Development Level

Tbio 12 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal hair texture 1 | 4
abnormal heart morphology 1 | 162
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased heart rate 1 | 18
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
female infertility 1 | 60
hypoactivity 1 | 132
increased circulating aspartat... 1 | 15
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499
prolonged RR interval 1 | 8

Disease

Carcinoma 10 | 11,493
ovarian cancer 9 | 8,520
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
osteosarcoma 6 | 7,950
Kidney cancer 5 | 2,613
Multiple myeloma 5 | 1,332
medulloblastoma, large-cell 5 | 6,241
psoriasis 5 | 6,694
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
Ataxia, Appendicular 3 | 25
Ataxia, Truncal 3 | 21
Cancer 3 | 2,499
Deglutition Disorders 3 | 132
Dysarthria 3 | 192
Neurodegenerative disease 3 | 414
Progressive disorder 3 | 142
Waldenstrons macroglobulinemia 3 | 765
dermatomyositis 3 | 966
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
oligodendroglioma 3 | 2,850
tuberculosis 3 | 2,010
Adult onset 2 | 82
Amyotrophic lateral sclerosis 2 | 451
Aplastic Anemia 2 | 21
Atrophy of cerebellum 2 | 103
Attention deficit hyperactivity disorder 2 | 278
Autosomal dominant cerebellar ataxia 2 | 33
Autosomal recessive predisposition 2 | 1,442
Babinski Reflex 2 | 100
Blepharoptosis 2 | 231
Breast cancer 2 | 3,578
Cerebellar Ataxia 2 | 304
Cerebellar degeneration 2 | 103
Choreatic disease 2 | 52
Decreased vibratory sense 2 | 7
Dilated fourth ventricle 2 | 4
Distal amyotrophy 2 | 51
Dysmetric saccades 2 | 9
Impaired horizontal smooth pursuit 2 | 6
Infratentorial atrophy 2 | 103
Nerve Degeneration 2 | 121
Nijmegen breakage syndrome 2 | 24
Pick disease 2 | 1,894
Progressive cerebellar ataxia 2 | 13
Rheumatoid arthritis 2 | 1,191
Sphincter disturbances 2 | 16
Spinocerebellar Ataxias 2 | 34
Spinocerebellar ataxia type 1 2 | 16
Spinocerebellar tract degeneration 2 | 4
Supranuclear ophthalmoplegia 2 | 4
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Acute necrotizing encephalitis 1 | 2
Ataxia telangiectasia 1 | 34
Birthmark 1 | 35
Bronchiectasis 1 | 64
Cafe-au-Lait Spots 1 | 37
Cerebellar Dysmetria 1 | 56
Choanal Atresia 1 | 42
Chromosome Breakage 1 | 36
Diplopia 1 | 8
Dysdiadochokinesis 1 | 25
Gait, Unsteady 1 | 29
Hemophagocytic lymphohistiocytosis 1 | 30
Hereditary Breast and Ovarian Cancer Syndrome 1 | 14
Increased chromosomal breakage 1 | 27
Inflammatory myofibroblastic tumor 1 | 8
Lichen planus 1 | 16
Mask-like facies 1 | 25
Mastoiditis 1 | 8
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
Nystagmus, End-Position 1 | 12
Olivopontocerebellar atrophy 1 | 9
Ovarian Failure, Premature 1 | 9
PARKINSON DISEASE, LATE-ONSET 1 | 20
Papillary thyroid carcinoma 1 | 43
Postural instability 1 | 19
Recurrent bronchitis 1 | 23
Restless legs syndrome 1 | 27
Sinusitis 1 | 65
Slowed saccades 1 | 12
Spinocerebellar ataxia type 2 1 | 23
Stomatitis 1 | 21
Syphilis 1 | 17
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Werner syndrome 1 | 29
clinical depression 1 | 6

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 4 | 4,145
Epigenetic 1 | 242

Compartment GO Term

Nuclear inclusion body 12 | 12
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.57250 40.4 202
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120
Nuclear pore complex protein Nup153 NUP153 Tbio Non-IDG -2.14396 129.9 100
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.26305 200.9 189
SMC5-SMC6 complex localization factor protein 1 SLF1 Tbio Non-IDG -0.93112 9.24 119
E3 ubiquitin-protein ligase RAD18 RAD18 Tbio Enzyme -2.22905 169.1 271
E3 ubiquitin-protein ligase CHIP STUB1 Tbio Enzyme -2.96877 926.8 351
E3 SUMO-protein ligase RanBP2 RANBP2 Tbio Enzyme -2.24609 178.6 172
Nibrin NBN Tbio Non-IDG -1.95649 97.2 1094