Development Level

Tbio 188 | 10,625
Tdark 55 | 7,003
Tchem 29 | 1,890
Tclin 12 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 10 | 633
abnormal behavior 5 | 226
decreased bone mineral content 5 | 157
increased mean corpuscular hem... 5 | 93
preweaning lethality, incomple... 5 | 260
abnormal bone structure 4 | 131
decreased body weight 4 | 174
decreased grip strength 4 | 123
decreased lean body mass 4 | 195
increased circulating alkaline... 4 | 119
abnormal sleep behavior 3 | 63
abnormal snout morphology 3 | 18
decreased circulating HDL chol... 3 | 77
decreased circulating alkaline... 3 | 41
decreased circulating choleste... 3 | 85
decreased rib number 3 | 59
hypoactivity 3 | 89
impaired glucose tolerance 3 | 52
increased lean body mass 3 | 107
small thymus 3 | 11
tremors 3 | 34
abnormal behavioral response t... 2 | 52
abnormal heart left ventricle ... 2 | 20
abnormal lens morphology 2 | 73
abnormal locomotor activation 2 | 26
abnormal motor coordination/ b... 2 | 4
abnormal retina morphology 2 | 100
decreased basophil cell number 2 | 11
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 121
decreased circulating glycerol... 2 | 19
decreased fasted circulating g... 2 | 49
decreased hematocrit 2 | 25
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased pulmonary respirator... 2 | 4
enlarged heart 2 | 111
enlarged stomach 2 | 2
hydrops fetalis 2 | 22
hyperactivity 2 | 108
immune system phenotype 2 | 17
increased or absent threshold ... 2 | 128
lethargy 2 | 5
short tibia 2 | 82
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal limb bud morphology 1 | 15
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal tail morphology 1 | 17
abnormal tooth morphology 1 | 24
cataract 1 | 26
corneal opacity 1 | 25
cyanosis 1 | 6
decreased B cell number 1 | 30
decreased body length 1 | 108
decreased circulating calcium ... 1 | 33
decreased circulating magnesiu... 1 | 11
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased thoracic vertebrae n... 1 | 7
decreased vertical activity 1 | 22
edema 1 | 11
enlarged thymus 1 | 4
female infertility 1 | 34
hemorrhage 1 | 12
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating choleste... 1 | 53
increased circulating creatine... 1 | 2
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
microphthalmia 1 | 15
narrow eye opening 1 | 15
prolonged PQ interval 1 | 3
respiratory system phenotype 1 | 2
shortened PQ interval 1 | 6
thrombocytopenia 1 | 46

Disease

ovarian cancer 164 | 8,484
osteosarcoma 146 | 7,933
medulloblastoma, large-cell 114 | 6,234
psoriasis 104 | 6,685
lung cancer 101 | 4,466
glioblastoma 98 | 5,572
atypical teratoid / rhabdoid tumor 72 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 61 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 60 | 2,988
malignant mesothelioma 60 | 3,162
Breast cancer 58 | 3,094
non-small cell lung cancer 58 | 2,798
group 3 medulloblastoma 55 | 2,254
pediatric high grade glioma 54 | 2,712
invasive ductal carcinoma 53 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 49 | 2,956
oligodendroglioma 47 | 2,849
lung adenocarcinoma 46 | 2,713
primitive neuroectodermal tumor 46 | 3,031
Cancer 44 | 2,346
ependymoma 44 | 2,514
pancreatic cancer 43 | 2,300
Multiple myeloma 42 | 1,327
pilocytic astrocytoma 42 | 3,086
Carcinoma 40 | 2,147
subependymal giant cell astrocytoma 40 | 2,287
lung carcinoma 38 | 2,844
Pick disease 36 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,795
acute quadriplegic myopathy 34 | 1,157
group 4 medulloblastoma 34 | 1,875
interstitial cystitis 34 | 2,299
colon cancer 33 | 1,475
ulcerative colitis 33 | 2,087
breast carcinoma 32 | 1,614
dermatomyositis 32 | 933
adult high grade glioma 31 | 2,148
ductal carcinoma in situ 31 | 1,745
primary pancreatic ductal adenocarcinoma 31 | 1,271
astrocytic glioma 28 | 2,241
juvenile dermatomyositis 28 | 1,189
tuberculosis 27 | 1,557
Rheumatoid Arthritis 26 | 1,160
astrocytoma 26 | 1,493
cystic fibrosis 26 | 1,665
adrenocortical carcinoma 25 | 1,427
pituitary cancer 25 | 1,972
atypical teratoid/rhabdoid tumor 23 | 1,095
medulloblastoma 23 | 1,524
posterior fossa group A ependymoma 23 | 1,511
primary Sjogren syndrome 23 | 789
nasopharyngeal carcinoma 22 | 1,056
Waldenstrons macroglobulinemia 21 | 765
cutaneous lupus erythematosus 21 | 1,056
sonic hedgehog group medulloblastoma 20 | 1,482
aldosterone-producing adenoma 18 | 664
diabetes mellitus 18 | 1,663
tuberculosis and treatment for 6 months 17 | 686
Atopic dermatitis 16 | 944
Alzheimer's disease 15 | 644
Amyotrophic Lateral Sclerosis 15 | 431
Down syndrome 15 | 548
Duchenne muscular dystrophy 15 | 602
Emery-Dreifuss muscular dystrophy 15 | 24
esophageal adenocarcinoma 15 | 737
non primary Sjogren syndrome sicca 15 | 840
Mammary Neoplasms 14 | 410
Neurodegenerative disease 13 | 383
gastric carcinoma 13 | 832
posterior fossa group B ependymoma 13 | 1,530
progressive supranuclear palsy 13 | 674
Asthma 12 | 349
active Crohn's disease 12 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 499
spina bifida 12 | 1,064
Epilepsy 11 | 346
active ulcerative colitis 11 | 477
acute myeloid leukemia 11 | 780
hereditary spastic paraplegia 11 | 313
mucosa-associated lymphoid tissue lymphoma 11 | 480
Endometriosis 10 | 535
sarcoidosis 10 | 358
IGA Glomerulonephritis 9 | 454
Multiple Sclerosis 9 | 498
Progeria 9 | 22
Prostatic Neoplasms 9 | 471
Schizophrenia 9 | 501
Vascular disease 9 | 281
pancreatic carcinoma 9 | 567
Bipolar Disorder 8 | 266
Cardiomyopathy 8 | 110
Chronic Lymphocytic Leukemia 8 | 242
Diabetes Mellitus, Non-Insulin-Dependent 8 | 157
Parkinson's disease 8 | 364
tuberculosis and treatment for 3 months 8 | 327
Influenza 7 | 142
Intellectual disability 7 | 573
hepatocellular carcinoma 7 | 532
urothelial carcinoma 7 | 318
Crohn's disease 6 | 304

Tissue

Endocrine System 279 | 18,512
Nervous System 279 | 18,561
Blood and immune system 278 | 17,995
Digestive Tract 278 | 18,473
Female tissues 278 | 18,647
Liver and Pancreas 277 | 18,136
Male tissues 277 | 17,969
Urinary Tract 277 | 18,444
Skin and soft tissues 276 | 18,115
Cardiovascular System 275 | 17,958
Respiratory system 274 | 17,484

Target Family

Non-IDG 172 | 11,971
Enzyme 53 | 4,146
Transcription Factor 17 | 1,400
Ion Channel 14 | 341
Kinase 11 | 634
Transporter 6 | 473
Epigenetic 5 | 242
GPCR 5 | 406
Nuclear Receptor 1 | 48

Compartment GO Term

Nuclear membrane 284 | 284
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Testis-specific gene 10 protein TSGA10 Tbio Non-IDG -1.05563 13.1 82
Nucleolar GTP-binding protein 1 GTPBP4 Tbio Non-IDG -3.21425 1443.3 95
Transmembrane channel-like protein 8 TMC8 Tbio Ion Channel -1.45295 32.2 147
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Ceramide synthase 3 CERS3 Tbio Transcription Factor -0.90774 9.32 99
Pre-mRNA-splicing factor 38A PRPF38A Tdark Non-IDG -0.69167 4.80 72
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
39S ribosomal protein L19, mitochondrial MRPL19 Tbio Non-IDG -0.91149 8.14 108
Protein ELYS AHCTF1 Tbio Non-IDG -1.30356 22.8 57