Development Level

Tbio 9 | 11,651

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased caudal vertebrae num... 1 | 53
decreased circulating glucose ... 1 | 126
embryonic lethality prior to o... 1 | 239
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 8 | 11,493
lung cancer 6 | 4,740
psoriasis 6 | 6,694
Meier-Gorlin syndrome 5 | 10
group 3 medulloblastoma 5 | 4,104
ovarian cancer 5 | 8,520
Autosomal recessive predisposition 4 | 1,442
Birth length less than 3rd percentile 4 | 6
Congenital small ears 4 | 48
Delayed bone age 4 | 136
EAR, PATELLA, SHORT STATURE SYNDROME 4 | 7
Failure to gain weight 4 | 365
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Isolated growth hormone deficiency 4 | 30
Pediatric failure to thrive 4 | 365
Seckel syndrome 4 | 34
Slender, gracile long tubular bones 4 | 21
Small head 4 | 374
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
Congenital hypoplasia of breast 3 | 25
Cryptorchidism 3 | 296
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Feeding difficulties 3 | 127
Gastroesophageal reflux disease 3 | 110
Heartburn 3 | 78
Hypertrophy of clitoris 3 | 40
Hypoplasia of the maxilla 3 | 66
Hypoplastic mandible condyle 3 | 275
Hypotrophic maxilla 3 | 66
Mandibular hypoplasia 3 | 275
Maxillary retrognathia 3 | 66
Microcephaly 3 | 166
Micrognathism 3 | 275
Microstomia 3 | 78
Retrusion of upper jaw bones 3 | 66
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
malignant mesothelioma 3 | 3,232
Absent bone maturation in sternum 2 | 4
Absent sternal ossification 2 | 4
Breast cancer 2 | 3,578
Congenital hypoplasia of penis 2 | 176
Full lower lip 2 | 64
Genu varum 2 | 29
Low set ears 2 | 181
Patella aplasia-hypoplasia 2 | 12
Prominent lower lip 2 | 64
Pulmonary emphysema 2 | 48
Short ribs 2 | 30
Small labia majora 2 | 16
Triangular face 2 | 58
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
pediatric high grade glioma 2 | 1,064
Abnormality of pelvic girdle bone morphology 1 | 37
Blepharophimosis 1 | 70
Congenital Camptodactyly 1 | 40
Congenital clubfoot 1 | 109
Congenital deafness 1 | 185
Congenital hemivertebra 1 | 25
Contracture of joint of hand 1 | 30
Deafness 1 | 198
DiGeorge syndrome 1 | 47
Dwarfism 1 | 37
Dyspnea 1 | 76
Frontal bossing 1 | 157
Gout 1 | 104
Hearing Loss, Partial 1 | 185
Infectious disease of lung 1 | 29
Knee joint valgus deformity 1 | 56
Long eyelashes 1 | 37
Long narrow head 1 | 75
Low Birth Weights 1 | 69
Microretrognathia 1 | 13
Multiple pulmonary infections 1 | 29
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Narrow thorax 1 | 53
Neuronal ceroid lipofuscinosis 1 | 28
No development of motor milestones 1 | 147
Overcurvature of nail 1 | 6
Patellar aplasia 1 | 8
Range of joint movement increased 1 | 32
Recurrent pneumonia 1 | 29
Recurrent pulmonary infections 1 | 29
Respiratory distress 1 | 43
Short palpebral fissure 1 | 38
Small for gestational age (disorder) 1 | 69
Thin rib 1 | 21
Thin skin 1 | 47
Tracheomalacia 1 | 22
Turridolichocephaly 1 | 75
hearing impairment 1 | 199

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 8 | 12,091
Transcription Factor 1 | 1,400

Compartment GO Term

Nuclear origin of replication ... 9 | 9
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Origin recognition complex subunit 6 ORC6 Tbio Non-IDG -1.38268 26.3 165
Cell division control protein 6 homolog CDC6 Tbio Non-IDG -2.51683 336.8 574
Replication initiator 1 REPIN1 Tbio Transcription Factor -1.58043 35.7 46
Origin recognition complex subunit 4 ORC4 Tbio Non-IDG -1.52127 33.7 155
Origin recognition complex subunit 2 ORC2 Tbio Non-IDG -0.68275 4.92 168
Origin recognition complex subunit 1 ORC1 Tbio Non-IDG -1.42573 28.0 148
Origin recognition complex subunit 5 ORC5 Tbio Non-IDG -1.50983 31.3 71
Leucine-rich repeat and WD repeat-containing protein 1 LRWD1 Tbio Non-IDG -1.08139 12.9 65
Origin recognition complex subunit 3 ORC3 Tbio Non-IDG -1.25409 17.4 192