Development Level

Tbio 89 | 10,625
Tdark 16 | 7,003
Tchem 9 | 1,890
Tclin 6 | 602

Collection

Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 5 | 633
decreased body weight 4 | 174
abnormal behavior 3 | 226
decreased circulating amylase ... 3 | 24
decreased circulating triglyce... 3 | 83
hyperactivity 3 | 108
hypoactivity 3 | 89
abnormal bone mineralization 2 | 55
decreased prepulse inhibition 2 | 52
limb grasping 2 | 35
prenatal lethality prior to he... 2 | 64
vertebral fusion 2 | 23
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal cervical vertebrae mo... 1 | 4
abnormal ear morphology 1 | 5
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal glucose homeostasis 1 | 5
abnormal heart left ventricle ... 1 | 20
abnormal locomotor activation 1 | 26
abnormal nail morphology 1 | 7
abnormal respiratory quotient 1 | 9
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 21
absent startle reflex 1 | 15
convulsive seizures 1 | 11
decreased CD4-positive, alpha ... 1 | 19
decreased body length 1 | 108
decreased body temperature 1 | 2
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating total pr... 1 | 41
decreased coping response 1 | 5
decreased erythrocyte cell num... 1 | 43
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased startle reflex 1 | 48
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
enlarged uterus 1 | 3
hydrometra 1 | 13
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased blood uric acid leve... 1 | 5
increased body weight 1 | 42
increased cellular hemoglobin ... 1 | 2
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart rate 1 | 17
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
macrophthalmia 1 | 2
male infertility 1 | 62
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
preweaning lethality, incomple... 1 | 260
shortened RR interval 1 | 19
small superior vagus ganglion 1 | 20
small testis 1 | 37
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

osteosarcoma 47 | 7,933
Retinitis pigmentosa 44 | 153
ovarian cancer 39 | 8,484
medulloblastoma, large-cell 34 | 6,234
psoriasis 34 | 6,685
glioblastoma 32 | 5,572
Fundus dystrophy 29 | 77
Nephronophthisis 29 | 74
posterior fossa group B ependymoma 28 | 1,530
lung cancer 24 | 4,466
Leber congenital amaurosis 23 | 72
Blindness 21 | 84
Cone dystrophy 21 | 57
lung adenocarcinoma 21 | 2,713
Breast cancer 20 | 3,094
atypical teratoid / rhabdoid tumor 20 | 4,369
Carcinoma 19 | 2,147
Ciliopathy 19 | 57
Joubert syndrome 19 | 61
Meckel syndrome 19 | 48
astrocytic glioma 19 | 2,241
chronic rhinosinusitis 19 | 512
Polydactyly 18 | 93
malignant mesothelioma 18 | 3,162
lung carcinoma 17 | 2,844
pediatric high grade glioma 17 | 2,712
ependymoma 16 | 2,514
group 3 medulloblastoma 16 | 2,254
primitive neuroectodermal tumor 16 | 3,031
Cancer 15 | 2,346
Senior-Loken syndrome 15 | 21
cone-rod dystrophy 15 | 56
pituitary cancer 14 | 1,972
pilocytic astrocytoma 13 | 3,086
subependymal giant cell astrocytoma 13 | 2,287
Cystic kidney disease 12 | 25
Meckel-Gruber syndrome 12 | 15
Night Blindness 12 | 39
Retinal Degeneration 12 | 49
invasive ductal carcinoma 12 | 2,950
non-small cell lung cancer 12 | 2,798
oligodendroglioma 12 | 2,849
tuberculosis 12 | 1,557
Intellectual disability 11 | 573
group 4 medulloblastoma 11 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
medulloblastoma 11 | 1,524
ulcerative colitis 11 | 2,087
Bardet-Biedl Syndrome 10 | 40
Nonsyndromic deafness 10 | 121
pancreatic cancer 10 | 2,300
Renal dysplasia and retinal aplasia (disorder) 9 | 10
Rheumatoid Arthritis 9 | 1,160
adult high grade glioma 9 | 2,148
atypical teratoid/rhabdoid tumor 9 | 1,095
interstitial cystitis 9 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
Obesity 8 | 616
Pick disease 8 | 1,893
Thrombocytopenia 8 | 105
astrocytoma 8 | 1,493
breast carcinoma 8 | 1,614
colon cancer 8 | 1,475
progressive supranuclear palsy 8 | 674
Asphyxiating thoracic dystrophy 7 | 32
Familial aplasia of the vermis 7 | 8
Orofaciodigital syndrome 7 | 19
active Crohn's disease 7 | 918
nasopharyngeal carcinoma 7 | 1,056
sonic hedgehog group medulloblastoma 7 | 1,482
Age related macular degeneration 6 | 84
Anemia 6 | 252
Schizophrenia 6 | 501
Situs Inversus 6 | 48
adrenocortical carcinoma 6 | 1,427
cystic fibrosis and chronic rhinosinusitis 6 | 213
facioscapulohumeral dystrophy 6 | 286
Asthma 5 | 349
Coloboma 5 | 51
Hydrolethalus syndrome 5 | 128
Neutropenia 5 | 78
Polycystic kidney disease 5 | 54
Usher syndrome 5 | 34
Vitelliform macular dystrophy 5 | 14
diabetes mellitus 5 | 1,663
non primary Sjogren syndrome sicca 5 | 840
pancreatic carcinoma 5 | 567
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
Atopic dermatitis 4 | 944
Autoimmune thrombocytopenic purpura 4 | 14
Congenital stationary night blindness 4 | 27
Coronary artery disease 4 | 240
Kidney Diseases 4 | 86
Kidney disease 4 | 396
Liver Cirrhosis 4 | 101
Multiple myeloma 4 | 1,327
Purpura 4 | 17
Sensorineural hearing loss 4 | 107
ductal carcinoma in situ 4 | 1,745

Tissue

Nervous System 118 | 18,561
Digestive Tract 116 | 18,473
Female tissues 115 | 18,647
Urinary Tract 115 | 18,444
Blood and immune system 114 | 17,995
Endocrine System 114 | 18,512
Liver and Pancreas 113 | 18,136
Cardiovascular System 112 | 17,958
Skin and soft tissues 112 | 18,115
Male tissues 111 | 17,969
Respiratory system 109 | 17,484

Target Family

Non-IDG 82 | 11,971
Enzyme 19 | 4,146
Kinase 9 | 634
GPCR 5 | 406
Ion Channel 2 | 341
Transporter 2 | 473
Transcription Factor 1 | 1,400

Compartment GO Term

Nonmotile primary cilium 120 | 120
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Stereocilin STRC Tbio Non-IDG 35.9 7
Short-wave-sensitive opsin 1 OPN1SW Tbio GPCR -1.90084 81.3 15
Protein C21orf2 C21orf2 Tbio Non-IDG -1.66840 37.4 95
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
Retinitis pigmentosa 1-like 1 protein RP1L1 Tbio Non-IDG -1.19453 19.3 0
Recoverin RCVRN Tbio Non-IDG -2.41555 275.7 360
Nephrocystin-4 NPHP4 Tbio Non-IDG -1.39275 26.0 48
Nephrocystin-1 NPHP1 Tbio Non-IDG -1.70748 50.8 88
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 Tbio Non-IDG -1.15715 18.1 144