Development Level

Tbio 34 | 11,651
Tchem 9 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal retinal inner nuclear... 1 | 8
abnormal spinal cord morpholog... 1 | 9
abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased startle reflex 1 | 112
tremors 1 | 39

Disease

Cancer 33 | 2,499
Carcinoma 33 | 11,493
osteosarcoma 32 | 7,950
ovarian cancer 28 | 8,520
lung cancer 23 | 4,740
Breast cancer 20 | 3,578
group 3 medulloblastoma 20 | 4,104
medulloblastoma, large-cell 20 | 6,241
malignant mesothelioma 19 | 3,232
psoriasis 18 | 6,694
Nijmegen breakage syndrome 16 | 24
atypical teratoid / rhabdoid tumor 15 | 5,112
glioblastoma 14 | 5,792
primitive neuroectodermal tumor 14 | 3,035
Ataxia telangiectasia 13 | 34
Breast Neoplasms 13 | 445
Kidney cancer 13 | 2,613
Mammary Neoplasms 13 | 425
Autosomal recessive predisposition 12 | 1,442
Xeroderma pigmentosum 12 | 43
ependymoma 12 | 4,679
Intellectual disability 11 | 1,016
Short stature 11 | 531
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
non-small cell lung cancer 11 | 2,890
Fanconi anemia 10 | 56
Small head 10 | 374
colon cancer 10 | 1,478
Chromosome Breakage 9 | 36
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Prostatic Neoplasms 9 | 495
Severe combined immunodeficiency 9 | 51
Werner syndrome 9 | 29
adult high grade glioma 9 | 3,801
Hereditary Breast and Ovarian Cancer Syndrome 8 | 14
Schizophrenia 8 | 1,160
Thrombocytopenia 8 | 197
astrocytic glioma 8 | 2,597
lung adenocarcinoma 8 | 2,716
oligodendroglioma 8 | 2,850
Anemia 7 | 365
Bloom syndrome 7 | 29
Cognitive delay 7 | 608
DNA ligase IV deficiency 7 | 7
Decreased platelet count 7 | 111
Global developmental delay 7 | 608
Increased chromosomal breakage 7 | 27
Mental and motor retardation 7 | 608
Microcephaly 7 | 166
breast carcinoma 7 | 1,638
Pancreatic Neoplasm 6 | 85
Seckel syndrome 6 | 34
adrenocortical carcinoma 6 | 1,428
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
nasopharyngeal carcinoma 6 | 1,058
Acquired scoliosis 5 | 281
Adenoid Cystic Carcinoma 5 | 99
Alopecia 5 | 115
Carcinoma, Adenoid Cystic 5 | 99
Cryptorchidism 5 | 296
Curvature of spine 5 | 282
Epilepsy 5 | 792
Glioma 5 | 74
Hypoplastic mandible condyle 5 | 275
Leukopenia 5 | 72
Li-Fraumeni syndrome 5 | 13
Liver cancer 5 | 604
Malignant neoplasm of breast 5 | 15
Mandibular hypoplasia 5 | 275
Melanoma 5 | 711
Micrognathism 5 | 275
Neurodegenerative disease 5 | 414
Pancreatic Neoplasms 5 | 85
Pick disease 5 | 1,894
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
Splenomegaly 5 | 190
Stomach Neoplasms 5 | 300
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
pancreatic cancer 5 | 2,398
Cockayne syndrome 4 | 60
DOID:2627 4 | 94
Delayed bone age 4 | 136
Endometrial cancer 4 | 311
Lung Neoplasms 4 | 232
Penile hypospadias 4 | 106
Pneumonia 4 | 174
Prostate cancer 4 | 175
Short palpebral fissure 4 | 38
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819

Tissue

Blood and immune system 45 | 16,909
Endocrine System 45 | 18,159
Liver and Pancreas 45 | 16,750
Male tissues 45 | 17,142
Urinary Tract 45 | 16,678
Cardiovascular System 44 | 15,192
Digestive Tract 44 | 17,369
Female tissues 44 | 17,400
Nervous System 44 | 16,725
Respiratory system 44 | 16,393
Skin and soft tissues 44 | 17,230

Target Family

Non-IDG 21 | 12,091
Enzyme 15 | 4,145
Kinase 5 | 634
Epigenetic 3 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Nonhomologous end joining comp... 45 | 45
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial inner membrane protease ATP23 homolog ATP23 Tdark Enzyme -0.86878 7.67 43
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.79273 59.8 231
Protein artemis DCLRE1C Tbio Non-IDG -2.27419 184.9 252
DNA repair protein RAD51 homolog 3 RAD51C Tbio Non-IDG -1.92798 88.3 269
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
DNA repair protein XRCC2 XRCC2 Tbio Non-IDG -2.76304 492.9 270
DNA-dependent protein kinase catalytic subunit PRKDC Tchem Kinase -2.85973 723.4 1160
V(D)J recombination-activating protein 2 RAG2 Tbio Epigenetic -2.94111 784.2 194
DNA repair protein XRCC4 XRCC4 Tbio Non-IDG -2.38352 232.9 322