Development Level

Tbio 304 | 11,445
Tdark 112 | 6,588
Tchem 29 | 1,598
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 38 | 979
preweaning lethality, incomple... 14 | 499
abnormal behavior 12 | 298
decreased total body fat amoun... 10 | 207
enlarged heart 9 | 210
abnormal heart morphology 8 | 162
embryonic lethality prior to t... 7 | 278
hypoactivity 7 | 132
increased bone mineral content 7 | 108
increased lean body mass 7 | 172
abnormal bone structure 6 | 187
abnormal embryo size 6 | 220
decreased vertical activity 6 | 208
embryonic lethality prior to o... 6 | 239
male infertility 6 | 123
abnormal seminal vesicle morph... 5 | 114
decreased circulating choleste... 5 | 93
abnormal spleen morphology 4 | 55
corneal opacity 4 | 32
decreased body length 4 | 101
decreased body weight 4 | 161
decreased bone mineral content 4 | 151
decreased bone mineral density 4 | 126
decreased lean body mass 4 | 135
hyperactivity 4 | 148
impaired glucose tolerance 4 | 75
increased circulating HDL chol... 4 | 80
increased grip strength 4 | 41
increased mean corpuscular hem... 4 | 96
increased mean corpuscular vol... 4 | 92
increased mean platelet volume 4 | 45
increased or absent threshold ... 4 | 101
abnormal retina morphology 3 | 71
anophthalmia 3 | 33
decreased circulating insulin ... 3 | 76
decreased lymphocyte cell numb... 3 | 83
decreased prepulse inhibition 3 | 82
decreased startle reflex 3 | 75
female infertility 3 | 60
increased body length 3 | 32
increased bone mineral density 3 | 72
increased circulating choleste... 3 | 66
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 36
increased total body fat amoun... 3 | 134
prenatal lethality prior to he... 3 | 87
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal skin morphology 2 | 50
abnormal snout morphology 2 | 23
abnormal testis morphology 2 | 43
abnormal vitreous body morphol... 2 | 10
cataract 2 | 92
decreased circulating HDL chol... 2 | 68
decreased circulating glucose ... 2 | 126
decreased circulating potassiu... 2 | 20
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased red blood cell distr... 2 | 41
edema 2 | 59
enlarged spleen 2 | 41
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating magnesiu... 2 | 10
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased red blood cell distr... 2 | 34
microphthalmia 2 | 26
persistence of hyaloid vascula... 2 | 33
small superior vagus ganglion 2 | 74
small thymus 2 | 16
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal head morphology 1 | 10
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal vocalization 1 | 21
decreased caudal vertebrae num... 1 | 53
decreased circulating calcium ... 1 | 36
decreased eosinophil cell numb... 1 | 24
decreased fluid intake 1 | 3
decreased neutrophil cell numb... 1 | 42
impaired pupillary reflex 1 | 26
increased body weight 1 | 25
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased startle reflex 1 | 112
iris synechia 1 | 3
long tibia 1 | 25
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 282 | 11,493
ovarian cancer 244 | 8,520
osteosarcoma 208 | 7,950
medulloblastoma, large-cell 153 | 6,241
psoriasis 152 | 6,694
glioblastoma 147 | 5,792
atypical teratoid / rhabdoid tumor 128 | 5,112
ependymoma 119 | 4,679
group 3 medulloblastoma 118 | 4,104
lung cancer 111 | 4,740
Breast cancer 106 | 3,578
adult high grade glioma 89 | 3,801
malignant mesothelioma 88 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 84 | 3,291
primitive neuroectodermal tumor 79 | 3,035
invasive ductal carcinoma 78 | 2,951
non-small cell lung cancer 76 | 2,890
Cancer 70 | 2,499
oligodendroglioma 68 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,989
Astrocytoma, Pilocytic 65 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 63 | 2,955
astrocytic glioma 62 | 2,597
pancreatic cancer 58 | 2,398
lung adenocarcinoma 56 | 2,716
lung carcinoma 56 | 2,843
Pick disease 54 | 1,894
Kidney cancer 53 | 2,613
subependymal giant cell astrocytoma 50 | 2,287
ductal carcinoma in situ 46 | 1,745
pituitary cancer 46 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 44 | 1,962
group 4 medulloblastoma 43 | 1,855
interstitial cystitis 42 | 2,312
Intellectual disability 41 | 1,016
breast carcinoma 41 | 1,638
juvenile dermatomyositis 40 | 1,187
ulcerative colitis 40 | 1,819
Multiple myeloma 39 | 1,332
diabetes mellitus 38 | 1,728
Rheumatoid arthritis 36 | 1,191
acute quadriplegic myopathy 36 | 1,158
acute myeloid leukemia 35 | 783
astrocytoma 34 | 1,146
cutaneous lupus erythematosus 34 | 1,057
dermatomyositis 34 | 966
adrenocortical carcinoma 33 | 1,428
colon cancer 33 | 1,478
tuberculosis 33 | 2,010
cystic fibrosis 32 | 1,696
primary pancreatic ductal adenocarcinoma 31 | 1,109
Waldenstrons macroglobulinemia 28 | 765
medulloblastoma 28 | 720
Dull intelligence 27 | 645
Low intelligence 27 | 645
Mental Retardation 27 | 645
Mental deficiency 27 | 645
Poor school performance 27 | 645
spina bifida 27 | 1,074
Atopic dermatitis 25 | 952
active Crohn's disease 24 | 922
Cognitive delay 23 | 608
Global developmental delay 23 | 608
Mental and motor retardation 23 | 608
Short stature 23 | 531
pediatric high grade glioma 23 | 1,064
Autosomal recessive predisposition 21 | 1,442
Schizophrenia 21 | 1,160
aldosterone-producing adenoma 21 | 665
tuberculosis and treatment for 6 months 21 | 409
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 510
progressive supranuclear palsy 20 | 676
Small head 19 | 374
Muscle hypotonia 18 | 571
gastric carcinoma 18 | 807
nasopharyngeal carcinoma 18 | 1,058
Bipolar Disorder 16 | 666
hepatocellular carcinoma 16 | 547
non primary Sjogren syndrome sicca 16 | 891
Duchenne muscular dystrophy 15 | 601
Epilepsy 15 | 792
Seizures 15 | 596
gastric cancer 15 | 459
Acquired scoliosis 14 | 281
Blepharoptosis 14 | 231
Cryptorchidism 14 | 296
Curvature of spine 14 | 282
Liver Cirrhosis, Experimental 14 | 769
pancreatic carcinoma 14 | 562
primary Sjogren syndrome 14 | 735
Multiple Sclerosis 13 | 540
Prostatic Neoplasms 13 | 495
active ulcerative colitis 13 | 764
posterior fossa group B ependymoma 13 | 416
Alzheimer's disease 12 | 658
Cleft Palate 12 | 271
Endometriosis 12 | 540
chronic rhinosinusitis 12 | 512
mucosa-associated lymphoid tissue lymphoma 12 | 484
sonic hedgehog group medulloblastoma 12 | 467

Tissue

Endocrine System 447 | 18,159
Skin and soft tissues 444 | 17,230
Female tissues 442 | 17,400
Male tissues 441 | 17,142
Digestive Tract 440 | 17,369
Nervous System 437 | 16,725
Liver and Pancreas 435 | 16,750
Respiratory system 435 | 16,393
Urinary Tract 435 | 16,678
Blood and immune system 433 | 16,909
Cardiovascular System 425 | 15,192

Target Family

Non-IDG 256 | 12,091
Enzyme 81 | 4,145
Transcription Factor 71 | 1,400
Epigenetic 14 | 242
Kinase 13 | 634
TF/Epigenetic 5 | 38
Nuclear Receptor 4 | 48
Ion Channel 3 | 344
Transporter 2 | 473
GPCR 1 | 408

Compartment GO Term

Nuclear bodies 450 | 450
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein Helios IKZF2 Tbio Transcription Factor -1.26324 15.8 221
CDK5 and ABL1 enzyme substrate 2 CABLES2 Tdark Non-IDG 0.08 1.29 75
Atrial natriuretic peptide-converting enzyme CORIN Tbio Non-IDG -2.14443 144.4 221
Protein HGH1 homolog HGH1 Tdark Non-IDG 0.00000 119
Glycerol-3-phosphate phosphatase PGP Tbio Enzyme -1.48294 30.0 90
F-box only protein 48 FBXO48 Tdark Non-IDG 0.30 0.67 21
Testis-specific serine/threonine-protein kinase 3 TSSK3 Tbio Kinase -0.52985 3.86 47
Zinc finger protein 792 ZNF792 Tdark Transcription Factor 0.00000 24
Zinc finger BED domain-containing protein 2 ZBED2 Tdark Transcription Factor 0.61 0.24 51
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419