Development Level

Tbio 79 | 11,651
Tdark 12 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal midbrain morphology 1 | 10
abnormal motor capabilities-co... 1 | 5
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
cataract 1 | 92
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating lipase l... 1 | 3
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased circulating serum al... 1 | 22
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
syndactyly 1 | 23

Disease

Carcinoma 74 | 11,493
ovarian cancer 54 | 8,520
osteosarcoma 47 | 7,950
lung cancer 39 | 4,740
medulloblastoma, large-cell 39 | 6,241
group 3 medulloblastoma 33 | 4,104
psoriasis 31 | 6,694
atypical teratoid / rhabdoid tumor 28 | 5,112
glioblastoma 28 | 5,792
ependymoma 22 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Breast cancer 20 | 3,578
dermatomyositis 20 | 966
malignant mesothelioma 20 | 3,232
Cancer 18 | 2,499
non-small cell lung cancer 18 | 2,890
oligodendroglioma 18 | 2,850
primitive neuroectodermal tumor 18 | 3,035
Kidney cancer 16 | 2,613
Pick disease 15 | 1,894
adult high grade glioma 15 | 3,801
astrocytic glioma 15 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
Waldenstrons macroglobulinemia 14 | 765
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
Multiple myeloma 13 | 1,332
acute quadriplegic myopathy 13 | 1,158
invasive ductal carcinoma 13 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
subependymal giant cell astrocytoma 12 | 2,287
colon cancer 11 | 1,478
Astrocytoma, Pilocytic 10 | 3,081
Rheumatoid arthritis 9 | 1,191
tuberculosis 9 | 2,010
juvenile dermatomyositis 8 | 1,187
lung adenocarcinoma 8 | 2,716
pancreatic cancer 8 | 2,398
astrocytoma 7 | 1,146
nasopharyngeal carcinoma 7 | 1,058
pediatric high grade glioma 7 | 1,064
Autosomal recessive predisposition 6 | 1,442
HIV Infections 6 | 102
group 4 medulloblastoma 6 | 1,855
spina bifida 6 | 1,074
Amyotrophic lateral sclerosis 5 | 451
Atopic dermatitis 5 | 952
Intellectual disability 5 | 1,016
adrenocortical carcinoma 5 | 1,428
aldosterone-producing adenoma 5 | 665
breast carcinoma 5 | 1,638
hepatocellular carcinoma 5 | 547
interstitial cystitis 5 | 2,312
primary pancreatic ductal adenocarcinoma 5 | 1,109
progressive supranuclear palsy 5 | 676
ulcerative colitis 5 | 1,819
Alzheimer's disease 4 | 658
Hypoplastic mandible condyle 4 | 275
Liver Cirrhosis, Experimental 4 | 769
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Orbital separation excessive 4 | 244
Schizophrenia 4 | 1,160
acute myeloid leukemia 4 | 783
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
hereditary spastic paraplegia 4 | 318
interstitial lung disease 4 | 298
lung carcinoma 4 | 2,843
non primary Sjogren syndrome sicca 4 | 891
tuberculosis and treatment for 6 months 4 | 409
Animal Mammary Neoplasms 3 | 136
Cognitive delay 3 | 608
Congenital hypoplasia of lung 3 | 48
Dull intelligence 3 | 645
Gaucher disease type 1 3 | 180
Global developmental delay 3 | 608
Hyperpigmentation 3 | 37
Influenza 3 | 142
Liver cancer 3 | 604
Low intelligence 3 | 645
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Multiple Sclerosis 3 | 540
Polyhydramnios 3 | 108
Poor school performance 3 | 645
Short stature 3 | 531
Small head 3 | 374
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
inflammatory breast cancer 3 | 286
medulloblastoma 3 | 720
non-small cell lung carcinoma 3 | 317
pituitary cancer 3 | 1,972
sonic hedgehog group medulloblastoma 3 | 467
triple-A syndrome 3 | 17
mucosa-associated lymphoid tissue lymphoma 2 | 484

Tissue

Digestive Tract 91 | 17,369
Female tissues 91 | 17,400
Liver and Pancreas 91 | 16,750
Respiratory system 91 | 16,393
Blood and immune system 90 | 16,909
Cardiovascular System 90 | 15,192
Endocrine System 90 | 18,159
Male tissues 90 | 17,142
Nervous System 90 | 16,725
Skin and soft tissues 90 | 17,230
Urinary Tract 90 | 16,678

Target Family

Non-IDG 77 | 12,091
Enzyme 13 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634
Transporter 1 | 473

Compartment GO Term

Nuclear pore 93 | 93
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Exportin-4 XPO4 Tbio Non-IDG -1.62873 40.7 26
Ran-specific GTPase-activating protein RANBP1 Tbio Enzyme -1.80548 64.8 193
Nuclear pore complex protein Nup50 NUP50 Tbio Non-IDG -1.18445 15.9 270
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.63038 38.8 174
Importin subunit alpha-1 KPNA2 Tbio Non-IDG -1.90187 84.5 281
Importin subunit alpha-5 KPNA1 Tbio Non-IDG -1.95092 85.3 284
ATP-dependent RNA helicase DDX19A DDX19A Tdark Enzyme 0.02 0.99 63
ATP-dependent RNA helicase DDX19B DDX19B Tbio Enzyme -1.25103 10.1 252
Nucleoporin p58/p45 NUP58 Tdark Non-IDG -0.69756 4.39 42
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.72599 482.7 786