Development Level

Tbio 36 | 10,625
Tchem 10 | 1,890
Tclin 5 | 602
Tdark 3 | 7,003

IMPC Term

preweaning lethality, complete... 7 | 633
embryonic lethality prior to o... 4 | 148
increased circulating sodium l... 3 | 71
embryonic lethality prior to t... 2 | 187
abnormal blood vessel morpholo... 1 | 2
abnormal heart morphology 1 | 51
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
decreased circulating glucose ... 1 | 121
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
enlarged heart 1 | 111
increased circulating alkaline... 1 | 119
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
small testis 1 | 37

Disease

ovarian cancer 32 | 8,484
malignant mesothelioma 28 | 3,162
Cancer 26 | 2,346
lung cancer 26 | 4,466
medulloblastoma, large-cell 24 | 6,234
Breast cancer 22 | 3,094
group 3 medulloblastoma 22 | 2,254
osteosarcoma 22 | 7,933
primitive neuroectodermal tumor 22 | 3,031
psoriasis 22 | 6,685
glioblastoma 19 | 5,572
non-small cell lung cancer 18 | 2,798
pediatric high grade glioma 18 | 2,712
atypical teratoid / rhabdoid tumor 17 | 4,369
colon cancer 15 | 1,475
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
Carcinoma 11 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
sonic hedgehog group medulloblastoma 10 | 1,482
Bloom syndrome 9 | 30
Cockayne syndrome 9 | 54
Fanconi's anemia 9 | 50
Nijmegen breakage syndrome 9 | 23
diabetes mellitus 9 | 1,663
posterior fossa group A ependymoma 9 | 1,511
Ataxia telangiectasia 8 | 31
Mammary Neoplasms 8 | 410
Werner syndrome 8 | 29
Xeroderma pigmentosum 8 | 41
adrenocortical carcinoma 8 | 1,427
ductal carcinoma in situ 8 | 1,745
invasive ductal carcinoma 8 | 2,950
nasopharyngeal carcinoma 8 | 1,056
Colorectal Neoplasms 7 | 217
Peripheral Neuropathy 7 | 303
Seckel syndrome 7 | 34
Waldenstrons macroglobulinemia 7 | 765
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
oligodendroglioma 7 | 2,849
ulcerative colitis 7 | 2,087
lung adenocarcinoma 6 | 2,713
lung carcinoma 6 | 2,844
pilocytic astrocytoma 6 | 3,086
Lynch syndrome 5 | 33
Photosensitive trichothiodystrophy 5 | 24
Stomach Neoplasms 5 | 282
non primary Sjogren syndrome sicca 5 | 840
pancreatic cancer 5 | 2,300
posterior fossa group B ependymoma 5 | 1,530
tuberculosis 5 | 1,557
Anemia 4 | 252
Bladder Neoplasm 4 | 109
Breast Cancer, Familial 4 | 12
Chronic Lymphocytic Leukemia 4 | 242
Endometriosis 4 | 535
Hereditary Breast and Ovarian Cancer Syndrome 4 | 14
IGA Glomerulonephritis 4 | 454
Intellectual disability 4 | 573
Malignant tumor of ovary 4 | 25
Neoplastic Syndromes, Hereditary 4 | 48
Pancreatic Neoplasm 4 | 79
Prostatic Neoplasms 4 | 471
astrocytic glioma 4 | 2,241
astrocytoma 4 | 1,493
atypical teratoid/rhabdoid tumor 4 | 1,095
cystic fibrosis 4 | 1,665
pancreatic carcinoma 4 | 567
subependymal giant cell astrocytoma 4 | 2,287
Acute lymphoid leukemia 3 | 25
Acute myeloid leukemia, disease 3 | 16
Adenocarcinoma of pancreas 3 | 12
Arsenic Poisoning 3 | 59
Atopic dermatitis 3 | 944
Familial adenomatous polyposis 3 | 31
Kidney cancer 3 | 118
Kidney disease 3 | 396
Li-Fraumeni Syndrome 3 | 13
Lung Neoplasms 3 | 171
Lymphomatous meningitis 3 | 3
Malignant neoplasm of breast 3 | 63
Malignant neoplasm of lung 3 | 16
Malignant neoplasm of prostate 3 | 67
Melanoma 3 | 261
Meningeal Leukemia 3 | 7
Metastatic Breast Carcinoma 3 | 21
Neoplasm Metastasis 3 | 138
Pick disease 3 | 1,893
Prostate cancer 3 | 172
Rothmund-Thomson syndrome 3 | 22
acute quadriplegic myopathy 3 | 1,157
breast carcinoma 3 | 1,614
ependymoma 3 | 2,514
glioblastoma multiforme 3 | 347
group 4 medulloblastoma 3 | 1,875
hepatocellular carcinoma 3 | 532
juvenile dermatomyositis 3 | 1,189
non-small cell lung carcinoma 3 | 413
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 674

Tissue

Blood and immune system 54 | 17,995
Cardiovascular System 54 | 17,958
Digestive Tract 54 | 18,473
Endocrine System 54 | 18,512
Female tissues 54 | 18,647
Liver and Pancreas 54 | 18,136
Male tissues 54 | 17,969
Nervous System 54 | 18,561
Respiratory system 54 | 17,484
Skin and soft tissues 54 | 18,115
Urinary Tract 54 | 18,444

Target Family

Non-IDG 25 | 11,971
Enzyme 23 | 4,146
Kinase 4 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Nuclear replisome 54 | 54
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.59332 3912.4 208
ATP-dependent DNA helicase Q1 RECQL Tbio Enzyme -1.84578 76.6 72
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188
DNA repair protein complementing XP-A cells XPA Tbio Non-IDG -2.82887 674.6 301
DNA primase small subunit PRIM1 Tbio Enzyme -0.88906 8.05 121
Replication protein A 14 kDa subunit RPA3 Tbio Non-IDG -1.80635 59.3 127
Transcriptional activator protein Pur-alpha PURA Tbio Non-IDG -2.13635 153.6 155
Ewing's tumor-associated antigen 1 ETAA1 Tdark Non-IDG -0.54200 6.95 37
DNA replication ATP-dependent helicase/nuclease DNA2 DNA2 Tbio Enzyme -2.37310 239.3 81