Development Level

Tbio 20 | 11,651

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased body weight 3 | 161
abnormal behavior 2 | 298
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal vertebral arch morpho... 1 | 9
cataract 1 | 92
decreased IgG2b level 1 | 4
decreased cardiac stroke volum... 1 | 6
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased vertical activity 1 | 208
increased circulating alkaline... 1 | 122
increased circulating creatine... 1 | 5
increased circulating magnesiu... 1 | 10
increased lactate dehydrogenas... 1 | 3
increased respiratory quotient 1 | 2
thrombocytopenia 1 | 56

Disease

Carcinoma 15 | 11,493
ovarian cancer 15 | 8,520
osteosarcoma 13 | 7,950
Breast cancer 9 | 3,578
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
group 3 medulloblastoma 7 | 4,104
malignant mesothelioma 7 | 3,232
medulloblastoma, large-cell 7 | 6,241
atypical teratoid / rhabdoid tumor 6 | 5,112
primitive neuroectodermal tumor 6 | 3,035
Cancer 5 | 2,499
Rheumatoid arthritis 5 | 1,191
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
Multiple myeloma 4 | 1,332
astrocytoma 4 | 1,146
hepatocellular carcinoma 4 | 547
Alzheimer's disease 3 | 658
Intellectual disability 3 | 1,016
adult high grade glioma 3 | 3,801
colon cancer 3 | 1,478
dermatomyositis 3 | 966
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non-small cell lung cancer 3 | 2,890
Adenoid Cystic Carcinoma 2 | 99
Broad flat nasal bridge 2 | 236
Carcinoma, Adenoid Cystic 2 | 99
Cognitive delay 2 | 608
Dull intelligence 2 | 645
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Global developmental delay 2 | 608
Liver cancer 2 | 604
Low intelligence 2 | 645
Low posterior hairline 2 | 52
Macrostomia 2 | 72
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Nasal bridge wide 2 | 236
Pick disease 2 | 1,894
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Short neck 2 | 140
Short stature 2 | 531
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
tuberculosis 2 | 2,010
3-M syndrome 1 | 15
Agyria 1 | 15
Animal Mammary Neoplasms 1 | 136
Baraitser-Winter syndrome 1 | 12
Brachydactyly 1 | 156
Broad thumbs 1 | 28
COPD 1 | 118
Celiac disease 1 | 116
Cleft palate with cleft lip 1 | 23
Craniofacial Abnormalities 1 | 151
Death in early adulthood 1 | 24
Deglutition Disorders 1 | 132
Enophthalmos 1 | 75
Esophageal Achalasia 1 | 9
Esophageal Neoplasms 1 | 69
Generalized hirsutism 1 | 36
Hirsutism 1 | 47
Hyperplasia of nose 1 | 23
Hypertrophy of nose 1 | 23
Immunologic Deficiency Syndromes 1 | 113
Intracranial aneurysm 1 | 24
Joint stiffness 1 | 84
Kyphoscoliosis deformity of spine 1 | 60
Large nose 1 | 23
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mental deterioration 1 | 32
Oral cleft 1 | 18
Pointed chin 1 | 33
Recurrent otitis media 1 | 42
Sunken eyes 1 | 63
Tethered spinal cord syndrome 1 | 11
Thin upper lip vermilion 1 | 67
Velocardiofacial syndrome 1 | 46
Xeroderma pigmentosum group B 1 | 20
inflammatory breast cancer 1 | 286
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Non-IDG 13 | 12,091
Epigenetic 5 | 242
Enzyme 2 | 4,145

Compartment GO Term

NuA4 histone acetyltransferase... 20 | 20
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69
MRG/MORF4L-binding protein MRGBP Tbio Non-IDG -0.74186 5.72 147
Transformation/transcription domain-associated protein TRRAP Tbio Non-IDG -1.62460 39.0 162
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
Enhancer of polycomb homolog 2 EPC2 Tbio Non-IDG -1.32982 17.5 51
Histone acetyltransferase KAT5 KAT5 Tbio Epigenetic -2.29449 194.7 504
Actin-like protein 6A ACTL6A Tbio Non-IDG -1.45479 28.3 286
Mortality factor 4-like protein 2 MORF4L2 Tbio Non-IDG -0.87952 8.10 128
DNA methyltransferase 1-associated protein 1 DMAP1 Tbio Enzyme -1.20904 16.0 220
Enhancer of polycomb homolog 1 EPC1 Tbio Non-IDG -1.32335 19.2 62