Development Level

Tbio 24 | 11,445
Tchem 6 | 1,598

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased vertical activity 2 | 208
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal incisor morphology 1 | 4
abnormal lens morphology 1 | 81
abnormal skin morphology 1 | 50
abnormal vertebral arch morpho... 1 | 9
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased kidney weight 1 | 1
decreased leukocyte cell numbe... 1 | 73
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
female infertility 1 | 60
fusion of vertebral arches 1 | 7
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased grip strength 1 | 41
increased heart rate 1 | 23
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased vertical activity 1 | 24
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
shortened RR interval 1 | 17
thrombocytopenia 1 | 56
vertebral transformation 1 | 12

Disease

Carcinoma 22 | 11,493
ovarian cancer 20 | 8,520
osteosarcoma 14 | 7,950
psoriasis 13 | 6,694
Cancer 10 | 2,499
group 3 medulloblastoma 10 | 4,104
medulloblastoma, large-cell 9 | 6,241
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
Breast cancer 7 | 3,578
Pick disease 7 | 1,894
astrocytic glioma 7 | 2,597
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
Kidney cancer 6 | 2,613
oligodendroglioma 6 | 2,850
Intellectual disability 5 | 1,016
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
subependymal giant cell astrocytoma 5 | 2,287
Dressler's syndrome 4 | 6
Leukemia 4 | 104
Myocardial Infarction 4 | 151
Myopathy 4 | 185
Rheumatoid arthritis 4 | 1,191
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
progressive supranuclear palsy 4 | 676
Acquired immunodeficiency syndrome 3 | 197
Myxedema 3 | 11
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Acute coronary syndrome 2 | 39
Autosomal recessive predisposition 2 | 1,442
Cockayne syndrome 2 | 60
Colonic Neoplasms 2 | 142
Congenital hereditary endothelial dystrophy of cornea 2 | 8
Dull intelligence 2 | 645
Hypertrophy, Left Ventricular 2 | 24
Left Ventricular Hypertrophy 2 | 47
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Photosensitive trichothiodystrophy 2 | 30
Poor school performance 2 | 645
Reticular dysgenesis 2 | 7
Schizophrenia 2 | 1,160
Xeroderma pigmentosum group B 2 | 20
chronic lymphosyte leukemia 2 | 204
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
interstitial lung disease 2 | 298
invasive ductal carcinoma 2 | 2,951
pancreatic carcinoma 2 | 562
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
Absent radius 1 | 15
Acute contagious conjunctivitis 1 | 7
Animal Mammary Neoplasms 1 | 136
Brachydactyly 1 | 156
Broad thumbs 1 | 28
COPD 1 | 118
Carpal synostosis 1 | 12
Cow milk allergy 1 | 1
Coxa valga 1 | 22
Decreased platelet count 1 | 111
Eosinophilia 1 | 28
Genu varum 1 | 29
Horseshoe Kidney 1 | 16
Hypotrophic malar bone 1 | 129
Lung diseases 1 | 50
Malar flattening 1 | 129
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Meckel Diverticulum 1 | 5
Neuritis 1 | 5
Pancreatic Cyst 1 | 4
Radial aplasia 1 | 15
Roberts syndrome 1 | 15
Seborrheic dermatitis 1 | 31
Tibial torsion 1 | 1
sarcoidosis 1 | 370

Tissue

Blood and immune system 30 | 16,909
Cardiovascular System 30 | 15,192
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Respiratory system 29 | 16,393

Target Family

Non-IDG 15 | 12,091
Kinase 8 | 634
Enzyme 3 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

Compartment GO Term

Nuclear cyclin-dependent prote... 30 | 30
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210
AF4/FMR2 family member 3 AFF3 Tbio Transcription Factor -1.37981 25.3 50
AF4/FMR2 family member 1 AFF1 Tbio Transcription Factor -2.60388 403.1 201
Cyclin-dependent kinase 12 CDK12 Tchem Kinase -1.38476 29.4 157
HIV Tat-specific factor 1 HTATSF1 Tbio Non-IDG -1.13052 11.7 211
Transcription elongation factor SPT5 SUPT5H Tbio Non-IDG -1.92374 80.5 135
Protein ENL MLLT1 Tbio Non-IDG -2.46931 301.2 119
La-related protein 7 LARP7 Tbio Non-IDG -1.37179 13.8 144
AF4/FMR2 family member 4 AFF4 Tbio Transcription Factor -2.54994 350.8 174