Development Level

Tbio 584 | 11,651
Tchem 72 | 1,388
Tdark 57 | 6,593
Tclin 12 | 612

Collection

RFA-RM-18-021 9 | 328
Kinase: IDG Consortium (Target... 8 | 125
Kinase: IDG Consortium (Comple... 5 | 37
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 80 | 979
preweaning lethality, incomple... 28 | 499
embryonic lethality prior to t... 20 | 278
embryonic lethality prior to o... 18 | 239
abnormal embryo size 15 | 220
decreased total body fat amoun... 15 | 207
abnormal behavior 14 | 298
enlarged heart 10 | 210
hypoactivity 10 | 132
increased startle reflex 10 | 112
increased lean body mass 9 | 172
decreased vertical activity 8 | 208
abnormal heart morphology 7 | 162
cataract 7 | 92
decreased body length 7 | 101
decreased body weight 7 | 161
decreased hemoglobin content 7 | 68
increased bone mineral content 7 | 108
increased mean corpuscular vol... 7 | 92
decreased circulating choleste... 6 | 93
decreased grip strength 6 | 116
prenatal lethality prior to he... 6 | 87
abnormal lens morphology 5 | 81
corneal opacity 5 | 32
decreased bone mineral content 5 | 151
decreased erythrocyte cell num... 5 | 62
decreased leukocyte cell numbe... 5 | 73
decreased prepulse inhibition 5 | 82
increased body length 5 | 32
increased bone mineral density 5 | 72
increased mean corpuscular hem... 5 | 96
increased mean platelet volume 5 | 45
abnormal bone structure 4 | 187
abnormal gait 4 | 69
abnormal retina morphology 4 | 71
abnormal seminal vesicle morph... 4 | 114
decreased bone mineral density 4 | 126
decreased circulating alanine ... 4 | 47
decreased circulating glucose ... 4 | 126
decreased circulating iron lev... 4 | 32
decreased lean body mass 4 | 135
hyperactivity 4 | 148
increased body weight 4 | 25
increased fasted circulating g... 4 | 76
increased heart weight 4 | 62
increased total body fat amoun... 4 | 134
male infertility 4 | 123
persistence of hyaloid vascula... 4 | 33
small testis 4 | 58
tremors 4 | 39
abnormal eye morphology 3 | 68
abnormal locomotor activation 3 | 16
abnormal skin morphology 3 | 50
anophthalmia 3 | 33
decreased blood urea nitrogen ... 3 | 51
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating alkaline... 3 | 46
decreased circulating aspartat... 3 | 34
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased eosinophil cell numb... 3 | 24
decreased fasted circulating g... 3 | 65
decreased hematocrit 3 | 46
decreased lymphocyte cell numb... 3 | 83
edema 3 | 59
embryonic growth retardation 3 | 106
impaired glucose tolerance 3 | 75
increased blood urea nitrogen ... 3 | 48
increased circulating HDL chol... 3 | 80
increased circulating calcium ... 3 | 34
increased circulating sodium l... 3 | 71
increased monocyte cell number 3 | 63
increased neutrophil cell numb... 3 | 46
increased or absent threshold ... 3 | 101
limb grasping 3 | 41
pallor 3 | 34
vertebral transformation 3 | 12
abnormal behavioral response t... 2 | 66
abnormal coat-hair pigmentatio... 2 | 64
abnormal epididymis morphology 2 | 42
abnormal heart left ventricle ... 2 | 16
abnormal neural tube morpholog... 2 | 12
abnormal testis morphology 2 | 43
cardiovascular system phenotyp... 2 | 36
decreased circulating chloride... 2 | 30
decreased circulating fructosa... 2 | 30
decreased circulating triglyce... 2 | 79
decreased lactate dehydrogenas... 2 | 16
decreased red blood cell distr... 2 | 41
enlarged spleen 2 | 41
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating serum al... 2 | 22
increased circulating total pr... 2 | 28
increased hemoglobin content 2 | 45
small thymus 2 | 16

Disease

Carcinoma 521 | 11,493
ovarian cancer 458 | 8,520
osteosarcoma 390 | 7,950
psoriasis 288 | 6,694
medulloblastoma, large-cell 275 | 6,241
glioblastoma 260 | 5,792
group 3 medulloblastoma 231 | 4,104
lung cancer 231 | 4,740
atypical teratoid / rhabdoid tumor 218 | 5,112
ependymoma 186 | 4,679
Breast cancer 179 | 3,578
malignant mesothelioma 175 | 3,232
Cancer 163 | 2,499
adult high grade glioma 153 | 3,801
Kidney cancer 138 | 2,613
oligodendroglioma 138 | 2,850
primitive neuroectodermal tumor 138 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 136 | 3,291
non-small cell lung cancer 129 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 123 | 2,989
astrocytic glioma 116 | 2,597
Multiple myeloma 115 | 1,332
invasive ductal carcinoma 115 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 113 | 2,955
Pick disease 104 | 1,894
Astrocytoma, Pilocytic 101 | 3,081
pancreatic cancer 100 | 2,398
subependymal giant cell astrocytoma 90 | 2,287
lung adenocarcinoma 89 | 2,716
acute quadriplegic myopathy 86 | 1,158
tuberculosis 85 | 2,010
juvenile dermatomyositis 84 | 1,187
dermatomyositis 83 | 966
astrocytoma 77 | 1,146
Waldenstrons macroglobulinemia 76 | 765
lung carcinoma 75 | 2,843
Intellectual disability 74 | 1,016
Rheumatoid arthritis 73 | 1,191
diabetes mellitus 73 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 73 | 1,962
pituitary cancer 73 | 1,972
ductal carcinoma in situ 71 | 1,745
group 4 medulloblastoma 67 | 1,855
breast carcinoma 66 | 1,638
acute myeloid leukemia 62 | 783
ulcerative colitis 62 | 1,819
interstitial cystitis 60 | 2,312
adrenocortical carcinoma 58 | 1,428
colon cancer 54 | 1,478
primary pancreatic ductal adenocarcinoma 53 | 1,109
progressive supranuclear palsy 53 | 676
spina bifida 53 | 1,074
Dull intelligence 48 | 645
Low intelligence 48 | 645
Mental Retardation 48 | 645
Mental deficiency 48 | 645
Poor school performance 48 | 645
Autosomal recessive predisposition 46 | 1,442
cutaneous lupus erythematosus 46 | 1,057
pediatric high grade glioma 46 | 1,064
primary Sjogren syndrome 44 | 735
Short stature 42 | 531
non primary Sjogren syndrome sicca 41 | 891
Schizophrenia 39 | 1,160
tuberculosis and treatment for 6 months 38 | 409
Cognitive delay 37 | 608
Global developmental delay 37 | 608
Mental and motor retardation 37 | 608
Amyotrophic lateral sclerosis 35 | 451
cystic fibrosis 35 | 1,696
Small head 33 | 374
nasopharyngeal carcinoma 33 | 1,058
autosomal dominant Emery-Dreifuss muscular dystrophy 32 | 510
hepatocellular carcinoma 32 | 547
Atopic dermatitis 30 | 952
Epilepsy 30 | 792
gastric carcinoma 30 | 807
Liver cancer 28 | 604
Muscle hypotonia 28 | 571
active Crohn's disease 28 | 922
aldosterone-producing adenoma 28 | 665
Prostatic Neoplasms 27 | 495
Bipolar Disorder 26 | 666
Breast Neoplasms 26 | 445
Endometriosis 26 | 540
Mammary Neoplasms 26 | 425
Osteoporosis 26 | 363
sonic hedgehog group medulloblastoma 26 | 467
Obesity 25 | 678
Seizures 25 | 596
Alzheimer's disease 24 | 658
Broad flat nasal bridge 24 | 236
Hypoplastic mandible condyle 24 | 275
Mandibular hypoplasia 24 | 275
Melanoma 24 | 711
Micrognathism 24 | 275
Nasal bridge wide 24 | 236
Neurodegenerative disease 23 | 414
gastric cancer 23 | 459
Down syndrome 22 | 499

Tissue

Endocrine System 717 | 18,159
Female tissues 714 | 17,400
Digestive Tract 711 | 17,369
Male tissues 710 | 17,142
Nervous System 708 | 16,725
Skin and soft tissues 707 | 17,230
Blood and immune system 705 | 16,909
Liver and Pancreas 705 | 16,750
Urinary Tract 702 | 16,678
Respiratory system 700 | 16,393
Cardiovascular System 686 | 15,192

Target Family

Non-IDG 404 | 12,091
Enzyme 141 | 4,145
Transcription Factor 87 | 1,400
Kinase 43 | 634
Epigenetic 27 | 242
Nuclear Receptor 10 | 48
TF/Epigenetic 7 | 38
GPCR 2 | 408
Ion Channel 2 | 344
Transporter 2 | 473

Compartment GO Term

Nuclear body 725 | 725
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Eukaryotic translation initiation factor 4E transporter EIF4ENIF1 Tbio Non-IDG -1.60874 36.7 242
ETS-related transcription factor Elf-2 ELF2 Tbio Transcription Factor -2.04794 106.4 92
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69
Tripeptidyl-peptidase 2 TPP2 Tbio Enzyme -1.97332 108.2 72
RNA-binding protein 39 RBM39 Tbio Non-IDG -0.95639 9.80 199