Development Level

Tbio 316 | 11,651
Tdark 59 | 6,593
Tchem 36 | 1,388
Tclin 16 | 612

Collection

RFA-RM-18-021 3 | 328
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 26 | 979
preweaning lethality, incomple... 20 | 499
abnormal behavior 9 | 298
decreased vertical activity 6 | 208
enlarged heart 6 | 210
increased lean body mass 6 | 172
increased total body fat amoun... 6 | 134
abnormal bone structure 5 | 187
abnormal embryo size 5 | 220
abnormal heart morphology 5 | 162
decreased body weight 5 | 161
decreased bone mineral content 5 | 151
decreased lean body mass 5 | 135
decreased total body fat amoun... 5 | 207
embryonic lethality prior to t... 5 | 278
hypoactivity 5 | 132
decreased circulating alkaline... 4 | 46
decreased hematocrit 4 | 46
decreased hemoglobin content 4 | 68
edema 4 | 59
hyperactivity 4 | 148
impaired glucose tolerance 4 | 75
increased circulating alkaline... 4 | 122
increased mean corpuscular hem... 4 | 96
increased startle reflex 4 | 112
male infertility 4 | 123
tremors 4 | 39
abnormal gait 3 | 69
abnormal sleep behavior 3 | 70
abnormal snout morphology 3 | 23
cataract 3 | 92
decreased basophil cell number 3 | 16
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased grip strength 3 | 116
decreased lymphocyte cell numb... 3 | 83
increased fasted circulating g... 3 | 76
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
small thymus 3 | 16
abnormal bone mineralization 2 | 38
abnormal lens morphology 2 | 81
abnormal locomotor behavior 2 | 24
abnormal placenta size 2 | 20
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating glycerol... 2 | 16
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased heart weight 2 | 27
decreased leukocyte cell numbe... 2 | 73
decreased pulmonary respirator... 2 | 5
embryonic lethality prior to o... 2 | 239
enlarged stomach 2 | 2
female infertility 2 | 60
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased circulating triglyce... 2 | 42
increased red blood cell distr... 2 | 34
short tibia 2 | 97
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal whole-body plethysmog... 1 | 4
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating creatine... 1 | 5
increased circulating serum al... 1 | 22
increased eosinophil cell numb... 1 | 11
long tibia 1 | 25
microphthalmia 1 | 26
vertebral fusion 1 | 23

Disease

Carcinoma 288 | 11,493
ovarian cancer 242 | 8,520
osteosarcoma 220 | 7,950
medulloblastoma, large-cell 184 | 6,241
psoriasis 168 | 6,694
lung cancer 153 | 4,740
glioblastoma 152 | 5,792
atypical teratoid / rhabdoid tumor 134 | 5,112
group 3 medulloblastoma 130 | 4,104
ependymoma 107 | 4,679
Breast cancer 105 | 3,578
malignant mesothelioma 99 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 93 | 3,291
adult high grade glioma 92 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 89 | 2,989
invasive ductal carcinoma 87 | 2,951
Cancer 77 | 2,499
non-small cell lung cancer 77 | 2,890
primitive neuroectodermal tumor 76 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 75 | 2,955
oligodendroglioma 73 | 2,850
pancreatic cancer 65 | 2,398
Astrocytoma, Pilocytic 63 | 3,081
Kidney cancer 63 | 2,613
Multiple myeloma 61 | 1,332
lung adenocarcinoma 61 | 2,716
astrocytic glioma 59 | 2,597
Pick disease 57 | 1,894
subependymal giant cell astrocytoma 57 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 56 | 1,962
tuberculosis 56 | 2,010
acute quadriplegic myopathy 54 | 1,158
dermatomyositis 52 | 966
breast carcinoma 51 | 1,638
lung carcinoma 51 | 2,843
colon cancer 50 | 1,478
group 4 medulloblastoma 49 | 1,855
interstitial cystitis 47 | 2,312
ductal carcinoma in situ 46 | 1,745
juvenile dermatomyositis 46 | 1,187
ulcerative colitis 43 | 1,819
Rheumatoid arthritis 40 | 1,191
adrenocortical carcinoma 39 | 1,428
cystic fibrosis 38 | 1,696
nasopharyngeal carcinoma 38 | 1,058
primary pancreatic ductal adenocarcinoma 38 | 1,109
pituitary cancer 37 | 1,972
Autosomal recessive predisposition 35 | 1,442
Waldenstrons macroglobulinemia 34 | 765
Schizophrenia 32 | 1,160
diabetes mellitus 32 | 1,728
pediatric high grade glioma 31 | 1,064
Amyotrophic lateral sclerosis 30 | 451
astrocytoma 29 | 1,146
cutaneous lupus erythematosus 29 | 1,057
Alzheimer's disease 28 | 658
Atopic dermatitis 26 | 952
Epilepsy 26 | 792
non primary Sjogren syndrome sicca 25 | 891
primary Sjogren syndrome 25 | 735
Liver Cirrhosis, Experimental 24 | 769
aldosterone-producing adenoma 24 | 665
Bipolar Disorder 23 | 666
Intellectual disability 23 | 1,016
Neurodegenerative disease 23 | 414
Mammary Neoplasms 22 | 425
acute myeloid leukemia 22 | 783
esophageal adenocarcinoma 22 | 737
Breast Neoplasms 21 | 445
Duchenne muscular dystrophy 21 | 601
Prostatic Neoplasms 21 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 21 | 510
Down syndrome 20 | 499
Cognitive delay 19 | 608
Global developmental delay 19 | 608
Mental and motor retardation 19 | 608
gastric carcinoma 19 | 807
progressive supranuclear palsy 19 | 676
Seizures 18 | 596
active ulcerative colitis 18 | 764
spina bifida 18 | 1,074
Depressive disorder 17 | 409
active Crohn's disease 17 | 922
Asthma 16 | 385
hereditary spastic paraplegia 16 | 318
Chronic Lymphocytic Leukemia 15 | 262
Dull intelligence 15 | 645
Emery-Dreifuss muscular dystrophy 15 | 23
Liver cancer 15 | 604
Low intelligence 15 | 645
Melanoma 15 | 711
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Obesity 15 | 678
Orbital separation excessive 15 | 244
Poor school performance 15 | 645
sarcoidosis 15 | 370
Parkinson's disease 14 | 392
Vascular disease 14 | 319
sonic hedgehog group medulloblastoma 14 | 467

Tissue

Endocrine System 416 | 18,159
Digestive Tract 412 | 17,369
Female tissues 412 | 17,400
Liver and Pancreas 411 | 16,750
Male tissues 409 | 17,142
Skin and soft tissues 407 | 17,230
Blood and immune system 405 | 16,909
Urinary Tract 404 | 16,678
Nervous System 403 | 16,725
Respiratory system 402 | 16,393
Cardiovascular System 384 | 15,192

Target Family

Non-IDG 262 | 12,091
Enzyme 87 | 4,145
Transcription Factor 24 | 1,400
Ion Channel 16 | 344
Kinase 13 | 634
Epigenetic 8 | 242
Transporter 8 | 473
GPCR 7 | 408
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

Nuclear envelope 427 | 427
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Lamina-associated polypeptide 2, isoform alpha TMPO Tbio Non-IDG -2.11834 246.0 283
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
Protein KASH5 CCDC155 Tdark Non-IDG -0.58600 3.79 39
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Exportin-4 XPO4 Tbio Non-IDG -1.62873 40.7 26
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
Ran-specific GTPase-activating protein RANBP1 Tbio Enzyme -1.80548 64.8 193
Lamina-associated polypeptide 2, isoforms beta/gamma TMPO Tbio Non-IDG -2.11834 246.0 283
Zinc finger protein 354C ZNF354C Tdark Transcription Factor -0.70660 4.42 43