Development Level

Tbio 17 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased vertical activity 2 | 208
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating lipase l... 1 | 3
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
edema 1 | 59
hemorrhage 1 | 23
hypoactivity 1 | 132
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
thrombocytopenia 1 | 56

Disease

Carcinoma 17 | 11,493
ovarian cancer 14 | 8,520
psoriasis 12 | 6,694
ependymoma 8 | 4,679
invasive ductal carcinoma 8 | 2,951
subependymal giant cell astrocytoma 8 | 2,287
Autosomal recessive predisposition 7 | 1,442
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Muscle hypotonia 5 | 571
atypical teratoid / rhabdoid tumor 5 | 5,112
breast carcinoma 5 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
Childhood onset 4 | 38
Kidney cancer 4 | 2,613
Liver cancer 4 | 604
Seizures 4 | 596
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Cataract 3 | 297
Cognitive delay 3 | 608
Creatine phosphokinase serum increased 3 | 110
Dysarthria 3 | 192
Elevated creatine kinase 3 | 110
Emery-Dreifuss muscular dystrophy 3 | 23
Epilepsy 3 | 792
Global developmental delay 3 | 608
Lens Opacities 3 | 231
Mental and motor retardation 3 | 608
Muscular Dystrophy, Emery-Dreifuss 3 | 5
Muscular dystrophy 3 | 75
Neurodegenerative disease 3 | 414
Nystagmus 3 | 317
Pick disease 3 | 1,894
Slow progression 3 | 89
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
aldosterone-producing adenoma 3 | 665
colon cancer 3 | 1,478
progressive supranuclear palsy 3 | 676
ulcerative colitis 3 | 1,819
Adult onset 2 | 82
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Anteverted nostril 2 | 191
Asthma 2 | 385
Autistic Disorder 2 | 364
Babinski Reflex 2 | 100
Broad flat nasal bridge 2 | 236
Cerebral atrophy 2 | 178
Down syndrome 2 | 499
Electromyogram abnormal 2 | 49
Failure to gain weight 2 | 365
Gliosis 2 | 56
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Large intestine cancer 2 | 126
Melanoma 2 | 711
Multiple myeloma 2 | 1,332
Muscle Hypertonia 2 | 88
Muscle biopsy shows dystrophic changes 2 | 39
Nasal bridge wide 2 | 236
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Physical aggression 2 | 76
Polyhydramnios 2 | 108
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Reduced fetal movement 2 | 51
Schizophrenia 2 | 1,160
Strabismus 2 | 270
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010

Tissue

Endocrine System 25 | 18,159
Digestive Tract 24 | 17,369
Female tissues 24 | 17,400
Urinary Tract 24 | 16,678
Blood and immune system 23 | 16,909
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Skin and soft tissues 23 | 17,230
Respiratory system 21 | 16,393
Cardiovascular System 20 | 15,192
Nervous System 20 | 16,725

Target Family

Non-IDG 14 | 12,091
Enzyme 7 | 4,145
Kinase 3 | 634
GPCR 1 | 408
Ion Channel 1 | 344

Compartment GO Term

Nuclear outer membrane 26 | 26
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Cytosolic phospholipase A2 delta PLA2G4D Tbio Enzyme -0.54284 3.41 45
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
Sigma non-opioid intracellular receptor 1 SIGMAR1 Tclin Non-IDG -2.28907 210.0 143
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
UDP-glucuronosyltransferase 2B28 UGT2B28 Tbio Enzyme -0.88835 8.45 45
Nesprin-3 SYNE3 Tbio Non-IDG -0.90535 8.77 107
Bcl-2-related ovarian killer protein BOK Tbio Non-IDG -1.64193 42.6 207
Myotonin-protein kinase DMPK Tchem Kinase -2.70945 496.6 196
Transmembrane protein 109 TMEM109 Tbio Non-IDG -0.59060 3.93 38