Development Level

Tbio 52 | 11,445
Tdark 19 | 6,588
Tchem 10 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased hemoglobin content 3 | 68
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased heart weight 2 | 27
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
enlarged heart 2 | 210
hypoactivity 2 | 132
increased mean corpuscular hem... 2 | 96
increased total body fat amoun... 2 | 134
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal hindlimb morphology 1 | 2
abnormal lens morphology 1 | 81
abnormal limb position 1 | 3
abnormal ovary morphology 1 | 7
abnormal retina morphology 1 | 71
abnormal thymus morphology 1 | 7
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating lipase l... 1 | 3
decreased circulating magnesiu... 1 | 13
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
enlarged thymus 1 | 5
female infertility 1 | 60
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
male infertility 1 | 123
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 52 | 11,493
osteosarcoma 39 | 7,950
ovarian cancer 39 | 8,520
psoriasis 33 | 6,694
glioblastoma 29 | 5,792
medulloblastoma, large-cell 29 | 6,241
lung cancer 28 | 4,740
atypical teratoid / rhabdoid tumor 25 | 5,112
ependymoma 22 | 4,679
Breast cancer 20 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
group 3 medulloblastoma 19 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
malignant mesothelioma 18 | 3,232
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
non-small cell lung cancer 16 | 2,890
oligodendroglioma 16 | 2,850
pancreatic cancer 16 | 2,398
Astrocytoma, Pilocytic 14 | 3,081
Emery-Dreifuss muscular dystrophy 14 | 23
interstitial cystitis 14 | 2,312
lung adenocarcinoma 13 | 2,716
lung carcinoma 13 | 2,843
tuberculosis 13 | 2,010
Autosomal recessive predisposition 12 | 1,442
Cancer 12 | 2,499
Multiple myeloma 12 | 1,332
astrocytic glioma 12 | 2,597
invasive ductal carcinoma 12 | 2,951
Kidney cancer 11 | 2,613
acute quadriplegic myopathy 11 | 1,158
colon cancer 11 | 1,478
primitive neuroectodermal tumor 11 | 3,035
subependymal giant cell astrocytoma 11 | 2,287
Progeria 10 | 25
ductal carcinoma in situ 10 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
primary pancreatic ductal adenocarcinoma 10 | 1,109
Rheumatoid arthritis 9 | 1,191
Waldenstrons macroglobulinemia 9 | 765
Atopic dermatitis 8 | 952
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Pick disease 8 | 1,894
adrenocortical carcinoma 8 | 1,428
dermatomyositis 8 | 966
group 4 medulloblastoma 8 | 1,855
juvenile dermatomyositis 8 | 1,187
ulcerative colitis 8 | 1,819
Bipolar Disorder 7 | 666
Orbital separation excessive 7 | 244
Short stature 7 | 531
Vascular disease 7 | 319
cystic fibrosis 7 | 1,696
gastric carcinoma 7 | 807
pediatric high grade glioma 7 | 1,064
primary Sjogren syndrome 7 | 735
Cardiomyopathy 6 | 116
Creatine phosphokinase serum increased 6 | 110
Duchenne muscular dystrophy 6 | 601
Elevated creatine kinase 6 | 110
Failure to gain weight 6 | 365
Infertility 6 | 188
Neurodegenerative disease 6 | 414
Pediatric failure to thrive 6 | 365
aldosterone-producing adenoma 6 | 665
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
nasopharyngeal carcinoma 6 | 1,058
Acquired scoliosis 5 | 281
Chronic Lymphocytic Leukemia 5 | 262
Curvature of spine 5 | 282
Depressive disorder 5 | 409
Epilepsy 5 | 792
Lipodystrophy 5 | 40
Liver cancer 5 | 604
Multiple Sclerosis 5 | 540
Muscular Dystrophy, Emery-Dreifuss 5 | 5
Muscular dystrophy 5 | 75
Pelger-Huet anomaly 5 | 8
acute myeloid leukemia 5 | 783
cutaneous lupus erythematosus 5 | 1,057
mucosa-associated lymphoid tissue lymphoma 5 | 484
pituitary cancer 5 | 1,972
spina bifida 5 | 1,074
Amyotrophic lateral sclerosis 4 | 451
Byzanthine arch palate 4 | 194
Cardiomyopathy, Dilated 4 | 83
Distal muscle weakness 4 | 62
Melanoma 4 | 711
Parkinson's disease 4 | 392
Schizophrenia 4 | 1,160
Skin cancer 4 | 469
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737

Tissue

Endocrine System 81 | 18,159
Liver and Pancreas 81 | 16,750
Male tissues 78 | 17,142
Digestive Tract 77 | 17,369
Female tissues 77 | 17,400
Skin and soft tissues 77 | 17,230
Nervous System 76 | 16,725
Blood and immune system 74 | 16,909
Respiratory system 73 | 16,393
Urinary Tract 73 | 16,678
Cardiovascular System 68 | 15,192

Target Family

Non-IDG 50 | 12,091
Enzyme 13 | 4,145
Ion Channel 11 | 344
Transcription Factor 4 | 1,400
Epigenetic 3 | 242
Transporter 2 | 473
GPCR 1 | 408

Compartment GO Term

Nuclear inner membrane 84 | 84
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Interferon alpha-inducible protein 27, mitochondrial IFI27 Tbio Non-IDG -1.51419 33.3 0
Unconventional prefoldin RPB5 interactor 1 URI1 Tbio Enzyme -2.15409 134.8 150
Neurturin NRTN Tbio Non-IDG -2.21792 170.4 331
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
Nuclear envelope integral membrane protein 2 NEMP2 Tdark Non-IDG 0.43 0.27 3
Inner nuclear membrane protein Man1 LEMD3 Tbio Non-IDG -2.30311 196.6 73
Serine incorporator 3 SERINC3 Tbio Non-IDG -2.44903 264.3 131
Probable C-mannosyltransferase DPY19L3 DPY19L3 Tdark Enzyme -0.34406 1.15 63
Sigma non-opioid intracellular receptor 1 SIGMAR1 Tclin Non-IDG -2.28907 210.0 143