Development Level

Tclin 27 | 613
Tbio 20 | 11,445
Tchem 12 | 1,598
Tdark 9 | 6,588

Collection

Ion Channel: IDG Consortium (T... 8 | 99
RFA-RM-18-021 8 | 328

IMPC Phenotype

decreased total body fat amoun... 5 | 207
preweaning lethality, complete... 5 | 979
decreased grip strength 3 | 116
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
abnormal behavioral response t... 2 | 66
decreased body weight 2 | 161
increased circulating chloride... 2 | 41
increased mean corpuscular vol... 2 | 92
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal tail length 1 | 3
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased anxiety-related resp... 1 | 12
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Carcinoma 59 | 11,493
Schizophrenia 47 | 1,160
glioblastoma 36 | 5,792
medulloblastoma, large-cell 35 | 6,241
atypical teratoid / rhabdoid tumor 34 | 5,112
Bipolar Disorder 31 | 666
ependymoma 30 | 4,679
adult high grade glioma 29 | 3,801
psoriasis 28 | 6,694
osteosarcoma 25 | 7,950
Epilepsy 24 | 792
primitive neuroectodermal tumor 24 | 3,035
oligodendroglioma 23 | 2,850
Astrocytoma, Pilocytic 22 | 3,081
Major Depressive Disorder 22 | 301
Depressive disorder 21 | 409
Alcoholic Intoxication, Chronic 20 | 289
Kidney cancer 20 | 2,613
group 3 medulloblastoma 20 | 4,104
Mental Depression 19 | 333
astrocytic glioma 19 | 2,597
Alzheimer's disease 18 | 658
Parkinson's disease 18 | 392
ovarian cancer 18 | 8,520
Mood Disorders 17 | 184
Autistic Disorder 16 | 364
Toxic encephalopathy 16 | 141
Migraine 15 | 83
Pick disease 15 | 1,894
Unipolar Depression 15 | 250
lung carcinoma 15 | 2,843
subependymal giant cell astrocytoma 15 | 2,287
Intellectual disability 14 | 1,016
group 4 medulloblastoma 14 | 1,855
Alcohol dependence 13 | 107
Attention deficit hyperactivity disorder 13 | 278
lung cancer 13 | 4,740
Cocaine-Related Disorders 12 | 92
General anesthesia 12 | 53
Melanoma 12 | 711
Alcoholism 11 | 45
Local anesthesia 11 | 40
Migraine Prevention 11 | 23
Irritable bowel syndrome 10 | 60
Lennox-Gastaut syndrome 10 | 34
Simple partial seizure 10 | 26
Substance abuse 10 | 59
pituitary cancer 10 | 1,972
Amnestic disorder 9 | 35
Dementia 9 | 175
Pain agnosia 9 | 104
Skin cancer 9 | 469
Tonic-clonic epilepsy 9 | 47
obsessive-compulsive disorder 9 | 61
Dull intelligence 8 | 645
Epilepsy characterized by intractable complex partial seizures 8 | 28
Gastroesophageal reflux disease 8 | 110
Huntington's disease 8 | 76
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Parkinsonism 8 | 18
Poor school performance 8 | 645
Postencephalitic parkinsonism 8 | 12
astrocytoma 8 | 1,146
invasive ductal carcinoma 8 | 2,951
malignant mesothelioma 8 | 3,232
Amyotrophic lateral sclerosis 7 | 451
Arteriosclerotic Parkinsonism 7 | 8
Cancer 7 | 2,499
Cerebrovascular disease 7 | 238
Chemotherapy-induced nausea and vomiting 7 | 16
Cognitive delay 7 | 608
Extrapyramidal disease 7 | 8
Global developmental delay 7 | 608
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Mental and motor retardation 7 | 608
Prevention of Post-Operative Nausea and Vomiting 7 | 14
Seizures 7 | 596
Substance Withdrawal Syndrome 7 | 55
Amphetamine-Related Disorders 6 | 74
Autosomal recessive predisposition 6 | 1,442
Breast cancer 6 | 3,578
Constipation 6 | 181
Diabetic gastroparesis 6 | 7
Diarrhea 6 | 253
Fragile X syndrome 6 | 34
Gastrointestinal Radiography Adjunct 6 | 11
Generalized anxiety disorder 6 | 29
Intubation of gastrointestinal tract 6 | 7
Obesity 6 | 678
Psychotic Disorders 6 | 151
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890

Tissue

Endocrine System 66 | 18,159
Nervous System 65 | 16,725
Digestive Tract 60 | 17,369
Female tissues 57 | 17,400
Blood and immune system 56 | 16,909
Male tissues 55 | 17,142
Skin and soft tissues 55 | 17,230
Urinary Tract 55 | 16,678
Respiratory system 53 | 16,393
Liver and Pancreas 51 | 16,750
Cardiovascular System 41 | 15,192

Target Family

Ion Channel 27 | 344
Non-IDG 21 | 12,091
GPCR 13 | 408
Enzyme 4 | 4,145
Transporter 2 | 473
Kinase 1 | 634

Compartment GO Term

Neurotransmitter receptor comp... 68 | 68
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
5-hydroxytryptamine receptor 1F HTR1F Tchem GPCR -2.39159 244.1 131
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.18570 152.7 157
Glutamate receptor ionotropic, delta-2 GRID2 Tbio Ion Channel -2.05105 116.1 74
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.31880 213.2 64
5-hydroxytryptamine receptor 3B HTR3B Tchem Ion Channel -1.66753 42.0 91
AP-5 complex subunit beta-1 AP5B1 Tdark Non-IDG -3.06187 1110.1 7
5-hydroxytryptamine receptor 1A HTR1A Tclin GPCR -3.67718 4891.4 254