Development Level

Tbio 264 | 11,651
Tdark 113 | 6,593
Tchem 29 | 1,388
Tclin 6 | 612

Collection

Kinase: IDG Consortium (Target... 5 | 125
Kinase: IDG Consortium (Comple... 4 | 37
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 40 | 979
preweaning lethality, incomple... 14 | 499
embryonic lethality prior to t... 9 | 278
embryonic lethality prior to o... 7 | 239
abnormal lens morphology 6 | 81
increased startle reflex 6 | 112
cataract 5 | 92
decreased total body fat amoun... 5 | 207
abnormal behavior 4 | 298
decreased body weight 4 | 161
decreased vertical activity 4 | 208
enlarged heart 4 | 210
abnormal behavioral response t... 3 | 66
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased hemoglobin content 3 | 68
decreased leukocyte cell numbe... 3 | 73
increased bone mineral density 3 | 72
increased heart weight 3 | 62
increased lean body mass 3 | 172
increased monocyte cell number 3 | 63
persistence of hyaloid vascula... 3 | 33
short tibia 3 | 97
abnormal bone mineralization 2 | 38
abnormal brain morphology 2 | 13
abnormal coat-hair pigmentatio... 2 | 64
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal iris morphology 2 | 13
abnormal neural tube morpholog... 2 | 12
abnormal placement of pupils 2 | 6
abnormal skin coloration 2 | 25
abnormal startle reflex 2 | 15
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased mean corpuscular vol... 2 | 79
decreased mean platelet volume 2 | 25
hemorrhage 2 | 23
hypoactivity 2 | 132
increased anti-nuclear antigen... 2 | 19
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased total body fat amoun... 2 | 134
irregularly shaped pupil 2 | 7
limb grasping 2 | 41
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal coat- hair morphology 1 | 19
abnormal heart left ventricle ... 1 | 16
abnormal locomotor activation 1 | 16
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
polycystic kidney 1 | 15
small testis 1 | 58

Disease

Carcinoma 276 | 11,493
ovarian cancer 231 | 8,520
osteosarcoma 226 | 7,950
glioblastoma 149 | 5,792
medulloblastoma, large-cell 149 | 6,241
psoriasis 141 | 6,694
atypical teratoid / rhabdoid tumor 126 | 5,112
ependymoma 126 | 4,679
lung cancer 119 | 4,740
group 3 medulloblastoma 116 | 4,104
adult high grade glioma 92 | 3,801
malignant mesothelioma 90 | 3,232
Breast cancer 80 | 3,578
primitive neuroectodermal tumor 80 | 3,035
oligodendroglioma 79 | 2,850
astrocytic glioma 73 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 68 | 3,291
Kidney cancer 67 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 67 | 2,989
invasive ductal carcinoma 66 | 2,951
non-small cell lung cancer 64 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 63 | 2,955
Astrocytoma, Pilocytic 59 | 3,081
group 4 medulloblastoma 56 | 1,855
lung carcinoma 53 | 2,843
Cancer 51 | 2,499
Pick disease 51 | 1,894
lung adenocarcinoma 49 | 2,716
tuberculosis 48 | 2,010
Multiple myeloma 47 | 1,332
subependymal giant cell astrocytoma 47 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 43 | 1,962
juvenile dermatomyositis 39 | 1,187
acute quadriplegic myopathy 36 | 1,158
interstitial cystitis 36 | 2,312
pancreatic cancer 36 | 2,398
astrocytoma 34 | 1,146
ductal carcinoma in situ 32 | 1,745
progressive supranuclear palsy 32 | 676
adrenocortical carcinoma 31 | 1,428
pituitary cancer 31 | 1,972
dermatomyositis 30 | 966
diabetes mellitus 30 | 1,728
ulcerative colitis 29 | 1,819
Rheumatoid arthritis 27 | 1,191
Intellectual disability 26 | 1,016
pediatric high grade glioma 26 | 1,064
spina bifida 26 | 1,074
Waldenstrons macroglobulinemia 25 | 765
cystic fibrosis 24 | 1,696
hepatocellular carcinoma 24 | 547
non primary Sjogren syndrome sicca 24 | 891
breast carcinoma 23 | 1,638
acute myeloid leukemia 21 | 783
Schizophrenia 19 | 1,160
colon cancer 19 | 1,478
Atopic dermatitis 18 | 952
Autosomal recessive predisposition 18 | 1,442
nasopharyngeal carcinoma 18 | 1,058
primary pancreatic ductal adenocarcinoma 18 | 1,109
Short stature 16 | 531
primary Sjogren syndrome 16 | 735
tuberculosis and treatment for 6 months 16 | 409
Alzheimer's disease 15 | 658
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Mental and motor retardation 15 | 608
chronic rhinosinusitis 15 | 512
cutaneous lupus erythematosus 15 | 1,057
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
Amyotrophic lateral sclerosis 13 | 451
Bipolar Disorder 13 | 666
Down syndrome 13 | 499
Dull intelligence 13 | 645
Gaucher disease type 1 13 | 180
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
gastric cancer 13 | 459
Liver cancer 12 | 604
Muscle hypotonia 12 | 571
Adenoid Cystic Carcinoma 11 | 99
Carcinoma, Adenoid Cystic 11 | 99
Depressive disorder 11 | 409
Low set ears 11 | 181
Melanoma 11 | 711
active Crohn's disease 11 | 922
aldosterone-producing adenoma 11 | 665
atypical teratoid/rhabdoid tumor 11 | 357
medulloblastoma 11 | 720
pancreatic carcinoma 11 | 562
Cataract 10 | 297
Duchenne muscular dystrophy 10 | 601
Hypoplastic mandible condyle 10 | 275
Mandibular hypoplasia 10 | 275
Micrognathism 10 | 275
Prostatic Neoplasms 10 | 495
gastric carcinoma 10 | 807
sonic hedgehog group medulloblastoma 10 | 467

Tissue

Endocrine System 411 | 18,159
Female tissues 408 | 17,400
Male tissues 408 | 17,142
Skin and soft tissues 408 | 17,230
Nervous System 406 | 16,725
Digestive Tract 405 | 17,369
Liver and Pancreas 404 | 16,750
Blood and immune system 403 | 16,909
Urinary Tract 403 | 16,678
Respiratory system 397 | 16,393
Cardiovascular System 391 | 15,192

Target Family

Non-IDG 241 | 12,091
Enzyme 69 | 4,145
Transcription Factor 51 | 1,400
Kinase 25 | 634
Epigenetic 15 | 242
GPCR 3 | 408
Transporter 3 | 473
Ion Channel 2 | 344
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

Compartment GO Term

Nuclear speckles 412 | 412
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263
RNA-binding protein 39 RBM39 Tbio Non-IDG -0.95639 9.80 199
Zinc finger protein 169 ZNF169 Tbio Transcription Factor 0.09 1.17 112
Pre-mRNA-splicing factor SYF2 SYF2 Tbio Non-IDG -1.04825 13.2 124
Corepressor interacting with RBPJ 1 CIR1 Tdark Non-IDG -0.30821 2.08 91
Coiled-coil domain-containing protein 32 CCDC32 Tdark Non-IDG 0.70 0.13 17
Growth arrest-specific protein 1 GAS1 Tbio Non-IDG -2.04247 116.8 144
SPIN1-docking protein SPINDOC Tdark Non-IDG 0.60 0.05 29