Development Level

Tbio 273 | 10,625
Tchem 45 | 1,890
Tdark 29 | 7,003
Tclin 2 | 602

Collection

Eligible Kinase Proteins 5 | 134

IMPC Term

preweaning lethality, complete... 28 | 633
preweaning lethality, incomple... 8 | 260
embryonic lethality prior to t... 7 | 187
embryonic lethality prior to o... 6 | 148
decreased body weight 5 | 174
decreased lean body mass 5 | 195
abnormal retina morphology 4 | 100
decreased grip strength 4 | 123
decreased leukocyte cell numbe... 4 | 54
decreased rib number 4 | 59
decreased total body fat amoun... 4 | 186
hyperactivity 4 | 108
prenatal lethality prior to he... 4 | 64
abnormal bone mineralization 3 | 55
abnormal heart morphology 3 | 51
abnormal maxilla morphology 3 | 16
abnormal retinal pigmentation 3 | 61
decreased body length 3 | 108
decreased circulating LDL chol... 3 | 37
decreased circulating glucose ... 3 | 121
decreased circulating iron lev... 3 | 25
decreased hemoglobin content 3 | 53
increased heart weight 3 | 37
increased or absent threshold ... 3 | 128
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal eye morphology 2 | 38
abnormal locomotor activation 2 | 26
abnormal snout morphology 2 | 18
abnormal startle reflex 2 | 14
abnormal tooth morphology 2 | 24
decreased Ly6C low monocyte nu... 2 | 23
decreased bone mineral content 2 | 157
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating calcium ... 2 | 33
decreased circulating chloride... 2 | 32
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased erythrocyte cell num... 2 | 43
decreased hematocrit 2 | 25
decreased monocyte cell number 2 | 28
decreased neutrophil cell numb... 2 | 37
decreased prepulse inhibition 2 | 52
decreased respiratory quotient 2 | 12
enlarged heart 2 | 111
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating amylase ... 2 | 13
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased lean body mass 2 | 107
limb grasping 2 | 35
thrombocytosis 2 | 23
tremors 2 | 34
abnormal coat appearance 1 | 25
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
abnormal neural tube morpholog... 1 | 8
abnormal respiratory quotient 1 | 9
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal vertebrae morphology 1 | 14
decreased KLRG1+ CD4 alpha bet... 1 | 2
decreased Ly6C high monocyte n... 1 | 18
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased thoracic vertebrae n... 1 | 7
decreased total retina thickne... 1 | 20
hypoactivity 1 | 89
impaired righting response 1 | 19
increased NK T cell number 1 | 11
increased body length 1 | 20
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating glycerol... 1 | 11
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
long tibia 1 | 13
oligodactyly 1 | 14
premature death 1 | 5
small thymus 1 | 11

Disease

ovarian cancer 221 | 8,484
osteosarcoma 175 | 7,933
psoriasis 138 | 6,685
medulloblastoma, large-cell 136 | 6,234
lung cancer 114 | 4,466
glioblastoma 108 | 5,572
atypical teratoid / rhabdoid tumor 91 | 4,369
Cancer 87 | 2,346
malignant mesothelioma 79 | 3,162
Multiple myeloma 68 | 1,327
group 3 medulloblastoma 68 | 2,254
oligodendroglioma 66 | 2,849
Breast cancer 65 | 3,094
Carcinoma 63 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 62 | 3,289
primitive neuroectodermal tumor 62 | 3,031
ependymoma 60 | 2,514
Pick disease 56 | 1,893
Waldenstrons macroglobulinemia 54 | 765
intraductal papillary-mucinous adenoma (IPMA) 54 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,988
acute quadriplegic myopathy 51 | 1,157
dermatomyositis 49 | 933
adult high grade glioma 47 | 2,148
astrocytic glioma 47 | 2,241
juvenile dermatomyositis 47 | 1,189
non-small cell lung cancer 44 | 2,798
pediatric high grade glioma 44 | 2,712
subependymal giant cell astrocytoma 44 | 2,287
astrocytoma 42 | 1,493
diabetes mellitus 42 | 1,663
pilocytic astrocytoma 41 | 3,086
invasive ductal carcinoma 40 | 2,950
group 4 medulloblastoma 39 | 1,875
Rheumatoid Arthritis 38 | 1,160
pancreatic cancer 38 | 2,300
progressive supranuclear palsy 34 | 674
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,795
acute myeloid leukemia 32 | 780
lung adenocarcinoma 32 | 2,713
pituitary cancer 31 | 1,972
ulcerative colitis 31 | 2,087
sonic hedgehog group medulloblastoma 30 | 1,482
Intellectual disability 28 | 573
tuberculosis 27 | 1,557
tuberculosis and treatment for 6 months 27 | 686
lung carcinoma 25 | 2,844
breast carcinoma 24 | 1,614
colon cancer 24 | 1,475
primary Sjogren syndrome 24 | 789
ductal carcinoma in situ 22 | 1,745
medulloblastoma 22 | 1,524
primary pancreatic ductal adenocarcinoma 22 | 1,271
adrenocortical carcinoma 21 | 1,427
Amyotrophic Lateral Sclerosis 20 | 431
non primary Sjogren syndrome sicca 20 | 840
cutaneous lupus erythematosus 19 | 1,056
interstitial cystitis 19 | 2,299
posterior fossa group B ependymoma 19 | 1,530
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 499
posterior fossa group A ependymoma 18 | 1,511
spina bifida 18 | 1,064
Mammary Neoplasms 16 | 410
atypical teratoid/rhabdoid tumor 16 | 1,095
Alzheimer's disease 14 | 644
Prostatic Neoplasms 14 | 471
aldosterone-producing adenoma 14 | 664
glioblastoma multiforme 14 | 347
hepatocellular carcinoma 14 | 532
Down syndrome 13 | 548
Muscular atrophy 13 | 67
cystic fibrosis 13 | 1,665
gastric carcinoma 13 | 832
Neurodegenerative disease 12 | 383
nasopharyngeal carcinoma 12 | 1,056
pancreatic carcinoma 12 | 567
IGA Glomerulonephritis 11 | 454
Parkinson's disease 11 | 364
Renal Cell Carcinoma 11 | 199
inflammatory breast cancer 11 | 404
Gaucher disease type 1 10 | 171
Microcephaly 10 | 149
Vascular disease 10 | 281
Diabetes Mellitus, Non-Insulin-Dependent 9 | 157
Duchenne muscular dystrophy 9 | 602
HIV Infections 9 | 100
Kidney cancer 9 | 118
Leukemia 9 | 88
Liver carcinoma 9 | 217
Melanoma 9 | 261
Obesity 9 | 616
Prostate cancer 9 | 172
active Crohn's disease 9 | 918
gastric cancer 9 | 430
tuberculosis and treatment for 3 months 9 | 327
Kidney disease 8 | 396
Multiple Sclerosis 8 | 498
Polycystic Ovary Syndrome 8 | 332
Schizophrenia 8 | 501
mucosa-associated lymphoid tissue lymphoma 8 | 480

Tissue

Female tissues 345 | 18,647
Blood and immune system 344 | 17,995
Male tissues 344 | 17,969
Nervous System 344 | 18,561
Cardiovascular System 343 | 17,958
Digestive Tract 343 | 18,473
Liver and Pancreas 343 | 18,136
Endocrine System 342 | 18,512
Urinary Tract 340 | 18,444
Respiratory system 339 | 17,484
Skin and soft tissues 337 | 18,115

Target Family

Non-IDG 210 | 11,971
Enzyme 59 | 4,146
Transcription Factor 39 | 1,400
Kinase 22 | 634
Epigenetic 13 | 242
TF/Epigenetic 4 | 38
Nuclear Receptor 2 | 48

Compartment GO Term

Nuclear body 349 | 349
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
Basic helix-loop-helix transcription factor scleraxis SCX Tbio Transcription Factor -2.80657 344.1 42
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.20916 14.6 78
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
Zinc finger protein GLIS2 GLIS2 Tbio Transcription Factor -1.86726 74.7 85
Serine/arginine repetitive matrix protein 2 SRRM2 Tbio Non-IDG -1.90106 71.6 51
PHD finger-like domain-containing protein 5A PHF5A Tbio Epigenetic -1.94489 96.2 127
Cyclic AMP-responsive element-binding protein 3 CREB3 Tbio Transcription Factor -1.61736 42.0 159
Myb/SANT-like DNA-binding domain-containing protein 1 MSANTD1 Tdark Non-IDG 0.00000 22
Transcriptional repressor p66-alpha GATAD2A Tbio Non-IDG -0.79314 7.11 142