Development Level

Tbio 121 | 11,445
Tchem 12 | 1,598
Tclin 4 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 7 | 499
decreased lean body mass 5 | 135
abnormal embryo size 4 | 220
decreased body weight 4 | 161
decreased bone mineral content 4 | 151
abnormal behavior 3 | 298
decreased bone mineral density 3 | 126
decreased total body fat amoun... 3 | 207
increased mean corpuscular hem... 3 | 96
abnormal coat-hair pigmentatio... 2 | 64
decreased body length 2 | 101
decreased heart weight 2 | 27
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular hem... 2 | 31
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
female infertility 2 | 60
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating glycerol... 2 | 9
increased total body fat amoun... 2 | 134
prenatal lethality 2 | 28
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased body length 1 | 32
increased body temperature 1 | 9
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
limb grasping 1 | 41
long tibia 1 | 25
lordosis 1 | 1
male infertility 1 | 123
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
shortened QT interval 1 | 4
small testis 1 | 58
thrombocytopenia 1 | 56
vertebral transformation 1 | 12

Disease

Carcinoma 112 | 11,493
ovarian cancer 93 | 8,520
osteosarcoma 71 | 7,950
medulloblastoma, large-cell 70 | 6,241
glioblastoma 64 | 5,792
lung cancer 62 | 4,740
group 3 medulloblastoma 58 | 4,104
atypical teratoid / rhabdoid tumor 56 | 5,112
psoriasis 55 | 6,694
ependymoma 48 | 4,679
primitive neuroectodermal tumor 45 | 3,035
Cancer 43 | 2,499
Breast cancer 42 | 3,578
adult high grade glioma 39 | 3,801
oligodendroglioma 39 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
malignant mesothelioma 36 | 3,232
Kidney cancer 35 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,291
lung adenocarcinoma 30 | 2,716
Astrocytoma, Pilocytic 29 | 3,081
Multiple myeloma 29 | 1,332
invasive ductal carcinoma 29 | 2,951
non-small cell lung cancer 29 | 2,890
astrocytic glioma 28 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
pancreatic cancer 25 | 2,398
subependymal giant cell astrocytoma 24 | 2,287
dermatomyositis 23 | 966
Pick disease 22 | 1,894
Rheumatoid arthritis 22 | 1,191
Waldenstrons macroglobulinemia 22 | 765
pediatric high grade glioma 22 | 1,064
acute quadriplegic myopathy 20 | 1,158
colon cancer 20 | 1,478
juvenile dermatomyositis 19 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Intellectual disability 17 | 1,016
astrocytoma 17 | 1,146
group 4 medulloblastoma 17 | 1,855
adrenocortical carcinoma 16 | 1,428
diabetes mellitus 16 | 1,728
ductal carcinoma in situ 16 | 1,745
Autosomal recessive predisposition 15 | 1,442
tuberculosis 15 | 2,010
Epilepsy 14 | 792
Short stature 14 | 531
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
breast carcinoma 13 | 1,638
pituitary cancer 13 | 1,972
ulcerative colitis 13 | 1,819
Amyotrophic lateral sclerosis 12 | 451
Atopic dermatitis 12 | 952
acute myeloid leukemia 12 | 783
primary pancreatic ductal adenocarcinoma 12 | 1,109
Emery-Dreifuss muscular dystrophy 11 | 23
Hypoplastic mandible condyle 11 | 275
Mandibular hypoplasia 11 | 275
Micrognathism 11 | 275
Osteoporosis 10 | 363
Progeria 10 | 25
Small head 10 | 374
lung carcinoma 10 | 2,843
progressive supranuclear palsy 10 | 676
Dull intelligence 9 | 645
Fetal Growth Retardation 9 | 189
Infant, Small for Gestational Age 9 | 176
Intrauterine retardation 9 | 176
Leukemia, Myelocytic, Acute 9 | 120
Leukemia, Myeloid, Acute 9 | 105
Liver cancer 9 | 604
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Neurodegenerative disease 9 | 414
Poor school performance 9 | 645
Seizures 9 | 596
cutaneous lupus erythematosus 9 | 1,057
nasopharyngeal carcinoma 9 | 1,058
spina bifida 9 | 1,074
Adenocarcinoma of lung 8 | 142
Alzheimer's disease 8 | 658
Byzanthine arch palate 8 | 194
Cryptorchidism 8 | 296
Failure to gain weight 8 | 365
Pediatric failure to thrive 8 | 365
hepatocellular carcinoma 8 | 547
interstitial cystitis 8 | 2,312
pancreatic carcinoma 8 | 562
Down syndrome 7 | 499
Endometriosis 7 | 540
Muscle hypotonia 7 | 571
Orbital separation excessive 7 | 244
Polycystic ovary syndrome 7 | 360
Prostatic Neoplasms 7 | 495
Schizophrenia 7 | 1,160
aldosterone-producing adenoma 7 | 665
gastric cancer 7 | 459

Tissue

Endocrine System 140 | 18,159
Blood and immune system 137 | 16,909
Digestive Tract 137 | 17,369
Female tissues 137 | 17,400
Liver and Pancreas 137 | 16,750
Male tissues 137 | 17,142
Respiratory system 137 | 16,393
Nervous System 136 | 16,725
Skin and soft tissues 136 | 17,230
Urinary Tract 136 | 16,678
Cardiovascular System 133 | 15,192

Target Family

Non-IDG 101 | 12,091
Transcription Factor 16 | 1,400
Enzyme 13 | 4,145
Epigenetic 5 | 242
Kinase 3 | 634
GPCR 1 | 408
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

Compartment GO Term

Nuclear periphery 141 | 141
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
Teneurin-1 TENM1 Tbio Non-IDG -1.81805 61.8 60
Heterogeneous nuclear ribonucleoprotein M HNRNPM Tbio Non-IDG -1.64443 45.9 331
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Cohesin subunit SA-1 STAG1 Tbio Non-IDG -2.47449 292.2 200
Peptidyl-prolyl cis-trans isomerase G PPIG Tchem Enzyme -3.69407 4421.0 219
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176