Development Level

Tbio 84 | 11,445
Tclin 16 | 613
Tchem 11 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 17 | 979
embryonic lethality prior to t... 6 | 278
embryonic lethality prior to o... 4 | 239
abnormal embryo size 3 | 220
increased heart weight 3 | 62
abnormal gait 2 | 69
decreased circulating glucose ... 2 | 126
embryonic growth retardation 2 | 106
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
aorta dilation 1 | 3
decreased basophil cell number 1 | 16
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased mature B cell number 1 | 7
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating calcium ... 1 | 34
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
shortened QT interval 1 | 4

Disease

Carcinoma 68 | 11,493
ovarian cancer 59 | 8,520
osteosarcoma 54 | 7,950
medulloblastoma, large-cell 44 | 6,241
lung cancer 40 | 4,740
psoriasis 40 | 6,694
glioblastoma 34 | 5,792
Autosomal recessive predisposition 32 | 1,442
group 3 medulloblastoma 30 | 4,104
Cerebellar Ataxia 28 | 304
atypical teratoid / rhabdoid tumor 27 | 5,112
diabetes mellitus 27 | 1,728
Acidosis, Lactic 25 | 97
Cancer 25 | 2,499
Lactic acidemia 25 | 95
Neuropathy 24 | 261
ependymoma 24 | 4,679
Breast cancer 22 | 3,578
adult high grade glioma 21 | 3,801
Multiple myeloma 20 | 1,332
Muscle hypotonia 20 | 571
Cognitive delay 19 | 608
Epilepsy 19 | 792
Global developmental delay 19 | 608
Mental and motor retardation 19 | 608
Mitochondrial myopathy 19 | 26
Sensorineural Hearing Loss (disorder) 19 | 284
Blepharoptosis 18 | 231
Optic Atrophy 18 | 242
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Failure to gain weight 17 | 365
Heart failure 17 | 162
Leigh disease 17 | 100
Myopathy 17 | 185
Pediatric failure to thrive 17 | 365
Short stature 17 | 531
non-small cell lung cancer 17 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Peripheral Neuropathy 16 | 134
Schizophrenia 16 | 1,160
Seizures 16 | 596
lung adenocarcinoma 16 | 2,716
malignant mesothelioma 16 | 3,232
primitive neuroectodermal tumor 16 | 3,035
Lactic acidosis 15 | 51
Polyneuropathy 14 | 64
Ragged-red fibers 14 | 21
astrocytic glioma 14 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
pancreatic cancer 14 | 2,398
Depressive disorder 13 | 409
Diabetes Mellitus, Non-Insulin-Dependent 13 | 145
Dystonia 13 | 164
Increased serum lactate 13 | 60
Mitochondrial Myopathies 13 | 21
Obesity 13 | 678
colon cancer 13 | 1,478
oligodendroglioma 13 | 2,850
tuberculosis 13 | 2,010
ulcerative colitis 13 | 1,819
Chronic progressive external ophthalmoplegia 12 | 26
Creatine phosphokinase serum increased 12 | 110
Dystonic disease 12 | 106
Elevated creatine kinase 12 | 110
Highly variable severity 12 | 157
Hypertensive disease 12 | 292
Leber hereditary optic neuropathy 12 | 14
Muscle Weakness 12 | 170
Variable expressivity 12 | 157
cystic fibrosis 12 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
invasive ductal carcinoma 12 | 2,951
Astrocytoma, Pilocytic 11 | 3,081
Blind spot located at fixation point 11 | 21
Brain Ischemia 11 | 110
Cachexia 11 | 50
Cerebral atrophy 11 | 178
Decreased visual acuity, slowly progressive 11 | 13
Dull intelligence 11 | 645
Electrocardiogram abnormal 11 | 81
Hepatomegaly 11 | 285
Intellectual disability 11 | 1,016
Kidney cancer 11 | 2,613
Low intelligence 11 | 645
MELAS syndrome 11 | 18
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Mitochondrial respiratory chain defects 11 | 15
Neurodegenerative disease 11 | 414
Nystagmus 11 | 317
Ophthalmoplegia 11 | 106
Pick disease 11 | 1,894
Poor school performance 11 | 645
Scotoma, Central 11 | 21
Slow decrease in visual acuity 11 | 13
interstitial cystitis 11 | 2,312
Dementia 10 | 175
Hypoglycemia 10 | 152
Loss of developmental milestones 10 | 95
lung carcinoma 10 | 2,843

Tissue

Endocrine System 112 | 18,159
Blood and immune system 111 | 16,909
Digestive Tract 111 | 17,369
Female tissues 111 | 17,400
Skin and soft tissues 111 | 17,230
Nervous System 110 | 16,725
Urinary Tract 110 | 16,678
Liver and Pancreas 109 | 16,750
Male tissues 109 | 17,142
Respiratory system 109 | 16,393
Cardiovascular System 107 | 15,192

Target Family

Enzyme 55 | 4,145
Non-IDG 47 | 12,091
Transcription Factor 5 | 1,400
Transporter 3 | 473
Kinase 2 | 634
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

Compartment GO Term

Nucleoid 115 | 115
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATPase family AAA domain-containing protein 3A ATAD3A Tbio Enzyme -1.10725 16.5 114
Ubiquinol-cytochrome-c reductase complex assembly factor 2 UQCC2 Tbio Enzyme -1.53008 34.4 21
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.86910 750.8 255
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
G-rich sequence factor 1 GRSF1 Tbio Non-IDG -1.05585 12.0 138
Pendrin SLC26A4 Tbio Transporter -2.69164 501.3 100
Pre-B-cell leukemia transcription factor 2 PBX2 Tbio Transcription Factor -1.90701 75.7 168
Transcriptional activator protein Pur-alpha PURA Tbio Non-IDG -2.17708 158.7 170
Tumor necrosis factor receptor superfamily member 25 TNFRSF25 Tbio Non-IDG -3.25237 1888.2 535
Cytochrome b MT-CYB Tbio Non-IDG -3.77047 5856.5 134