Development Level

Tbio 300 | 11,651
Tchem 38 | 1,388
Tdark 32 | 6,593
Tclin 6 | 612

Collection

Kinase: IDG Consortium (Target... 6 | 125
RFA-RM-18-021 6 | 328
Kinase: IDG Consortium (Comple... 3 | 37

IMPC Phenotype

preweaning lethality, complete... 49 | 979
preweaning lethality, incomple... 13 | 499
embryonic lethality prior to o... 11 | 239
embryonic lethality prior to t... 11 | 278
abnormal embryo size 10 | 220
decreased total body fat amoun... 7 | 207
decreased hemoglobin content 6 | 68
decreased body weight 5 | 161
enlarged heart 5 | 210
increased lean body mass 5 | 172
increased startle reflex 5 | 112
abnormal behavior 4 | 298
abnormal heart morphology 4 | 162
decreased body length 4 | 101
decreased circulating alanine ... 4 | 47
decreased circulating iron lev... 4 | 32
decreased erythrocyte cell num... 4 | 62
decreased leukocyte cell numbe... 4 | 73
decreased vertical activity 4 | 208
prenatal lethality prior to he... 4 | 87
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating aspartat... 3 | 34
decreased grip strength 3 | 116
decreased hematocrit 3 | 46
decreased lean body mass 3 | 135
decreased prepulse inhibition 3 | 82
embryonic growth retardation 3 | 106
increased blood urea nitrogen ... 3 | 48
increased bone mineral density 3 | 72
increased fasted circulating g... 3 | 76
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
limb grasping 3 | 41
pallor 3 | 34
abnormal locomotor activation 2 | 16
abnormal neural tube morpholog... 2 | 12
abnormal seminal vesicle morph... 2 | 114
abnormal startle reflex 2 | 15
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased mean platelet volume 2 | 25
edema 2 | 59
female infertility 2 | 60
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating amylase ... 2 | 25
increased circulating calcium ... 2 | 34
increased circulating serum al... 2 | 22
increased heart weight 2 | 62
increased mean platelet volume 2 | 45
male infertility 2 | 123
persistence of hyaloid vascula... 2 | 33
small testis 2 | 58
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal gait 1 | 69
abnormal retina morphology 1 | 71
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased food intake 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
prenatal lethality 1 | 28
small thymus 1 | 16
thrombocytosis 1 | 27

Disease

Carcinoma 268 | 11,493
ovarian cancer 245 | 8,520
osteosarcoma 213 | 7,950
psoriasis 153 | 6,694
glioblastoma 136 | 5,792
medulloblastoma, large-cell 136 | 6,241
lung cancer 122 | 4,740
group 3 medulloblastoma 119 | 4,104
atypical teratoid / rhabdoid tumor 109 | 5,112
ependymoma 101 | 4,679
Breast cancer 89 | 3,578
malignant mesothelioma 88 | 3,232
oligodendroglioma 83 | 2,850
adult high grade glioma 82 | 3,801
Kidney cancer 75 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 70 | 2,989
astrocytic glioma 68 | 2,597
Cancer 67 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 66 | 3,291
Multiple myeloma 65 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 64 | 2,955
primitive neuroectodermal tumor 63 | 3,035
invasive ductal carcinoma 59 | 2,951
non-small cell lung cancer 58 | 2,890
Pick disease 55 | 1,894
Astrocytoma, Pilocytic 48 | 3,081
pancreatic cancer 48 | 2,398
subependymal giant cell astrocytoma 47 | 2,287
dermatomyositis 46 | 966
Waldenstrons macroglobulinemia 45 | 765
acute quadriplegic myopathy 45 | 1,158
lung adenocarcinoma 45 | 2,716
astrocytoma 43 | 1,146
juvenile dermatomyositis 43 | 1,187
tuberculosis 42 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 40 | 1,962
lung carcinoma 39 | 2,843
Rheumatoid arthritis 37 | 1,191
diabetes mellitus 36 | 1,728
group 4 medulloblastoma 36 | 1,855
pituitary cancer 36 | 1,972
progressive supranuclear palsy 35 | 676
ductal carcinoma in situ 34 | 1,745
acute myeloid leukemia 30 | 783
interstitial cystitis 30 | 2,312
Intellectual disability 29 | 1,016
adrenocortical carcinoma 29 | 1,428
ulcerative colitis 28 | 1,819
breast carcinoma 27 | 1,638
primary pancreatic ductal adenocarcinoma 27 | 1,109
spina bifida 27 | 1,074
primary Sjogren syndrome 24 | 735
pediatric high grade glioma 21 | 1,064
colon cancer 20 | 1,478
tuberculosis and treatment for 6 months 20 | 409
Autosomal recessive predisposition 19 | 1,442
hepatocellular carcinoma 19 | 547
non primary Sjogren syndrome sicca 19 | 891
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Poor school performance 18 | 645
Schizophrenia 17 | 1,160
cutaneous lupus erythematosus 17 | 1,057
sonic hedgehog group medulloblastoma 17 | 467
Amyotrophic lateral sclerosis 16 | 451
Short stature 16 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 510
nasopharyngeal carcinoma 16 | 1,058
Alzheimer's disease 15 | 658
Osteoporosis 15 | 363
active Crohn's disease 15 | 922
cystic fibrosis 15 | 1,696
Atopic dermatitis 14 | 952
aldosterone-producing adenoma 14 | 665
gastric cancer 14 | 459
Bipolar Disorder 13 | 666
Hypogonadism 13 | 173
Obesity 13 | 678
Prostatic Neoplasms 13 | 495
posterior fossa group B ependymoma 13 | 416
Anteverted nostril 12 | 191
Broad flat nasal bridge 12 | 236
Cognitive delay 12 | 608
Down syndrome 12 | 499
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Muscle hypotonia 12 | 571
Nasal bridge wide 12 | 236
pancreatic carcinoma 12 | 562
Cataract 11 | 297
Depressive disorder 11 | 409
Duchenne muscular dystrophy 11 | 601
Endometriosis 11 | 540
Hypoplastic mandible condyle 11 | 275
Mandibular hypoplasia 11 | 275
Micrognathism 11 | 275
Small head 11 | 374
Unipolar Depression 11 | 250

Tissue

Endocrine System 371 | 18,159
Digestive Tract 369 | 17,369
Male tissues 368 | 17,142
Female tissues 367 | 17,400
Liver and Pancreas 367 | 16,750
Nervous System 367 | 16,725
Skin and soft tissues 367 | 17,230
Blood and immune system 366 | 16,909
Urinary Tract 364 | 16,678
Respiratory system 363 | 16,393
Cardiovascular System 358 | 15,192

Target Family

Non-IDG 212 | 12,091
Enzyme 73 | 4,145
Transcription Factor 37 | 1,400
Kinase 26 | 634
Epigenetic 19 | 242
Nuclear Receptor 4 | 48
TF/Epigenetic 2 | 38
Transporter 2 | 473
GPCR 1 | 408

Compartment GO Term

Nuclear speck 376 | 376
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Eukaryotic translation initiation factor 4E transporter EIF4ENIF1 Tbio Non-IDG -1.60874 36.7 242
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69
RNA-binding protein 39 RBM39 Tbio Non-IDG -0.95639 9.80 199
WW domain-containing adapter protein with coiled-coil WAC Tbio Non-IDG -1.93384 84.9 87
Transcriptional repressor p66-beta GATAD2B Tbio Transcription Factor -1.00210 9.37 215