Development Level

Tbio 64 | 11,445
Tchem 13 | 1,598
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 17 | 979
abnormal embryo size 7 | 220
embryonic lethality prior to t... 7 | 278
embryonic lethality prior to o... 5 | 239
abnormal heart morphology 4 | 162
embryonic growth retardation 4 | 106
abnormal bone structure 3 | 187
anophthalmia 3 | 33
increased mean corpuscular vol... 3 | 92
abnormal behavior 2 | 298
abnormal craniofacial morpholo... 2 | 33
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
cataract 2 | 92
decreased caudal vertebrae num... 2 | 53
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating magnesiu... 2 | 13
edema 2 | 59
enlarged heart 2 | 210
female infertility 2 | 60
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
male infertility 2 | 123
microphthalmia 2 | 26
preweaning lethality, incomple... 2 | 499
small spleen 2 | 19
small testis 2 | 58
abnormal bone mineralization 1 | 38
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart looping 1 | 5
abnormal hindbrain morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal midbrain development 1 | 20
abnormal midbrain morphology 1 | 10
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta morphology 1 | 5
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
brachydactyly 1 | 19
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased basophil cell number 1 | 7
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased total body fat amoun... 1 | 134
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
small kidney 1 | 16
syndactyly 1 | 23
thrombocytosis 1 | 27
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

ovarian cancer 54 | 8,520
Carcinoma 48 | 11,493
glioblastoma 41 | 5,792
medulloblastoma, large-cell 39 | 6,241
psoriasis 39 | 6,694
osteosarcoma 37 | 7,950
atypical teratoid / rhabdoid tumor 35 | 5,112
group 3 medulloblastoma 34 | 4,104
Breast cancer 32 | 3,578
Cancer 32 | 2,499
lung cancer 31 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
primitive neuroectodermal tumor 27 | 3,035
invasive ductal carcinoma 26 | 2,951
non-small cell lung cancer 26 | 2,890
adrenocortical carcinoma 24 | 1,428
adult high grade glioma 24 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
lung adenocarcinoma 23 | 2,716
ependymoma 22 | 4,679
malignant mesothelioma 22 | 3,232
ductal carcinoma in situ 20 | 1,745
breast carcinoma 19 | 1,638
colon cancer 16 | 1,478
pancreatic cancer 16 | 2,398
oligodendroglioma 15 | 2,850
Kidney cancer 14 | 2,613
Atopic dermatitis 13 | 952
Endometriosis 13 | 540
Intellectual disability 11 | 1,016
astrocytic glioma 11 | 2,597
nasopharyngeal carcinoma 11 | 1,058
Astrocytoma, Pilocytic 10 | 3,081
Multiple myeloma 9 | 1,332
Short stature 9 | 531
Small head 9 | 374
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary Sjogren syndrome 9 | 735
tuberculosis 9 | 2,010
ulcerative colitis 9 | 1,819
Cognitive delay 8 | 608
Dull intelligence 8 | 645
Global developmental delay 8 | 608
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental and motor retardation 8 | 608
Mental deficiency 8 | 645
Poor school performance 8 | 645
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
medulloblastoma 8 | 720
Rheumatoid arthritis 7 | 1,191
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
posterior fossa group A ependymoma 7 | 468
primary pancreatic ductal adenocarcinoma 7 | 1,109
subependymal giant cell astrocytoma 7 | 2,287
Pick disease 6 | 1,894
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,158
lung carcinoma 6 | 2,843
pediatric high grade glioma 6 | 1,064
Acquired metabolic disease 5 | 336
Autosomal recessive predisposition 5 | 1,442
Breast Neoplasms 5 | 445
Cataract 5 | 297
Glaucoma 5 | 239
Hypoplastic mandible condyle 5 | 275
Lens Opacities 5 | 231
Mammary Neoplasms 5 | 425
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
esophageal adenocarcinoma 5 | 737
Abnormally small eyeball 4 | 97
Concave bridge of nose 4 | 195
Congenital Epicanthus 4 | 177
Decreased size of eyeball 4 | 97
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Long philtrum 4 | 137
Microphthalmos 4 | 100
Penile hypospadias 4 | 106
Triangular face 4 | 58
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
non primary Sjogren syndrome sicca 4 | 891
pituitary cancer 4 | 1,972
sonic hedgehog group medulloblastoma 4 | 467
Curvature of spine 3 | 282
Epilepsy 3 | 792
Prostate cancer 3 | 175
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Seizures 3 | 596
aldosterone-producing adenoma 3 | 665
diabetes mellitus 3 | 1,728
fibroadenoma 3 | 559

Tissue

Blood and immune system 83 | 16,909
Digestive Tract 83 | 17,369
Endocrine System 83 | 18,159
Female tissues 83 | 17,400
Male tissues 83 | 17,142
Liver and Pancreas 82 | 16,750
Skin and soft tissues 82 | 17,230
Nervous System 81 | 16,725
Respiratory system 81 | 16,393
Urinary Tract 80 | 16,678
Cardiovascular System 78 | 15,192

Target Family

Non-IDG 47 | 12,091
Enzyme 22 | 4,145
Epigenetic 9 | 242
Kinase 5 | 634

Compartment GO Term

Nuclear ubiquitin ligase compl... 83 | 83
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional prefoldin RPB5 interactor 1 URI1 Tbio Enzyme -2.15409 134.8 150
RING finger protein 222 RNF222 Tdark Non-IDG 0.00000 4
Polycomb group RING finger protein 1 PCGF1 Tbio Non-IDG -0.99091 11.4 101
Chromobox protein homolog 8 CBX8 Tchem Epigenetic -2.27537 183.4 505
Polycomb group RING finger protein 3 PCGF3 Tdark Non-IDG -0.48328 1.97 115
Serine incorporator 3 SERINC3 Tbio Non-IDG -2.44903 264.3 131
Chromobox protein homolog 2 CBX2 Tchem Epigenetic -1.37369 24.3 223
Anaphase-promoting complex subunit 10 ANAPC10 Tbio Enzyme -1.23751 18.1 156
Anaphase-promoting complex subunit 11 ANAPC11 Tbio Enzyme -1.27406 17.9 239
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166