Development Level

Tbio 140 | 11,445
Tdark 27 | 6,588
Tchem 15 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 21 | 979
embryonic lethality prior to t... 8 | 278
preweaning lethality, incomple... 7 | 499
embryonic lethality prior to o... 5 | 239
abnormal embryo size 3 | 220
decreased circulating sodium l... 3 | 22
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
embryonic growth retardation 2 | 106
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal posture 1 | 2
abnormal rib morphology 1 | 10
abnormal spine curvature 1 | 9
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased coping response 1 | 8
decreased cornea thickness 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged pancreas 1 | 2
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased aggression 1 | 4
increased cardiac muscle contr... 1 | 8
increased caudal vertebrae num... 1 | 7
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating insulin ... 1 | 3
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
kyphosis 1 | 5
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 128 | 11,493
ovarian cancer 98 | 8,520
osteosarcoma 84 | 7,950
lung cancer 76 | 4,740
psoriasis 70 | 6,694
medulloblastoma, large-cell 65 | 6,241
group 3 medulloblastoma 52 | 4,104
glioblastoma 49 | 5,792
malignant mesothelioma 43 | 3,232
atypical teratoid / rhabdoid tumor 42 | 5,112
adult high grade glioma 37 | 3,801
ependymoma 35 | 4,679
Cancer 34 | 2,499
Breast cancer 32 | 3,578
primitive neuroectodermal tumor 32 | 3,035
invasive ductal carcinoma 31 | 2,951
colon cancer 29 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
non-small cell lung cancer 24 | 2,890
Multiple myeloma 23 | 1,332
lung carcinoma 23 | 2,843
subependymal giant cell astrocytoma 23 | 2,287
lung adenocarcinoma 22 | 2,716
Astrocytoma, Pilocytic 21 | 3,081
Kidney cancer 21 | 2,613
oligodendroglioma 21 | 2,850
acute quadriplegic myopathy 19 | 1,158
astrocytic glioma 18 | 2,597
diabetes mellitus 18 | 1,728
juvenile dermatomyositis 18 | 1,187
pancreatic cancer 18 | 2,398
Waldenstrons macroglobulinemia 17 | 765
cutaneous lupus erythematosus 16 | 1,057
group 4 medulloblastoma 16 | 1,855
tuberculosis 15 | 2,010
Autosomal recessive predisposition 14 | 1,442
Pick disease 14 | 1,894
breast carcinoma 14 | 1,638
astrocytoma 13 | 1,146
interstitial cystitis 13 | 2,312
non primary Sjogren syndrome sicca 13 | 891
pituitary cancer 13 | 1,972
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
cystic fibrosis 12 | 1,696
ductal carcinoma in situ 12 | 1,745
pediatric high grade glioma 12 | 1,064
Intellectual disability 11 | 1,016
Rheumatoid arthritis 11 | 1,191
acute myeloid leukemia 11 | 783
dermatomyositis 11 | 966
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
primary Sjogren syndrome 10 | 735
ulcerative colitis 10 | 1,819
Amyotrophic lateral sclerosis 9 | 451
active Crohn's disease 9 | 922
primary pancreatic ductal adenocarcinoma 9 | 1,109
spina bifida 9 | 1,074
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Prostatic Neoplasms 8 | 495
Small head 8 | 374
Stomach Neoplasms 8 | 300
adrenocortical carcinoma 8 | 1,428
gastric carcinoma 8 | 807
nasopharyngeal carcinoma 8 | 1,058
Adenocarcinoma of lung 7 | 142
Disease Models, Animal 7 | 155
Short stature 7 | 531
Treacher Collins syndrome 7 | 27
aldosterone-producing adenoma 7 | 665
Anemia 6 | 365
Broad flat nasal bridge 6 | 236
Cryptorchidism 6 | 296
Fetal Growth Retardation 6 | 189
Hemoglobin low 6 | 124
Infant, Small for Gestational Age 6 | 176
Intrauterine retardation 6 | 176
Liver Cirrhosis, Experimental 6 | 769
Microcephaly 6 | 166
Nasal bridge wide 6 | 236
Obesity 6 | 678
Schizophrenia 6 | 1,160
Systemic scleroderma 6 | 60
active ulcerative colitis 6 | 764
gastric cancer 6 | 459
hepatocellular carcinoma 6 | 547
medulloblastoma 6 | 720
mucosa-associated lymphoid tissue lymphoma 6 | 484
pancreatic carcinoma 6 | 562
progressive supranuclear palsy 6 | 676
sonic hedgehog group medulloblastoma 6 | 467
Cleft Palate 5 | 271
Micrognathism 5 | 275

Tissue

Endocrine System 181 | 18,159
Female tissues 181 | 17,400
Skin and soft tissues 181 | 17,230
Blood and immune system 180 | 16,909
Digestive Tract 180 | 17,369
Liver and Pancreas 180 | 16,750
Male tissues 180 | 17,142
Respiratory system 180 | 16,393
Urinary Tract 180 | 16,678
Nervous System 179 | 16,725
Cardiovascular System 176 | 15,192

Target Family

Non-IDG 107 | 12,091
Enzyme 43 | 4,145
Transcription Factor 19 | 1,400
Kinase 8 | 634
Epigenetic 4 | 242
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

Compartment GO Term

Nucleolar part 184 | 184
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Methylthioribose-1-phosphate isomerase MRI1 Tbio Enzyme -2.37285 221.6 146
Ribosomal protein S6 kinase alpha-6 RPS6KA6 Tchem Kinase -1.26563 21.6 158
U3 small nucleolar RNA-associated protein 18 homolog UTP18 Tdark Non-IDG -0.50488 2.92 52
Mitochondrial import inner membrane translocase subunit Tim13 TIMM13 Tbio Enzyme -1.90930 75.7 32
Sestrin-1 SESN1 Tbio Non-IDG -1.95681 82.0 172
Protein arginine N-methyltransferase 7 PRMT7 Tchem Epigenetic -1.32370 24.3 163
Treacle protein TCOF1 Tbio Non-IDG -3.44117 2743.5 131
Krueppel-like factor 6 KLF6 Tbio Transcription Factor -2.37304 253.6 161
BTB/POZ domain-containing protein 10 BTBD10 Tbio Non-IDG -0.47192 5.30 152