Development Level

Tbio 49 | 11,651
Tchem 10 | 1,388
Tclin 5 | 612
Tdark 4 | 6,593

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
abnormal behavior 2 | 298
abnormal blood vessel morpholo... 2 | 5
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
decreased circulating glucose ... 2 | 126
increased circulating sodium l... 2 | 71
increased mean corpuscular vol... 2 | 92
prenatal lethality 2 | 28
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal rib morphology 1 | 10
abnormal somite shape 1 | 5
abnormal spinal cord morpholog... 1 | 9
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased circulating alanine ... 1 | 47
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 43 | 11,493
ovarian cancer 42 | 8,520
group 3 medulloblastoma 40 | 4,104
lung cancer 35 | 4,740
medulloblastoma, large-cell 35 | 6,241
malignant mesothelioma 34 | 3,232
primitive neuroectodermal tumor 31 | 3,035
Breast cancer 30 | 3,578
atypical teratoid / rhabdoid tumor 29 | 5,112
glioblastoma 29 | 5,792
osteosarcoma 29 | 7,950
psoriasis 29 | 6,694
Cancer 28 | 2,499
non-small cell lung cancer 26 | 2,890
adult high grade glioma 19 | 3,801
colon cancer 18 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
ependymoma 16 | 4,679
Kidney cancer 15 | 2,613
adrenocortical carcinoma 14 | 1,428
lung adenocarcinoma 14 | 2,716
Xeroderma pigmentosum 13 | 43
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
invasive ductal carcinoma 13 | 2,951
Autosomal recessive predisposition 11 | 1,442
Fanconi anemia 11 | 56
nasopharyngeal carcinoma 11 | 1,058
Bloom syndrome 10 | 29
Nijmegen breakage syndrome 10 | 24
Short stature 10 | 531
breast carcinoma 10 | 1,638
Ataxia telangiectasia 9 | 34
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
Werner syndrome 9 | 29
diabetes mellitus 9 | 1,728
oligodendroglioma 9 | 2,850
Dull intelligence 8 | 645
Intellectual disability 8 | 1,016
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Waldenstrons macroglobulinemia 8 | 765
pediatric high grade glioma 8 | 1,064
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
Colorectal Neoplasms 7 | 243
Endometriosis 7 | 540
Schizophrenia 7 | 1,160
Seckel syndrome 7 | 34
lung carcinoma 7 | 2,843
tuberculosis 7 | 2,010
Atopic dermatitis 6 | 952
Cockayne syndrome 6 | 60
Cognitive delay 6 | 608
Epilepsy 6 | 792
Global developmental delay 6 | 608
Lung Neoplasms 6 | 232
Mental and motor retardation 6 | 608
Seizures 6 | 596
Small head 6 | 374
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
pancreatic cancer 6 | 2,398
Chromosome Breakage 5 | 36
Convex nasal ridge 5 | 37
Cryptorchidism 5 | 296
Lynch syndrome 5 | 35
Pancreatic Neoplasm 5 | 85
Prostatic Neoplasms 5 | 495
Rothmund-Thomson syndrome 5 | 19
Thrombocytopenia 5 | 197
non primary Sjogren syndrome sicca 5 | 891
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Acquired scoliosis 4 | 281
Anemia 4 | 365
Chronic Lymphocytic Leukemia 4 | 262
Curvature of spine 4 | 282
Endometrial cancer 4 | 311
Fetal Growth Retardation 4 | 189
Hypoplastic mandible condyle 4 | 275
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Liver cancer 4 | 604
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Myocardial Infarction 4 | 151
Pancreatic Neoplasms 4 | 85
Pick disease 4 | 1,894
Stomach Neoplasms 4 | 300
Strabismus 4 | 270
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Blood and immune system 68 | 16,909
Digestive Tract 68 | 17,369
Endocrine System 68 | 18,159
Female tissues 68 | 17,400
Liver and Pancreas 68 | 16,750
Male tissues 68 | 17,142
Nervous System 68 | 16,725
Respiratory system 68 | 16,393
Skin and soft tissues 68 | 17,230
Urinary Tract 68 | 16,678
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 25 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400

Compartment GO Term

Nuclear replication fork 68 | 68
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATR-interacting protein ATRIP Tbio Non-IDG -1.60828 43.0 359
CST complex subunit TEN1 TEN1 Tbio Non-IDG -2.18182 142.0 8
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.06760 110.4 225
Chromosome transmission fidelity protein 18 homolog CHTF18 Tbio Non-IDG -1.51235 35.5 138
TIMELESS-interacting protein TIPIN Tbio Non-IDG -1.44126 28.4 246
Sister chromatid cohesion protein DCC1 DSCC1 Tbio Non-IDG -1.10259 11.9 144
Flap endonuclease 1 FEN1 Tchem Enzyme -2.79171 617.0 406
Cell cycle checkpoint control protein RAD9A RAD9A Tbio Non-IDG -2.15330 141.0 919
RPA-interacting protein RPAIN Tbio Non-IDG -1.41218 24.1 153
DNA polymerase delta subunit 2 POLD2 Tbio Enzyme -0.95222 8.52 115