Development Level

Tbio 810 | 11,651
Tdark 142 | 6,593
Tchem 124 | 1,388
Tclin 45 | 612

Collection

RFA-RM-18-021 6 | 328
Kinase: IDG Consortium (Target... 5 | 125
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 83 | 979
preweaning lethality, incomple... 39 | 499
embryonic lethality prior to t... 34 | 278
embryonic lethality prior to o... 27 | 239
abnormal embryo size 24 | 220
increased lean body mass 16 | 172
increased total body fat amoun... 16 | 134
decreased lean body mass 15 | 135
decreased total body fat amoun... 15 | 207
decreased bone mineral content 14 | 151
embryonic growth retardation 13 | 106
increased startle reflex 13 | 112
abnormal behavior 12 | 298
abnormal bone structure 11 | 187
decreased vertical activity 10 | 208
decreased circulating glucose ... 9 | 126
enlarged heart 9 | 210
hyperactivity 9 | 148
decreased blood urea nitrogen ... 8 | 51
hypoactivity 8 | 132
increased bone mineral content 8 | 108
increased circulating alkaline... 8 | 122
abnormal gait 7 | 69
abnormal retina morphology 7 | 71
decreased body weight 7 | 161
decreased bone mineral density 7 | 126
decreased circulating HDL chol... 7 | 68
decreased circulating choleste... 7 | 93
decreased circulating triglyce... 7 | 79
decreased mean corpuscular vol... 7 | 79
increased mean corpuscular hem... 7 | 96
increased mean corpuscular vol... 7 | 92
increased or absent threshold ... 7 | 101
thrombocytopenia 7 | 56
abnormal lens morphology 6 | 81
abnormal neural tube closure 6 | 46
abnormal seminal vesicle morph... 6 | 114
abnormal testis morphology 6 | 43
cataract 6 | 92
decreased circulating insulin ... 6 | 76
decreased circulating serum al... 6 | 82
decreased fasted circulating g... 6 | 65
decreased hemoglobin content 6 | 68
decreased prepulse inhibition 6 | 82
increased leukocyte cell numbe... 6 | 47
increased prepulse inhibition 6 | 32
abnormal heart morphology 5 | 162
abnormal sleep behavior 5 | 70
decreased circulating alanine ... 5 | 47
decreased circulating alkaline... 5 | 46
decreased grip strength 5 | 116
decreased lymphocyte cell numb... 5 | 83
improved glucose tolerance 5 | 79
increased bone mineral density 5 | 72
increased circulating sodium l... 5 | 71
increased grip strength 5 | 41
increased red blood cell distr... 5 | 34
limb grasping 5 | 41
pallor 5 | 34
small testis 5 | 58
abnormal epididymis morphology 4 | 42
abnormal joint morphology 4 | 23
abnormal kidney morphology 4 | 65
abnormal pericardium morpholog... 4 | 26
abnormal vibrissa morphology 4 | 25
decreased body length 4 | 101
decreased circulating LDL chol... 4 | 38
decreased circulating phosphat... 4 | 27
decreased erythrocyte cell num... 4 | 62
decreased heart weight 4 | 27
decreased mean corpuscular hem... 4 | 50
decreased red blood cell distr... 4 | 41
edema 4 | 59
enlarged epididymis 4 | 31
impaired glucose tolerance 4 | 75
increased blood urea nitrogen ... 4 | 48
increased circulating HDL chol... 4 | 80
increased circulating choleste... 4 | 66
increased circulating creatini... 4 | 38
increased fasted circulating g... 4 | 76
increased mean platelet volume 4 | 45
increased monocyte cell number 4 | 63
increased neutrophil cell numb... 4 | 46
male infertility 4 | 123
prenatal lethality prior to he... 4 | 87
syndactyly 4 | 23
vertebral fusion 4 | 23
abnormal coat-hair pigmentatio... 3 | 64
abnormal eye morphology 3 | 68
abnormal limb bud morphology 3 | 17
decreased circulating creatini... 3 | 39
decreased hematocrit 3 | 46
impaired pupillary reflex 3 | 26
increased anti-nuclear antigen... 3 | 19
increased circulating amylase ... 3 | 25
increased circulating calcium ... 3 | 34
increased circulating chloride... 3 | 41
increased circulating potassiu... 3 | 29
increased circulating total pr... 3 | 28
pale yolk sac 3 | 25

Disease

Carcinoma 681 | 11,493
ovarian cancer 594 | 8,520
osteosarcoma 509 | 7,950
psoriasis 435 | 6,694
glioblastoma 394 | 5,792
medulloblastoma, large-cell 379 | 6,241
atypical teratoid / rhabdoid tumor 319 | 5,112
lung cancer 303 | 4,740
ependymoma 284 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 240 | 3,291
Breast cancer 228 | 3,578
adult high grade glioma 227 | 3,801
Astrocytoma, Pilocytic 225 | 3,081
group 3 medulloblastoma 218 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 213 | 1,962
Cancer 208 | 2,499
invasive ductal carcinoma 208 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 188 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 187 | 2,989
malignant mesothelioma 187 | 3,232
diabetes mellitus 186 | 1,728
lung carcinoma 175 | 2,843
non-small cell lung cancer 175 | 2,890
tuberculosis 173 | 2,010
lung adenocarcinoma 171 | 2,716
pancreatic cancer 168 | 2,398
oligodendroglioma 163 | 2,850
primitive neuroectodermal tumor 150 | 3,035
subependymal giant cell astrocytoma 150 | 2,287
interstitial cystitis 146 | 2,312
astrocytic glioma 142 | 2,597
Pick disease 140 | 1,894
Multiple myeloma 139 | 1,332
Autosomal recessive predisposition 134 | 1,442
pituitary cancer 134 | 1,972
group 4 medulloblastoma 129 | 1,855
Kidney cancer 127 | 2,613
Rheumatoid arthritis 121 | 1,191
ductal carcinoma in situ 117 | 1,745
cystic fibrosis 115 | 1,696
breast carcinoma 113 | 1,638
active Crohn's disease 112 | 922
ulcerative colitis 109 | 1,819
astrocytoma 104 | 1,146
dermatomyositis 94 | 966
adrenocortical carcinoma 91 | 1,428
juvenile dermatomyositis 91 | 1,187
acute quadriplegic myopathy 87 | 1,158
Schizophrenia 84 | 1,160
Epilepsy 82 | 792
pediatric high grade glioma 82 | 1,064
Ankylosing spondylitis 80 | 140
Arthritis 76 | 290
Intellectual disability 76 | 1,016
colon cancer 75 | 1,478
Behcet's disease 73 | 89
Hypersensitivity reaction type II disease 73 | 253
active ulcerative colitis 71 | 764
primary pancreatic ductal adenocarcinoma 68 | 1,109
Alzheimer's disease 67 | 658
esophageal adenocarcinoma 67 | 737
non primary Sjogren syndrome sicca 67 | 891
cutaneous lupus erythematosus 66 | 1,057
Acquired immunodeficiency syndrome 64 | 197
Juvenile rheumatoid arthritis 64 | 111
spina bifida 61 | 1,074
Prostatic Neoplasms 60 | 495
Uveitis 58 | 103
Obesity 57 | 678
Seizures 57 | 596
Herpes zoster 56 | 68
Human immunodeficiency virus infectious disease 56 | 138
Liver Cirrhosis, Experimental 56 | 769
Muscle hypotonia 56 | 571
Stevens-Johnson syndrome 56 | 92
Psoriatic arthritis 55 | 86
Atopic dermatitis 54 | 952
Neurodegenerative disease 53 | 414
Liver disease 52 | 237
Dull intelligence 51 | 645
Low intelligence 51 | 645
Mental Retardation 51 | 645
Mental deficiency 51 | 645
Multiple Sclerosis 51 | 540
Poor school performance 51 | 645
progressive supranuclear palsy 51 | 676
Anemia 50 | 365
Cognitive delay 50 | 608
Global developmental delay 50 | 608
Mental and motor retardation 50 | 608
pancreatic carcinoma 50 | 562
acute myeloid leukemia 49 | 783
nasopharyngeal carcinoma 49 | 1,058
Down syndrome 48 | 499
Waldenstrons macroglobulinemia 48 | 765
aldosterone-producing adenoma 48 | 665
Kidney disease 47 | 430
primary Sjogren syndrome 47 | 735
Bipolar Disorder 45 | 666
Hypertension 45 | 396

Tissue

Endocrine System 1,018 | 18,159
Digestive Tract 1,015 | 17,369
Female tissues 1,010 | 17,400
Skin and soft tissues 1,010 | 17,230
Liver and Pancreas 1,004 | 16,750
Male tissues 1,002 | 17,142
Urinary Tract 993 | 16,678
Blood and immune system 992 | 16,909
Nervous System 979 | 16,725
Respiratory system 973 | 16,393
Cardiovascular System 925 | 15,192

Target Family

Non-IDG 578 | 12,091
Enzyme 424 | 4,145
Transporter 39 | 473
Kinase 28 | 634
Ion Channel 23 | 344
Transcription Factor 21 | 1,400
GPCR 6 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Nuclear outer membrane-endopla... 1,121 | 1,121
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Sphingomyelin phosphodiesterase 4 SMPD4 Tbio Enzyme -0.89678 7.05 66
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Tyrosine-protein phosphatase non-receptor type 5 PTPN5 Tchem Enzyme -1.85420 70.8 225
Probable ergosterol biosynthetic protein 28 ERG28 Tdark Non-IDG -1.25331 16.7 40
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388