Development Level

Tbio 150 | 11,651
Tdark 69 | 6,593
Tchem 17 | 1,388
Tclin 2 | 612

Collection

RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Target... 3 | 125
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 6 | 499
abnormal embryo size 5 | 220
embryonic lethality prior to t... 5 | 278
abnormal behavior 4 | 298
abnormal sleep behavior 4 | 70
abnormal behavioral response t... 3 | 66
decreased startle reflex 3 | 75
decreased total body fat amoun... 3 | 207
embryonic growth retardation 3 | 106
increased lean body mass 3 | 172
increased or absent threshold ... 3 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating choleste... 2 | 93
decreased circulating sodium l... 2 | 22
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
increased circulating alkaline... 2 | 122
increased prepulse inhibition 2 | 32
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal posture 1 | 2
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
anophthalmia 1 | 33
brachydactyly 1 | 19
cataract 1 | 92
decreased anxiety-related resp... 1 | 12
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
enlarged pancreas 1 | 2
female infertility 1 | 60
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased aggression 1 | 4
increased basophil cell number 1 | 7
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased caudal vertebrae num... 1 | 7
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
long tibia 1 | 25
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
prolonged PQ interval 1 | 5
prolonged QRS complex duration 1 | 8
prolonged ST segment 1 | 36
short tibia 1 | 97
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 159 | 11,493
osteosarcoma 113 | 7,950
ovarian cancer 112 | 8,520
glioblastoma 91 | 5,792
medulloblastoma, large-cell 82 | 6,241
atypical teratoid / rhabdoid tumor 72 | 5,112
psoriasis 72 | 6,694
lung cancer 69 | 4,740
group 3 medulloblastoma 59 | 4,104
adult high grade glioma 58 | 3,801
ependymoma 58 | 4,679
malignant mesothelioma 56 | 3,232
primitive neuroectodermal tumor 52 | 3,035
invasive ductal carcinoma 42 | 2,951
Breast cancer 41 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
lung carcinoma 39 | 2,843
Astrocytoma, Pilocytic 37 | 3,081
non-small cell lung cancer 36 | 2,890
oligodendroglioma 36 | 2,850
subependymal giant cell astrocytoma 35 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
lung adenocarcinoma 33 | 2,716
astrocytic glioma 32 | 2,597
Cancer 31 | 2,499
Kidney cancer 31 | 2,613
group 4 medulloblastoma 29 | 1,855
interstitial cystitis 27 | 2,312
tuberculosis 24 | 2,010
ductal carcinoma in situ 23 | 1,745
Multiple myeloma 22 | 1,332
cystic fibrosis 21 | 1,696
pancreatic cancer 21 | 2,398
pediatric high grade glioma 21 | 1,064
pituitary cancer 20 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Pick disease 17 | 1,894
Waldenstrons macroglobulinemia 17 | 765
breast carcinoma 17 | 1,638
colon cancer 17 | 1,478
spina bifida 16 | 1,074
astrocytoma 15 | 1,146
cutaneous lupus erythematosus 15 | 1,057
ulcerative colitis 15 | 1,819
aldosterone-producing adenoma 14 | 665
diabetes mellitus 14 | 1,728
juvenile dermatomyositis 14 | 1,187
Liver Cirrhosis, Experimental 13 | 769
adrenocortical carcinoma 13 | 1,428
primary pancreatic ductal adenocarcinoma 13 | 1,109
acute quadriplegic myopathy 12 | 1,158
non primary Sjogren syndrome sicca 12 | 891
Intellectual disability 11 | 1,016
active Crohn's disease 11 | 922
acute myeloid leukemia 11 | 783
dermatomyositis 11 | 966
medulloblastoma 11 | 720
Amyotrophic lateral sclerosis 10 | 451
Atopic dermatitis 10 | 952
nasopharyngeal carcinoma 10 | 1,058
primary Sjogren syndrome 10 | 735
Autosomal recessive predisposition 9 | 1,442
Prostatic Neoplasms 9 | 495
Rheumatoid arthritis 9 | 1,191
active ulcerative colitis 9 | 764
posterior fossa group B ependymoma 9 | 416
chronic rhinosinusitis 8 | 512
progressive supranuclear palsy 8 | 676
sonic hedgehog group medulloblastoma 8 | 467
Alzheimer's disease 7 | 658
Breast Neoplasms 7 | 445
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mammary Neoplasms 7 | 425
Mental and motor retardation 7 | 608
Schizophrenia 7 | 1,160
Acquired metabolic disease 6 | 336
Cryptorchidism 6 | 296
Duchenne muscular dystrophy 6 | 601
Endometrial cancer 6 | 311
Liver cancer 6 | 604
Obesity 6 | 678
Small head 6 | 374
Stomach Neoplasms 6 | 300
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
fibroadenoma 6 | 559
gastric cancer 6 | 459
gastric carcinoma 6 | 807
Cerebellar Ataxia 5 | 304
Crohn's disease 5 | 321
Down syndrome 5 | 499
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Short stature 5 | 531
hepatocellular carcinoma 5 | 547
pancreatic carcinoma 5 | 562

Tissue

Endocrine System 238 | 18,159
Digestive Tract 235 | 17,369
Female tissues 235 | 17,400
Male tissues 235 | 17,142
Nervous System 234 | 16,725
Skin and soft tissues 234 | 17,230
Liver and Pancreas 233 | 16,750
Respiratory system 232 | 16,393
Urinary Tract 231 | 16,678
Blood and immune system 230 | 16,909
Cardiovascular System 224 | 15,192

Target Family

Non-IDG 141 | 12,091
Enzyme 43 | 4,145
Transcription Factor 31 | 1,400
Kinase 11 | 634
Epigenetic 5 | 242
TF/Epigenetic 3 | 38
Ion Channel 2 | 344
Nuclear Receptor 1 | 48
Transporter 1 | 473

Compartment GO Term

Nucleoli fibrillar center 238 | 238
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Zinc finger homeobox protein 2 ZFHX2 Tdark Transcription Factor -0.50515 3.13 28
NAD-dependent protein deacetylase sirtuin-7 SIRT7 Tbio Epigenetic -2.22094 153.0 348
Protein FAM111A FAM111A Tbio Non-IDG -0.67981 5.64 27
DNA-directed RNA polymerase I subunit RPA43 TWISTNB Tdark Enzyme -0.05799 1.13 69
H/ACA ribonucleoprotein complex subunit 1 GAR1 Tbio Non-IDG -0.33131 2.70 86
Zinc finger protein 586 ZNF586 Tdark Transcription Factor 0.00000 35
Radical S-adenosyl methionine domain-containing protein 2 RSAD2 Tbio Non-IDG -1.99883 103.3 117
Calcipressin-3 RCAN3 Tbio Non-IDG -0.77232 6.75 203
Origin recognition complex subunit 6 ORC6 Tbio Non-IDG -1.38268 26.3 165