 6 | 686
Crohn's disease 5 | 304
Systemic scleroderma 5 | 66
hepatocellular carcinoma 5 | 550
pancreatic carcinoma 5 | 567
sarcoidosis 5 | 368
systemic lupus erythematosus 5 | 172
Becker muscular dystrophy 4 | 187
Endometriosis 4 | 535
Microcephaly 4 | 149
Prostate cancer 4 | 172
Vascular disease 4 | 281
esophageal adenocarcinoma 4 | 737
glioblastoma multiforme 4 | 347
hereditary spastic paraplegia 4 | 313
interstitial lung disease 4 | 292
mucosa-associated lymphoid tissue lymphoma 3 | 480

Tissue

Digestive Tract 238 | 18,473
Male tissues 238 | 17,969
Nervous System 238 | 18,561
Endocrine System 237 | 18,512
Liver and Pancreas 237 | 18,136
Female tissues 236 | 18,647
Urinary Tract 235 | 18,444
Blood and immune system 234 | 17,995
Cardiovascular System 234 | 17,958
Skin and soft tissues 234 | 18,115
Respiratory system 233 | 17,484

Target Family

Non-IDG 142 | 11,969
Enzyme 43 | 4,146
Transcription Factor 31 | 1,400
Kinase 11 | 634
Epigenetic 5 | 242
TF/Epigenetic 3 | 38
Ion Channel 2 | 341
Nuclear Receptor 1 | 48
Transporter 1 | 473

Compartment GO Term

Nucleoli fibrillar center 239 | 239
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hexosaminidase D HEXDC Tbio Enzyme -0.60206 3.23 55
Sperm protein associated with the nucleus on the X chromosome N2 SPANXN2 Tdark Non-IDG 0.26 0.25 6
Sperm protein associated with the nucleus on the X chromosome N3 SPANXN3 Tdark Non-IDG 0.85 0.05 7
Protein arginine N-methyltransferase 7 PRMT7 Tbio Epigenetic -1.25720 20.4 136
Double zinc ribbon and ankyrin repeat-containing protein 1 DZANK1 Tdark Non-IDG 0.08 1.00 14
Ankyrin repeat and EF-hand domain-containing protein 1 ANKEF1 Tdark Non-IDG 0.19 0.39 72
AF4/FMR2 family member 4 AFF4 Tbio Transcription Factor -2.52668 332.1 141
Crossover junction endonuclease MUS81 MUS81 Tbio Enzyme -2.03597 106.6 73
Krueppel-like factor 6 KLF6 Tbio Transcription Factor -2.33566 239.4 148
Y-box-binding protein 2 YBX2 Tbio Transcription Factor -1.95593 88.2 208