Development Level

Tbio 286 | 11,178
Tchem 63 | 1,885
Tdark 47 | 6,569
Tclin 19 | 612

IMPC Phenotype

preweaning lethality, complete... 51 | 979
embryonic lethality prior to o... 19 | 239
embryonic lethality prior to t... 19 | 278
preweaning lethality, incomple... 13 | 499
abnormal behavior 8 | 298
increased startle reflex 8 | 112
male infertility 8 | 123
abnormal bone structure 6 | 187
abnormal embryo size 6 | 220
decreased vertical activity 6 | 208
decreased bone mineral content 5 | 151
decreased total body fat amoun... 5 | 207
abnormal embryo turning 4 | 31
decreased body weight 4 | 161
decreased circulating glucose ... 4 | 126
embryonic growth retardation 4 | 106
female infertility 4 | 60
hyperactivity 4 | 148
increased bone mineral content 4 | 108
increased bone mineral density 4 | 72
increased mean corpuscular hem... 4 | 96
increased mean corpuscular vol... 4 | 92
prenatal lethality prior to he... 4 | 87
small testis 4 | 58
abnormal eye morphology 3 | 68
abnormal gait 3 | 69
abnormal seminal vesicle morph... 3 | 114
abnormal spleen morphology 3 | 55
cardiovascular system phenotyp... 3 | 36
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 53
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
decreased mean corpuscular vol... 3 | 79
decreased prepulse inhibition 3 | 82
enlarged heart 3 | 210
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
small spleen 3 | 19
abnormal blood vessel morpholo... 2 | 5
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal craniofacial morpholo... 2 | 33
abnormal cranium morphology 2 | 36
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
absent pinna reflex 2 | 23
decreased circulating alanine ... 2 | 47
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased fasted circulating g... 2 | 65
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased mean platelet volume 2 | 45
increased neutrophil cell numb... 2 | 46
pale yolk sac 2 | 25
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal ear morphology 1 | 9
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
decreased body length 1 | 101
decreased circulating creatine... 1 | 4
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased fluid intake 1 | 3
decreased mean corpuscular hem... 1 | 31
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
impaired righting response 1 | 26
increased body length 1 | 32
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating magnesiu... 1 | 10
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 262 | 11,192
ovarian cancer 228 | 8,297
osteosarcoma 209 | 7,766
psoriasis 170 | 6,514
lung cancer 169 | 4,607
medulloblastoma, large-cell 169 | 6,086
glioblastoma 166 | 5,635
Cancer 151 | 2,388
group 3 medulloblastoma 148 | 4,002
atypical teratoid / rhabdoid tumor 145 | 4,971
Breast cancer 126 | 3,469
malignant mesothelioma 122 | 3,135
primitive neuroectodermal tumor 106 | 2,957
non-small cell lung cancer 96 | 2,799
ependymoma 91 | 4,559
lung adenocarcinoma 85 | 2,627
Kidney cancer 84 | 2,548
adult high grade glioma 82 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 79 | 3,204
invasive ductal carcinoma 77 | 2,867
intraductal papillary-mucinous carcinoma (IPMC) 71 | 2,902
breast carcinoma 59 | 1,589
Multiple myeloma 55 | 1,296
Intellectual disability 54 | 998
adrenocortical carcinoma 54 | 1,385
ductal carcinoma in situ 54 | 1,686
pancreatic cancer 53 | 2,322
colon cancer 52 | 1,428
oligodendroglioma 52 | 2,768
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,872
astrocytic glioma 44 | 2,530
astrocytoma 43 | 1,113
Short stature 42 | 514
Pick disease 41 | 1,856
pituitary cancer 41 | 1,915
Dull intelligence 40 | 634
Low intelligence 40 | 634
Mental Retardation 40 | 634
Mental deficiency 40 | 634
Poor school performance 40 | 634
Schizophrenia 40 | 1,136
Waldenstrons macroglobulinemia 40 | 742
diabetes mellitus 40 | 1,683
Astrocytoma, Pilocytic 39 | 3,006
Small head 38 | 366
nasopharyngeal carcinoma 38 | 1,024
subependymal giant cell astrocytoma 38 | 2,230
ulcerative colitis 38 | 1,765
Autosomal recessive predisposition 37 | 1,407
Cognitive delay 37 | 596
Global developmental delay 37 | 596
Mental and motor retardation 37 | 596
group 4 medulloblastoma 37 | 1,806
pediatric high grade glioma 37 | 1,035
Rheumatoid arthritis 35 | 1,156
dermatomyositis 35 | 941
acute quadriplegic myopathy 34 | 1,133
juvenile dermatomyositis 34 | 1,147
tuberculosis 34 | 1,963
lung carcinoma 33 | 2,755
Cryptorchidism 32 | 287
pancreatic ductal adenocarcinoma liver metastasis 32 | 1,911
Breast Neoplasms 31 | 423
Endometriosis 31 | 521
Mammary Neoplasms 31 | 403
Prostatic Neoplasms 31 | 472
interstitial cystitis 30 | 2,237
Epilepsy 29 | 775
Atopic dermatitis 27 | 915
acute myeloid leukemia 27 | 760
Fetal Growth Retardation 26 | 186
Infant, Small for Gestational Age 26 | 174
Intrauterine retardation 26 | 174
Melanoma 26 | 689
Muscle hypotonia 26 | 562
Seizures 26 | 584
non primary Sjogren syndrome sicca 26 | 861
hepatocellular carcinoma 25 | 536
Hypoplastic mandible condyle 23 | 273
Mandibular hypoplasia 23 | 273
Micrognathism 23 | 273
pancreatic carcinoma 23 | 555
Fanconi anemia 22 | 56
Liver cancer 22 | 589
Microcephaly 22 | 166
medulloblastoma 22 | 702
Stomach Neoplasms 21 | 287
gastric cancer 21 | 445
Obesity 20 | 655
Strabismus 20 | 265
aldosterone-producing adenoma 20 | 646
cystic fibrosis 20 | 1,629
primary Sjogren syndrome 20 | 710
Failure to gain weight 19 | 359
Pediatric failure to thrive 19 | 359
non-small cell lung carcinoma 19 | 302
spina bifida 19 | 1,053
Curvature of spine 18 | 275
Male infertility 18 | 199
cutaneous lupus erythematosus 18 | 1,016

Tissue

Endocrine System 411 | 18,159
Digestive Tract 404 | 17,369
Female tissues 403 | 17,400
Skin and soft tissues 402 | 17,230
Male tissues 399 | 17,142
Blood and immune system 398 | 16,909
Liver and Pancreas 393 | 16,750
Nervous System 390 | 16,725
Urinary Tract 390 | 16,678
Respiratory system 389 | 16,393
Cardiovascular System 378 | 15,192

Target Family

Non-IDG 225 | 12,091
Transcription Factor 69 | 1,400
Enzyme 53 | 4,145
Epigenetic 46 | 242
Kinase 12 | 634
Nuclear Receptor 8 | 48
TF/Epigenetic 1 | 38
Transporter 1 | 473

Compartment GO Term

Nuclear chromosome 415 | 415
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Histone H2A-Bbd type 2/3 H2AFB3 Tdark Non-IDG -0.25594 2.36 13
ATP-dependent DNA helicase DDX11 DDX11 Tbio Enzyme -1.05592 30.0 163
Chromobox protein homolog 1 CBX1 Tbio Epigenetic -2.31837 203.1 260
Microspherule protein 1 MCRS1 Tbio Non-IDG -1.40659 32.1 99
Transcription initiation factor TFIID subunit 1 TAF1 Tbio Kinase -2.64215 426.1 228
Zinc finger E-box-binding homeobox 2 ZEB2 Tbio Transcription Factor -2.49656 262.6 474
Histone H3.1t HIST3H3 Tbio Non-IDG -1.05426 10.9 1265
Nuclear receptor subfamily 1 group D member 1 NR1D1 Tchem Nuclear Receptor -1.95952 81.6 389