Development Level

Tbio 20 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
preweaning lethality, complete... 3 | 979
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
absent spleen 1 | 3
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased heart rate 1 | 18
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
increased circulating choleste... 1 | 66
increased mean corpuscular hem... 1 | 36
prolonged RR interval 1 | 8
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 15 | 8,520
Carcinoma 14 | 11,493
Cancer 13 | 2,499
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
glioblastoma 11 | 5,792
osteosarcoma 11 | 7,950
group 3 medulloblastoma 10 | 4,104
lung adenocarcinoma 9 | 2,716
malignant mesothelioma 9 | 3,232
psoriasis 9 | 6,694
atypical teratoid / rhabdoid tumor 8 | 5,112
Breast cancer 7 | 3,578
Rheumatoid arthritis 7 | 1,191
Waldenstrons macroglobulinemia 7 | 765
diabetes mellitus 7 | 1,728
Pick disease 6 | 1,894
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Alzheimer's disease 5 | 658
Kidney cancer 5 | 2,613
adrenocortical carcinoma 5 | 1,428
dermatomyositis 5 | 966
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
primitive neuroectodermal tumor 5 | 3,035
Multiple myeloma 4 | 1,332
Schizophrenia 4 | 1,160
acute myeloid leukemia 4 | 783
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
hepatocellular carcinoma 4 | 547
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
Prostatic Neoplasms 3 | 495
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung carcinoma 3 | 2,843
primary pancreatic ductal adenocarcinoma 3 | 1,109
ulcerative colitis 3 | 1,819
Abnormality of metabolism/homeostasis 2 | 134
Adenoid Cystic Carcinoma 2 | 99
Alpha thalassemia-X-linked intellectual disability syndrome 2 | 3
Astrocytoma, Pilocytic 2 | 3,081
Carcinoma, Adenoid Cystic 2 | 99
Crohn's disease 2 | 321
Decreased projection of midface 2 | 105
Drooling 2 | 27
Endometriosis 2 | 540
Everted lower lip vermilion 2 | 54
Fatigue 2 | 182
Huntington's disease 2 | 76
Hypotrophic malar bone 2 | 129
Hypotrophic midface 2 | 105
Immune system cancer 2 | 140
Intellectual disability 2 | 1,016
Liver cancer 2 | 604
Lymphoid leukemia 2 | 160
Malar flattening 2 | 129
Mesothelioma, Malignant 2 | 105
Midface retrusion 2 | 105
Mood Disorders 2 | 184
Obesity 2 | 678
Orbital separation excessive 2 | 244
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Parkinson's disease 2 | 392
Protruding lower lip 2 | 54
Sensorineural Hearing Loss (disorder) 2 | 284
Sialorrhea 2 | 28
Small midface 2 | 105
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
oligodendroglioma 2 | 2,850
ovarian neoplasm 2 | 99
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
permanent atrial fibrillation 2 | 45
primary Sjogren syndrome 2 | 735
progressive supranuclear palsy 2 | 676
sarcoidosis 2 | 370
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
Asbestosis 1 | 20
Bloom syndrome 1 | 29
Cystic nephroma 1 | 5
Disturbance in mood 1 | 3
Dysphasia 1 | 23
Metabolic Syndrome 1 | 20
Persistent hyperplastic primary vitreous 1 | 20
Postnatal growth retardation 1 | 57

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Epigenetic 11 | 242
Non-IDG 10 | 12,091
Enzyme 2 | 4,145
Transcription Factor 2 | 1,400

Compartment GO Term

Nuclear heterochromatin 25 | 25
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase KMT5C KMT5C Tchem Epigenetic 1.18 0.06 46
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.57250 40.4 202
Histone H1.5 HIST1H1B Tbio Non-IDG -2.13224 134.1 103
Mesothelin MSLN Tbio Non-IDG -2.66061 452.1 542
10 kDa heat shock protein, mitochondrial HSPE1 Tbio Non-IDG -3.03566 1027.8 403
Forkhead box protein C1 FOXC1 Tbio Transcription Factor -2.28586 201.8 314
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
PC4 and SFRS1-interacting protein PSIP1 Tbio Epigenetic -2.56190 391.2 150
Transcriptional regulator ATRX ATRX Tbio Non-IDG -2.85277 705.9 248
Core histone macro-H2A.1 H2AFY Tbio Non-IDG -1.78572 69.6 95