Development Level

Tbio 41 | 11,445
Tchem 9 | 1,598
Tclin 5 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 3 | 499
abnormal blood vessel morpholo... 2 | 5
abnormal heart morphology 2 | 162
decreased circulating glucose ... 2 | 126
increased circulating sodium l... 2 | 71
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal rib morphology 1 | 10
abnormal somite shape 1 | 5
abnormal spinal cord morpholog... 1 | 9
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
cardiovascular system phenotyp... 1 | 36
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 35 | 11,493
ovarian cancer 35 | 8,520
group 3 medulloblastoma 34 | 4,104
malignant mesothelioma 31 | 3,232
lung cancer 30 | 4,740
Cancer 27 | 2,499
medulloblastoma, large-cell 26 | 6,241
Breast cancer 25 | 3,578
primitive neuroectodermal tumor 25 | 3,035
atypical teratoid / rhabdoid tumor 23 | 5,112
glioblastoma 23 | 5,792
psoriasis 23 | 6,694
osteosarcoma 22 | 7,950
non-small cell lung cancer 20 | 2,890
colon cancer 16 | 1,478
ependymoma 15 | 4,679
adult high grade glioma 14 | 3,801
Xeroderma pigmentosum 13 | 43
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
Kidney cancer 12 | 2,613
Fanconi anemia 11 | 56
adrenocortical carcinoma 11 | 1,428
Autosomal recessive predisposition 10 | 1,442
Bloom syndrome 10 | 29
Nijmegen breakage syndrome 10 | 24
Ataxia telangiectasia 9 | 34
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
Short stature 9 | 531
Werner syndrome 9 | 29
diabetes mellitus 9 | 1,728
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
Dull intelligence 8 | 645
Intellectual disability 8 | 1,016
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
lung adenocarcinoma 8 | 2,716
nasopharyngeal carcinoma 8 | 1,058
oligodendroglioma 8 | 2,850
pediatric high grade glioma 8 | 1,064
Astrocytoma, Pilocytic 7 | 3,081
Colorectal Neoplasms 7 | 243
Seckel syndrome 7 | 34
Waldenstrons macroglobulinemia 7 | 765
ulcerative colitis 7 | 1,819
Cockayne syndrome 6 | 60
Epilepsy 6 | 792
Schizophrenia 6 | 1,160
Seizures 6 | 596
Small head 6 | 374
breast carcinoma 6 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Chromosome Breakage 5 | 36
Cognitive delay 5 | 608
Convex nasal ridge 5 | 37
Cryptorchidism 5 | 296
Endometriosis 5 | 540
Global developmental delay 5 | 608
Lung Neoplasms 5 | 232
Lynch syndrome 5 | 35
Mental and motor retardation 5 | 608
Pancreatic Neoplasm 5 | 85
Prostatic Neoplasms 5 | 495
Thrombocytopenia 5 | 197
astrocytic glioma 5 | 2,597
non primary Sjogren syndrome sicca 5 | 891
Acquired scoliosis 4 | 281
Adenocarcinoma of pancreas 4 | 14
Anemia 4 | 365
Atopic dermatitis 4 | 952
Chronic Lymphocytic Leukemia 4 | 262
Curvature of spine 4 | 282
Endometrial cancer 4 | 311
Fetal Growth Retardation 4 | 189
Hereditary Breast and Ovarian Cancer Syndrome 4 | 14
Hypoplastic mandible condyle 4 | 275
Increased chromosomal breakage 4 | 27
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Liver cancer 4 | 604
Malignant tumor of ovary 4 | 25
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Myocardial Infarction 4 | 151
Pancreatic Neoplasms 4 | 85
Stomach Neoplasms 4 | 300
Strabismus 4 | 270
Telangiectasis 4 | 36
cystic fibrosis 4 | 1,696
hepatocellular carcinoma 4 | 547
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
subependymal giant cell astrocytoma 4 | 2,287
juvenile dermatomyositis 3 | 1,187

Tissue

Blood and immune system 57 | 16,909
Digestive Tract 57 | 17,369
Endocrine System 57 | 18,159
Female tissues 57 | 17,400
Liver and Pancreas 57 | 16,750
Male tissues 57 | 17,142
Nervous System 57 | 16,725
Respiratory system 57 | 16,393
Skin and soft tissues 57 | 17,230
Urinary Tract 57 | 16,678
Cardiovascular System 56 | 15,192

Target Family

Non-IDG 27 | 12,091
Enzyme 24 | 4,145
Kinase 4 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Nuclear replisome 57 | 57
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcriptional activator protein Pur-beta PURB Tbio Non-IDG -1.49692 30.7 79
Ewing's tumor-associated antigen 1 ETAA1 Tbio Non-IDG -0.76616 7.50 40
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
DNA polymerase delta subunit 4 POLD4 Tbio Enzyme -0.84887 7.32 24
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
Transcriptional activator protein Pur-alpha PURA Tbio Non-IDG -2.17708 158.7 170
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248
Replication protein A 14 kDa subunit RPA3 Tbio Non-IDG -1.85941 67.1 171
ATP-dependent DNA helicase Q1 RECQL Tbio Enzyme -1.87053 80.0 73