Development Level

Tbio 277 | 10,625
Tdark 71 | 7,003
Tchem 45 | 1,890
Tclin 15 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 16 | 633
preweaning lethality, incomple... 10 | 260
abnormal behavior 7 | 226
decreased bone mineral content 7 | 157
decreased body weight 6 | 174
decreased grip strength 6 | 123
decreased rib number 6 | 59
decreased lean body mass 5 | 195
increased mean corpuscular hem... 5 | 93
abnormal bone structure 4 | 131
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
hypoactivity 4 | 89
increased circulating alkaline... 4 | 119
abnormal sleep behavior 3 | 63
abnormal snout morphology 3 | 18
decreased body length 3 | 108
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 77
decreased circulating alkaline... 3 | 41
decreased lumbar vertebrae num... 3 | 62
impaired glucose tolerance 3 | 52
increased blood urea nitrogen ... 3 | 44
increased lean body mass 3 | 107
increased mean corpuscular vol... 3 | 91
increased sacral vertebrae num... 3 | 62
small thymus 3 | 11
tremors 3 | 34
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal coping response 2 | 12
abnormal heart left ventricle ... 2 | 20
abnormal lens morphology 2 | 73
abnormal locomotor activation 2 | 26
abnormal motor coordination/ b... 2 | 4
abnormal retina morphology 2 | 100
decreased basophil cell number 2 | 11
decreased caudal vertebrae num... 2 | 49
decreased circulating aspartat... 2 | 27
decreased circulating glycerol... 2 | 19
decreased fasted circulating g... 2 | 49
decreased hematocrit 2 | 25
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased pulmonary respirator... 2 | 4
enlarged heart 2 | 111
enlarged stomach 2 | 2
hydrops fetalis 2 | 22
hyperactivity 2 | 108
immune system phenotype 2 | 17
increased circulating creatini... 2 | 29
increased circulating triglyce... 2 | 24
increased grip strength 2 | 83
increased or absent threshold ... 2 | 128
lethargy 2 | 5
short tibia 2 | 82
thrombocytopenia 2 | 46
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal limb bud morphology 1 | 15
abnormal retinal inner nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
cataract 1 | 26
corneal opacity 1 | 25
cyanosis 1 | 6
decreased CD8-positive, alpha-... 1 | 26
decreased KLRG1-positive NK ce... 1 | 9
decreased T cell number 1 | 31
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased thoracic vertebrae n... 1 | 7
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
female infertility 1 | 34
hemorrhage 1 | 12
impaired righting response 1 | 19
increased CD4-positive, CD25-p... 1 | 18
increased bone mineral density 1 | 52
increased circulating choleste... 1 | 53
increased lactate dehydrogenas... 1 | 3
irregularly shaped pupil 1 | 7
microphthalmia 1 | 15
premature death 1 | 5
shortened PQ interval 1 | 6
small adrenal glands 1 | 15
vertebral fusion 1 | 23

Disease

ovarian cancer 231 | 8,484
osteosarcoma 205 | 7,933
medulloblastoma, large-cell 168 | 6,234
psoriasis 154 | 6,685
lung cancer 144 | 4,466
glioblastoma 134 | 5,572
atypical teratoid / rhabdoid tumor 104 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 91 | 3,289
Breast cancer 88 | 3,094
malignant mesothelioma 87 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 85 | 2,988
group 3 medulloblastoma 84 | 2,254
invasive ductal carcinoma 79 | 2,950
non-small cell lung cancer 77 | 2,798
primitive neuroectodermal tumor 75 | 3,031
pediatric high grade glioma 73 | 2,712
Cancer 71 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 71 | 2,956
oligodendroglioma 71 | 2,849
pancreatic cancer 62 | 2,300
ependymoma 61 | 2,514
lung adenocarcinoma 60 | 2,713
pilocytic astrocytoma 59 | 3,086
Carcinoma 57 | 2,147
Multiple myeloma 57 | 1,327
subependymal giant cell astrocytoma 57 | 2,287
Pick disease 56 | 1,893
lung carcinoma 51 | 2,844
acute quadriplegic myopathy 49 | 1,157
astrocytic glioma 49 | 2,241
dermatomyositis 49 | 933
colon cancer 48 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,795
group 4 medulloblastoma 45 | 1,875
primary pancreatic ductal adenocarcinoma 45 | 1,271
breast carcinoma 44 | 1,614
ductal carcinoma in situ 43 | 1,745
interstitial cystitis 43 | 2,299
ulcerative colitis 42 | 2,087
adult high grade glioma 41 | 2,148
juvenile dermatomyositis 40 | 1,189
astrocytoma 37 | 1,493
tuberculosis 37 | 1,557
Rheumatoid Arthritis 36 | 1,160
pituitary cancer 36 | 1,972
adrenocortical carcinoma 34 | 1,427
medulloblastoma 34 | 1,524
posterior fossa group A ependymoma 34 | 1,511
Waldenstrons macroglobulinemia 33 | 765
cystic fibrosis 33 | 1,665
nasopharyngeal carcinoma 33 | 1,056
atypical teratoid/rhabdoid tumor 29 | 1,095
cutaneous lupus erythematosus 28 | 1,056
diabetes mellitus 27 | 1,663
primary Sjogren syndrome 26 | 789
sonic hedgehog group medulloblastoma 26 | 1,482
aldosterone-producing adenoma 25 | 664
posterior fossa group B ependymoma 24 | 1,530
Alzheimer's disease 23 | 644
Atopic dermatitis 22 | 944
Neurodegenerative disease 22 | 383
acute myeloid leukemia 22 | 780
non primary Sjogren syndrome sicca 22 | 840
Amyotrophic Lateral Sclerosis 21 | 431
Down syndrome 21 | 548
tuberculosis and treatment for 6 months 21 | 686
Mammary Neoplasms 20 | 410
esophageal adenocarcinoma 20 | 737
gastric carcinoma 20 | 832
progressive supranuclear palsy 20 | 674
Duchenne muscular dystrophy 18 | 602
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 499
active Crohn's disease 17 | 918
spina bifida 17 | 1,064
Emery-Dreifuss muscular dystrophy 15 | 24
Prostatic Neoplasms 15 | 471
Vascular disease 15 | 281
hereditary spastic paraplegia 15 | 313
Asthma 14 | 349
Endometriosis 14 | 535
Schizophrenia 14 | 501
tuberculosis and treatment for 3 months 14 | 327
IGA Glomerulonephritis 13 | 454
active ulcerative colitis 13 | 477
mucosa-associated lymphoid tissue lymphoma 13 | 480
sarcoidosis 13 | 358
Epilepsy 12 | 346
Chronic Lymphocytic Leukemia 11 | 242
Intellectual disability 11 | 573
Multiple Sclerosis 11 | 498
Obesity 11 | 616
Parkinson's disease 11 | 364
Crohn's disease 10 | 304
HIV Infections 10 | 100
Influenza 10 | 142
inflammatory breast cancer 10 | 404
Diabetes Mellitus, Non-Insulin-Dependent 9 | 157
Stomach Neoplasms 9 | 282
hepatocellular carcinoma 9 | 532
pancreatic carcinoma 9 | 567

Tissue

Nervous System 402 | 18,561
Blood and immune system 401 | 17,995
Endocrine System 401 | 18,512
Female tissues 401 | 18,647
Liver and Pancreas 400 | 18,136
Male tissues 400 | 17,969
Urinary Tract 400 | 18,444
Digestive Tract 399 | 18,473
Cardiovascular System 397 | 17,958
Skin and soft tissues 396 | 18,115
Respiratory system 394 | 17,484

Target Family

Non-IDG 254 | 11,971
Enzyme 82 | 4,146
Transcription Factor 20 | 1,400
Ion Channel 15 | 341
Kinase 15 | 634
Transporter 8 | 473
Epigenetic 6 | 242
GPCR 6 | 406
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

Nuclear envelope 408 | 408
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Testis-specific gene 10 protein TSGA10 Tbio Non-IDG -1.05563 13.1 82
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.17754 15.9 54
Nucleolar GTP-binding protein 1 GTPBP4 Tbio Non-IDG -3.21425 1443.3 95
Putative GRINL1B complex locus protein 2 GCOM2 Tdark Non-IDG -1.14190 15.0 0
Transmembrane channel-like protein 8 TMC8 Tbio Ion Channel -1.45295 32.2 147
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Ceramide synthase 3 CERS3 Tbio Transcription Factor -0.90774 9.32 99
Pre-mRNA-splicing factor 38A PRPF38A Tdark Non-IDG -0.69167 4.80 72
Emerin EMD Tbio Non-IDG -2.77469 617.6 238