Development Level

Tbio 271 | 10,625
Tdark 123 | 7,003
Tchem 46 | 1,890
Tclin 16 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 2 | 24
GPCR: IDG Consortium (Targets) 2 | 128
Ion Channel: IDG Consortium (Targets) 2 | 102
Kinase: IDG Consortium (Complete/Control) 2 | 37

IMPC Phenotype

preweaning lethality, complete... 15 | 633
abnormal behavior 8 | 226
preweaning lethality, incomple... 8 | 260
decreased bone mineral content 7 | 157
abnormal bone structure 6 | 131
decreased body weight 6 | 174
decreased grip strength 6 | 123
abnormal retina morphology 5 | 100
decreased lean body mass 5 | 195
increased circulating alkaline... 5 | 119
increased mean corpuscular hem... 5 | 93
abnormal sleep behavior 4 | 63
decreased circulating glucose ... 4 | 121
decreased rib number 4 | 59
enlarged heart 4 | 111
hypoactivity 4 | 89
increased lean body mass 4 | 107
tremors 4 | 34
abnormal behavioral response t... 3 | 52
abnormal heart left ventricle ... 3 | 20
abnormal snout morphology 3 | 18
decreased circulating HDL chol... 3 | 77
decreased circulating alkaline... 3 | 41
decreased circulating choleste... 3 | 85
decreased circulating insulin ... 3 | 75
decreased fasted circulating g... 3 | 49
decreased hematocrit 3 | 25
decreased hemoglobin content 3 | 53
hyperactivity 3 | 108
impaired glucose tolerance 3 | 52
increased hematocrit 3 | 36
short tibia 3 | 82
small thymus 3 | 11
abnormal QRS complex 2 | 25
abnormal bone mineralization 2 | 55
abnormal eye morphology 2 | 38
abnormal heart morphology 2 | 51
abnormal lens morphology 2 | 73
abnormal locomotor activation 2 | 26
abnormal motor coordination- b... 2 | 4
abnormal retinal pigmentation 2 | 61
decreased basophil cell number 2 | 11
decreased bone mineral density 2 | 126
decreased circulating calcium ... 2 | 33
decreased circulating glycerol... 2 | 19
decreased leukocyte cell numbe... 2 | 54
decreased pulmonary respirator... 2 | 4
embryonic lethality prior to o... 2 | 148
enlarged stomach 2 | 2
hydrops fetalis 2 | 22
immune system phenotype 2 | 17
impaired righting response 2 | 19
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 37
increased or absent threshold ... 2 | 128
lethargy 2 | 5
male infertility 2 | 62
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal head morphology 1 | 10
abnormal iris morphology 1 | 12
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal skin morphology 1 | 23
abnormal tooth morphology 1 | 24
cataract 1 | 26
corneal opacity 1 | 25
decreased body length 1 | 108
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased thoracic vertebrae n... 1 | 7
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
enlarged heart atrium 1 | 2
female infertility 1 | 34
hemorrhage 1 | 12
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
microphthalmia 1 | 15
shortened PQ interval 1 | 6
sparse hair 1 | 6
thrombocytopenia 1 | 46

Disease

ovarian cancer 246 | 8,491
osteosarcoma 227 | 7,933
medulloblastoma, large-cell 175 | 6,234
psoriasis 166 | 6,685
glioblastoma 149 | 5,572
lung cancer 141 | 4,473
atypical teratoid / rhabdoid tumor 113 | 4,369
malignant mesothelioma 102 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 96 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 89 | 2,988
group 3 medulloblastoma 82 | 2,254
invasive ductal carcinoma 81 | 2,950
non-small cell lung cancer 80 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 78 | 2,956
oligodendroglioma 78 | 2,849
pediatric high grade glioma 77 | 2,712
primitive neuroectodermal tumor 76 | 3,031
Breast cancer 73 | 3,098
pilocytic astrocytoma 70 | 3,086
lung adenocarcinoma 68 | 2,714
ependymoma 66 | 2,514
pancreatic cancer 66 | 2,300
Carcinoma 65 | 2,147
subependymal giant cell astrocytoma 64 | 2,287
lung carcinoma 63 | 2,844
interstitial cystitis 59 | 2,299
Cancer 57 | 2,346
group 4 medulloblastoma 56 | 1,875
Multiple myeloma 55 | 1,327
Pick disease 53 | 1,893
ulcerative colitis 53 | 2,087
pancreatic ductal adenocarcinoma liver metastasis 52 | 1,795
breast carcinoma 49 | 1,614
adult high grade glioma 48 | 2,148
ductal carcinoma in situ 47 | 1,745
astrocytic glioma 46 | 2,241
cystic fibrosis 46 | 1,670
acute quadriplegic myopathy 45 | 1,157
astrocytoma 44 | 1,493
dermatomyositis 44 | 966
primary pancreatic ductal adenocarcinoma 43 | 1,271
colon cancer 41 | 1,475
pituitary cancer 41 | 1,972
tuberculosis 41 | 1,563
adrenocortical carcinoma 40 | 1,427
sonic hedgehog group medulloblastoma 39 | 1,482
Rheumatoid Arthritis 38 | 1,170
atypical teratoid/rhabdoid tumor 37 | 1,095
juvenile dermatomyositis 36 | 1,189
posterior fossa group A ependymoma 36 | 1,511
medulloblastoma 35 | 1,524
posterior fossa group B ependymoma 32 | 1,530
nasopharyngeal carcinoma 29 | 1,056
primary Sjogren syndrome 29 | 788
Waldenstrons macroglobulinemia 28 | 764
diabetes mellitus 28 | 1,663
cutaneous lupus erythematosus 27 | 1,056
progressive supranuclear palsy 26 | 674
tuberculosis and treatment for 6 months 25 | 686
Atopic dermatitis 23 | 944
non primary Sjogren syndrome sicca 23 | 840
Alzheimer's disease 22 | 644
aldosterone-producing adenoma 21 | 664
Amyotrophic Lateral Sclerosis 20 | 432
Down syndrome 20 | 548
active Crohn's disease 20 | 918
gastric carcinoma 20 | 832
acute myeloid leukemia 19 | 785
Duchenne muscular dystrophy 18 | 602
Neurodegenerative disease 18 | 383
esophageal adenocarcinoma 18 | 737
active ulcerative colitis 17 | 477
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 499
spina bifida 17 | 1,064
Endometriosis 16 | 535
pancreatic carcinoma 16 | 567
Asthma 15 | 349
Emery-Dreifuss muscular dystrophy 15 | 24
Mammary Neoplasms 15 | 410
sarcoidosis 15 | 368
Epilepsy 14 | 346
Parkinson's disease 14 | 364
hereditary spastic paraplegia 13 | 313
mucosa-associated lymphoid tissue lymphoma 13 | 480
Crohn's disease 12 | 304
IGA Glomerulonephritis 12 | 454
Prostatic Neoplasms 12 | 471
Intellectual disability 11 | 573
Multiple Sclerosis 11 | 498
Schizophrenia 11 | 503
chronic lymphocytic leukemia 11 | 244
fibroadenoma 11 | 557
Bipolar Disorder 10 | 266
Vascular disease 10 | 281
hepatocellular carcinoma 10 | 550
urothelial carcinoma 10 | 318
Cardiomyopathy 9 | 110
Kidney disease 9 | 397
gastric cancer 9 | 436
inflammatory breast cancer 9 | 404

Tissue

Nervous System 450 | 18,560
Female tissues 449 | 18,646
Blood and immune system 448 | 17,994
Endocrine System 448 | 18,511
Digestive Tract 447 | 18,472
Male tissues 447 | 17,968
Urinary Tract 447 | 18,443
Liver and Pancreas 445 | 18,135
Skin and soft tissues 444 | 18,114
Cardiovascular System 443 | 17,957
Respiratory system 441 | 17,483

Target Family

Non-IDG 270 | 11,969
Enzyme 90 | 4,146
Transcription Factor 39 | 1,400
Ion Channel 18 | 341
Kinase 16 | 634
GPCR 8 | 408
Epigenetic 7 | 242
Transporter 7 | 473
Nuclear Receptor 1 | 48

Compartment GO Term

Nuclear membrane 456 | 456
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
[Protein ADP-ribosylarginine] hydrolase ADPRH Tbio Enzyme -0.88930 6.69 100
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Putative nuclear envelope pore membrane protein POM 121B POM121B Tdark Non-IDG 0.00000 0
Aquaporin-1 AQP1 Tbio Non-IDG -3.06090 1040.5 321
Protein FAM181B FAM181B Tdark Non-IDG 0.30 0.63 19
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.78255 613.4 202
Zinc finger protein RFP TRIM27 Tbio Non-IDG -1.50884 32.8 154
Adenylate kinase 9 AK9 Tbio Kinase -0.95667 9.15 83
Histone lysine demethylase PHF8 PHF8 Tchem Epigenetic -1.45177 33.5 70
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.75708 61.0 81