Development Level

Tbio 56 | 11,651
Tdark 19 | 6,593
Tchem 7 | 1,388
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased hemoglobin content 3 | 68
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased heart weight 2 | 27
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
enlarged heart 2 | 210
hypoactivity 2 | 132
increased mean corpuscular hem... 2 | 96
increased total body fat amoun... 2 | 134
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal hindlimb morphology 1 | 2
abnormal lens morphology 1 | 81
abnormal limb position 1 | 3
abnormal ovary morphology 1 | 7
abnormal retina morphology 1 | 71
abnormal thymus morphology 1 | 7
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating lipase l... 1 | 3
decreased circulating magnesiu... 1 | 13
decreased erythrocyte cell num... 1 | 62
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
enlarged thymus 1 | 5
female infertility 1 | 60
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
male infertility 1 | 123
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 52 | 11,493
ovarian cancer 40 | 8,519
osteosarcoma 39 | 7,950
psoriasis 34 | 6,694
glioblastoma 30 | 5,792
medulloblastoma, large-cell 30 | 6,241
lung cancer 29 | 4,740
atypical teratoid / rhabdoid tumor 25 | 5,112
ependymoma 22 | 4,679
Breast cancer 21 | 3,577
group 3 medulloblastoma 20 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,290
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
malignant mesothelioma 19 | 3,232
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,954
non-small cell lung cancer 16 | 2,890
oligodendroglioma 16 | 2,850
pancreatic cancer 16 | 2,398
interstitial cystitis 15 | 2,312
Astrocytoma, Pilocytic 14 | 3,081
Emery-Dreifuss muscular dystrophy 14 | 23
Autosomal recessive predisposition 13 | 1,442
lung adenocarcinoma 13 | 2,716
lung carcinoma 13 | 2,843
tuberculosis 13 | 2,010
Cancer 12 | 2,499
Multiple myeloma 12 | 1,332
acute quadriplegic myopathy 12 | 1,158
astrocytic glioma 12 | 2,597
invasive ductal carcinoma 12 | 2,950
primitive neuroectodermal tumor 12 | 3,035
Kidney cancer 11 | 2,613
colon cancer 11 | 1,478
subependymal giant cell astrocytoma 11 | 2,287
Progeria 10 | 25
ductal carcinoma in situ 10 | 1,744
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
primary pancreatic ductal adenocarcinoma 10 | 1,108
Rheumatoid arthritis 9 | 1,191
Waldenstrons macroglobulinemia 9 | 765
Atopic dermatitis 8 | 952
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Pick disease 8 | 1,894
adrenocortical carcinoma 8 | 1,428
dermatomyositis 8 | 966
group 4 medulloblastoma 8 | 1,855
juvenile dermatomyositis 8 | 1,187
ulcerative colitis 8 | 1,819
Bipolar Disorder 7 | 666
Orbital separation excessive 7 | 244
Short stature 7 | 531
Vascular disease 7 | 319
cystic fibrosis 7 | 1,695
gastric carcinoma 7 | 807
pediatric high grade glioma 7 | 1,064
primary Sjogren syndrome 7 | 735
Cardiomyopathy 6 | 116
Creatine phosphokinase serum increased 6 | 110
Duchenne muscular dystrophy 6 | 601
Elevated creatine kinase 6 | 110
Epilepsy 6 | 792
Failure to gain weight 6 | 365
Infertility 6 | 188
Neurodegenerative disease 6 | 414
Pediatric failure to thrive 6 | 365
aldosterone-producing adenoma 6 | 665
breast carcinoma 6 | 1,637
diabetes mellitus 6 | 1,728
nasopharyngeal carcinoma 6 | 1,058
spina bifida 6 | 1,074
Acquired scoliosis 5 | 281
Amyotrophic lateral sclerosis 5 | 451
Chronic Lymphocytic Leukemia 5 | 262
Curvature of spine 5 | 282
Depressive disorder 5 | 409
Hypoplastic mandible condyle 5 | 275
Lipodystrophy 5 | 40
Liver cancer 5 | 604
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Multiple Sclerosis 5 | 540
Muscular Dystrophy, Emery-Dreifuss 5 | 5
Muscular dystrophy 5 | 75
Pelger-Huet anomaly 5 | 8
acute myeloid leukemia 5 | 783
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
mucosa-associated lymphoid tissue lymphoma 5 | 484
pituitary cancer 5 | 1,972
Byzanthine arch palate 4 | 194
Cardiomyopathy, Dilated 4 | 83
Parkinson's disease 4 | 392
Schizophrenia 4 | 1,160
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737

Tissue

Endocrine System 82 | 18,159
Liver and Pancreas 82 | 16,750
Male tissues 79 | 17,142
Digestive Tract 78 | 17,369
Female tissues 78 | 17,400
Skin and soft tissues 78 | 17,230
Nervous System 77 | 16,725
Blood and immune system 75 | 16,909
Respiratory system 74 | 16,393
Urinary Tract 74 | 16,678
Cardiovascular System 69 | 15,192

Target Family

Non-IDG 51 | 12,091
Enzyme 13 | 4,145
Ion Channel 11 | 344
Transcription Factor 4 | 1,400
Epigenetic 3 | 242
Transporter 2 | 473
GPCR 1 | 408

Compartment GO Term

Nuclear inner membrane 85 | 85
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lamina-associated polypeptide 2, isoform alpha TMPO Tbio Non-IDG -2.11834 246.0 283
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
Lamina-associated polypeptide 2, isoforms beta/gamma TMPO Tbio Non-IDG -2.11834 246.0 283
Desumoylating isopeptidase 2 DESI2 Tbio Enzyme -2.81944 648.8 75
Transmembrane protein 43 TMEM43 Tbio Non-IDG -1.19270 17.2 71
Protein ATP1B4 ATP1B4 Tdark Transporter -0.67056 4.78 35
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.77874 581.3 185
SUN domain-containing protein 1 SUN1 Tbio Non-IDG -1.74780 53.6 58
E3 ubiquitin-protein ligase RNF13 RNF13 Tbio Enzyme -0.84775 9.69 90