Development Level

Tbio 106 | 10,625
Tdark 17 | 7,003
Tchem 4 | 1,890
Tclin 1 | 602

IMPC Phenotype

preweaning lethality, complete... 15 | 633
embryonic lethality prior to o... 8 | 148
embryonic lethality prior to t... 6 | 187
abnormal embryo size 2 | 112
abnormal retina morphology 2 | 100
decreased leukocyte cell numbe... 2 | 54
decreased rib number 2 | 59
decreased total body fat amoun... 2 | 186
increased bone mineral content 2 | 92
increased circulating magnesiu... 2 | 10
prenatal lethality prior to he... 2 | 64
abnormal behavior 1 | 226
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal hair growth 1 | 8
abnormal iris morphology 1 | 12
decreased B cell number 1 | 30
decreased CD103-positive CD11b... 1 | 2
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
enlarged lymph nodes 1 | 27
enlarged urinary bladder 1 | 4
hypoactivity 1 | 89
increased bone mineral density 1 | 52
increased circulating free fat... 1 | 17
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
vertebral transformation 1 | 12

Disease

ovarian cancer 64 | 8,491
osteosarcoma 55 | 7,933
lung cancer 37 | 4,473
psoriasis 27 | 6,685
medulloblastoma, large-cell 26 | 6,234
glioblastoma 23 | 5,572
malignant mesothelioma 23 | 3,163
group 3 medulloblastoma 20 | 2,254
Multiple myeloma 18 | 1,327
Carcinoma 16 | 2,147
atypical teratoid / rhabdoid tumor 16 | 4,369
oligodendroglioma 15 | 2,849
Cancer 14 | 2,346
astrocytic glioma 14 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
Breast cancer 13 | 3,098
Cockayne syndrome 13 | 54
ependymoma 13 | 2,514
primitive neuroectodermal tumor 13 | 3,031
pediatric high grade glioma 11 | 2,712
Photosensitive trichothiodystrophy 10 | 24
Pick disease 10 | 1,893
lung adenocarcinoma 10 | 2,714
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
Waldenstrons macroglobulinemia 9 | 764
diabetes mellitus 9 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
tuberculosis 9 | 1,563
acute myeloid leukemia 8 | 785
invasive ductal carcinoma 8 | 2,950
non-small cell lung cancer 8 | 2,798
Xeroderma pigmentosum 7 | 41
astrocytoma 7 | 1,493
group 4 medulloblastoma 7 | 1,875
tuberculosis and treatment for 6 months 7 | 686
adult high grade glioma 6 | 2,148
aldosterone-producing adenoma 6 | 664
hepatocellular carcinoma 6 | 550
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
medulloblastoma 6 | 1,524
non primary Sjogren syndrome sicca 6 | 840
pancreatic cancer 6 | 2,300
pituitary cancer 6 | 1,972
sonic hedgehog group medulloblastoma 6 | 1,482
subependymal giant cell astrocytoma 6 | 2,287
Epidermodysplasia verruciformis 5 | 21
Intellectual disability 5 | 573
Peripheral Neuropathy 5 | 303
Spinocerebellar ataxia type 7 5 | 13
acute quadriplegic myopathy 5 | 1,157
adrenocortical carcinoma 5 | 1,427
colon cancer 5 | 1,475
cystic fibrosis 5 | 1,670
nasopharyngeal carcinoma 5 | 1,056
pilocytic astrocytoma 5 | 3,086
posterior fossa group A ependymoma 5 | 1,511
Treacher Collins syndrome 4 | 29
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
lung carcinoma 4 | 2,844
pancreatic carcinoma 4 | 567
spina bifida 4 | 1,064
Baller-Gerold syndrome 3 | 14
Endometriosis 3 | 535
Gaucher disease type 1 3 | 171
Hypomyelination-hypogonadotropic-hypogonadism-hypodontia syndrome 3 | 3
IGA Glomerulonephritis 3 | 454
Leukodystrophy 3 | 30
Rheumatoid Arthritis 3 | 1,170
Rothmund-Thomson syndrome 3 | 22
Stomach Neoplasms 3 | 282
Tooth agenesis 3 | 38
Trichothiodystrophy 1, photosensitive 3 | 4
Trichothiodystrophy Syndromes 3 | 5
Werner syndrome 3 | 29
gastric cancer 3 | 436
interstitial cystitis 3 | 2,299
juvenile dermatomyositis 3 | 1,189
Acquired metabolic disease 2 | 267
Adrenoleukodystrophy, Neonatal 2 | 13
Atopic dermatitis 2 | 944
Attention deficit hyperactivity disorder 2 | 156
Cardiovascular system disease 2 | 194
Cataract 2 | 104
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Huntington's disease 2 | 72
Infantile Refsum Disease (disorder) 2 | 13
Infertility 2 | 163
Male infertility 2 | 170
Peroxisome biogenesis disorders 2 | 11
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 503
Substance-Related Disorders 2 | 114
Zellweger Syndrome 2 | 38
active Crohn's disease 2 | 918
hereditary spastic paraplegia 2 | 313
primary pancreatic ductal adenocarcinoma 2 | 1,271
progressive supranuclear palsy 2 | 674

Tissue

Blood and immune system 127 | 17,994
Cardiovascular System 127 | 17,957
Female tissues 127 | 18,646
Liver and Pancreas 127 | 18,135
Male tissues 127 | 17,968
Nervous System 127 | 18,560
Digestive Tract 126 | 18,472
Endocrine System 126 | 18,511
Urinary Tract 126 | 18,443
Respiratory system 125 | 17,483
Skin and soft tissues 125 | 18,114

Target Family

Non-IDG 62 | 11,969
Enzyme 58 | 4,146
Epigenetic 5 | 242
Kinase 3 | 634

Compartment GO Term

Nuclear DNA-directed RNA polym... 128 | 128
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.47495 286.5 135
DNA-directed RNA polymerase III subunit RPC7-like POLR3GL Tbio Enzyme -1.46920 28.5 54
Transcription initiation factor IIA subunit 2 GTF2A2 Tbio Non-IDG -1.17322 15.5 31
Transcription initiation factor IIA subunit 1 GTF2A1 Tchem Non-IDG -0.11090 0.73 228
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.14104 13.5 159
DNA-directed RNA polymerase II subunit RPB11-a POLR2J Tbio Enzyme -1.42612 28.8 182
TFIIA-alpha and beta-like factor GTF2A1L Tbio Non-IDG -0.66901 3.86 184
General transcription factor IIH subunit 3 GTF2H3 Tbio Non-IDG -0.87291 6.02 65
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -1.31733 6.84 120
Integrator complex subunit 11 CPSF3L Tbio Non-IDG -0.79472 5.46 101