Development Level

Tbio 567 | 11,445
Tdark 296 | 6,588
Tchem 65 | 1,598
Tclin 14 | 613

Collection

RFA-RM-18-021 9 | 328
Kinase: IDG Consortium (Target... 5 | 125
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 63 | 979
preweaning lethality, incomple... 28 | 499
abnormal behavior 13 | 298
abnormal bone structure 13 | 187
abnormal embryo size 13 | 220
decreased vertical activity 13 | 208
embryonic lethality prior to o... 13 | 239
embryonic lethality prior to t... 12 | 278
decreased total body fat amoun... 9 | 207
increased or absent threshold ... 9 | 101
decreased bone mineral content 8 | 151
increased total body fat amoun... 8 | 134
decreased body length 7 | 101
decreased circulating choleste... 7 | 93
enlarged heart 7 | 210
hyperactivity 7 | 148
increased lean body mass 7 | 172
abnormal behavioral response t... 6 | 66
abnormal seminal vesicle morph... 6 | 114
decreased body weight 6 | 161
decreased circulating glucose ... 6 | 126
decreased lean body mass 6 | 135
impaired glucose tolerance 6 | 75
increased circulating HDL chol... 6 | 80
short tibia 6 | 97
abnormal coat-hair pigmentatio... 5 | 64
abnormal heart morphology 5 | 162
abnormal skin morphology 5 | 50
abnormal sleep behavior 5 | 70
abnormal spleen morphology 5 | 55
abnormal vertebrae morphology 5 | 18
decreased circulating alanine ... 5 | 47
decreased grip strength 5 | 116
decreased startle reflex 5 | 75
increased bone mineral content 5 | 108
increased bone mineral density 5 | 72
increased circulating triglyce... 5 | 42
increased startle reflex 5 | 112
male infertility 5 | 123
abnormal coat appearance 4 | 31
abnormal placenta size 4 | 20
cardiovascular system phenotyp... 4 | 36
decreased circulating HDL chol... 4 | 68
decreased circulating insulin ... 4 | 76
decreased circulating triglyce... 4 | 79
decreased fasted circulating g... 4 | 65
decreased mean corpuscular hem... 4 | 50
edema 4 | 59
female infertility 4 | 60
impaired pupillary reflex 4 | 26
increased circulating alkaline... 4 | 122
increased circulating sodium l... 4 | 71
increased fasted circulating g... 4 | 76
prenatal lethality prior to he... 4 | 87
small testis 4 | 58
abnormal cornea morphology 3 | 31
abnormal epididymis morphology 3 | 42
abnormal lens morphology 3 | 81
abnormal vocalization 3 | 21
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 53
decreased circulating chloride... 3 | 30
decreased circulating iron lev... 3 | 32
decreased circulating serum al... 3 | 82
decreased circulating sodium l... 3 | 22
decreased hematocrit 3 | 46
decreased leukocyte cell numbe... 3 | 73
decreased prepulse inhibition 3 | 82
decreased red blood cell distr... 3 | 41
embryonic growth retardation 3 | 106
hemorrhage 3 | 23
hypoactivity 3 | 132
increased circulating chloride... 3 | 41
increased circulating choleste... 3 | 66
increased circulating glucose ... 3 | 24
increased mean corpuscular hem... 3 | 96
prolonged QT interval 3 | 38
shortened RR interval 3 | 17
tremors 3 | 39
abnormal craniofacial morpholo... 2 | 33
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal optic disc morphology 2 | 10
abnormal retina morphology 2 | 71
convulsive seizures 2 | 13
corneal opacity 2 | 32
decreased circulating LDL chol... 2 | 38
decreased circulating creatini... 2 | 39
decreased circulating free fat... 2 | 31
decreased heart rate variabili... 2 | 13
decreased hemoglobin content 2 | 68
enlarged spleen 2 | 41
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
microphthalmia 2 | 26
pale yolk sac 2 | 25
pallor 2 | 34
vertebral fusion 2 | 23

Disease

Carcinoma 567 | 11,493
ovarian cancer 481 | 8,520
osteosarcoma 430 | 7,950
medulloblastoma, large-cell 351 | 6,241
glioblastoma 305 | 5,792
psoriasis 301 | 6,694
atypical teratoid / rhabdoid tumor 271 | 5,112
lung cancer 270 | 4,740
group 3 medulloblastoma 257 | 4,104
ependymoma 219 | 4,679
Breast cancer 192 | 3,578
adult high grade glioma 188 | 3,801
malignant mesothelioma 179 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 170 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 163 | 2,989
invasive ductal carcinoma 159 | 2,951
primitive neuroectodermal tumor 157 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 145 | 2,955
non-small cell lung cancer 142 | 2,890
Astrocytoma, Pilocytic 138 | 3,081
lung adenocarcinoma 136 | 2,716
oligodendroglioma 127 | 2,850
astrocytic glioma 121 | 2,597
subependymal giant cell astrocytoma 119 | 2,287
lung carcinoma 117 | 2,843
Kidney cancer 111 | 2,613
pancreatic cancer 110 | 2,398
Cancer 107 | 2,499
Pick disease 99 | 1,894
group 4 medulloblastoma 96 | 1,855
Multiple myeloma 88 | 1,332
colon cancer 87 | 1,478
ductal carcinoma in situ 86 | 1,745
cystic fibrosis 85 | 1,696
pituitary cancer 85 | 1,972
breast carcinoma 83 | 1,638
interstitial cystitis 82 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 80 | 1,962
tuberculosis 77 | 2,010
adrenocortical carcinoma 76 | 1,428
acute quadriplegic myopathy 74 | 1,158
diabetes mellitus 74 | 1,728
ulcerative colitis 70 | 1,819
dermatomyositis 61 | 966
juvenile dermatomyositis 61 | 1,187
pediatric high grade glioma 57 | 1,064
Waldenstrons macroglobulinemia 56 | 765
Rheumatoid arthritis 54 | 1,191
astrocytoma 54 | 1,146
non primary Sjogren syndrome sicca 53 | 891
spina bifida 51 | 1,074
Autosomal recessive predisposition 49 | 1,442
acute myeloid leukemia 45 | 783
nasopharyngeal carcinoma 44 | 1,058
primary pancreatic ductal adenocarcinoma 43 | 1,109
Intellectual disability 38 | 1,016
cutaneous lupus erythematosus 37 | 1,057
Schizophrenia 35 | 1,160
hepatocellular carcinoma 34 | 547
progressive supranuclear palsy 34 | 676
Atopic dermatitis 32 | 952
active Crohn's disease 32 | 922
medulloblastoma 32 | 720
primary Sjogren syndrome 32 | 735
gastric carcinoma 31 | 807
Alzheimer's disease 30 | 658
Endometriosis 30 | 540
pancreatic carcinoma 30 | 562
Cognitive delay 28 | 608
Down syndrome 28 | 499
Global developmental delay 28 | 608
Liver cancer 28 | 604
Mental and motor retardation 28 | 608
Duchenne muscular dystrophy 27 | 601
aldosterone-producing adenoma 27 | 665
Epilepsy 26 | 792
Melanoma 26 | 711
posterior fossa group A ependymoma 26 | 468
Amyotrophic lateral sclerosis 25 | 451
autosomal dominant Emery-Dreifuss muscular dystrophy 25 | 510
gastric cancer 25 | 459
sonic hedgehog group medulloblastoma 25 | 467
tuberculosis and treatment for 6 months 25 | 409
Dull intelligence 24 | 645
Low intelligence 24 | 645
Mental Retardation 24 | 645
Mental deficiency 24 | 645
Poor school performance 24 | 645
Small head 24 | 374
esophageal adenocarcinoma 24 | 737
fibroadenoma 24 | 559
hereditary spastic paraplegia 23 | 318
posterior fossa group B ependymoma 23 | 416
Liver Cirrhosis, Experimental 22 | 769
Short stature 22 | 531
active ulcerative colitis 22 | 764
atypical teratoid/rhabdoid tumor 22 | 357
Parkinson's disease 21 | 392
Seizures 21 | 596
mucosa-associated lymphoid tissue lymphoma 21 | 484

Tissue

Endocrine System 939 | 18,159
Male tissues 920 | 17,142
Nervous System 920 | 16,725
Digestive Tract 919 | 17,369
Female tissues 918 | 17,400
Skin and soft tissues 918 | 17,230
Liver and Pancreas 915 | 16,750
Respiratory system 911 | 16,393
Blood and immune system 910 | 16,909
Urinary Tract 905 | 16,678
Cardiovascular System 880 | 15,192

Target Family

Non-IDG 560 | 12,091
Enzyme 201 | 4,145
Transcription Factor 110 | 1,400
Kinase 28 | 634
Epigenetic 20 | 242
Transporter 9 | 473
Ion Channel 8 | 344
GPCR 4 | 408
TF/Epigenetic 2 | 38

Compartment GO Term

Nucleoli 942 | 942
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WASH complex subunit 2C WASHC2C Tbio Non-IDG -0.83634 0.00000 45
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Probable dimethyladenosine transferase DIMT1 Tbio Enzyme -0.37946 1.98 103
Securin-2 PTTG2 Tdark Non-IDG -0.58734 3.76 86
60S ribosomal protein L13a RPL13A Tbio Non-IDG -1.64278 64.4 67
Signal recognition particle 14 kDa protein SRP14 Tbio Non-IDG -1.25810 14.5 106
Leydig cell tumor 10 kDa protein homolog C19orf53 Tdark Non-IDG 0.85 0.14 19
FERM domain-containing protein 8 FRMD8 Tdark Non-IDG 0.48 0.20 104
HMG domain-containing protein 3 HMGXB3 Tdark Transcription Factor -0.15127 1.49 73
WD repeat-containing protein 3 WDR3 Tbio Non-IDG -0.73207 4.46 80